Results 231 to 240 of about 4,732,777 (361)

Survival outcomes and prognostic factors of gastric carcinoma with neuroendocrine differentiation

International Journal of Cancer, EarlyView.
What's New? Although gastric carcinoma with neuroendocrine differentiation (GCNED) is associated with more aggressive features than conventional GC, its prognosis and survival remain poorly defined. To better understand survival patterns, the authors of the present study examined clinicopathological and prognostic features of GCNED patients following ...
Jinjin Li, Chenglong Wang, Yifan Shen, Zhen Huang, Jun Zhang, Siqi Rao, Youde Cao, Jiang Min   +7 more
wiley   +1 more source

Virtual multiplex immunofluorescence identifies lymphocyte subsets predictive of response to neoadjuvant therapy. [PDF]

Ther Adv Med Oncol
Li A, Torcasso M, Woodard A, Hieromnimon H, Trujillo J, Nguyen L, Matossian M, Dolezal J, Abraham R, Clark MR, Khramtsova G, Zha Y, Giger ML, Pearson AT, Howard FM.   +14 more
europepmc   +1 more source

Organ‐sparing strategies in patients with MSI/dMMR tumors including Lynch syndrome: Current state of the art and future perspectives for clinical decision‐making

International Journal of Cancer, EarlyView.
Abstract Deficiency in DNA mismatch repair (dMMR) is a common pathway of carcinogenesis across different tumor types and confers a characteristic microsatellite instability‐high (MSI‐H) molecular phenotype. The MSI‐H/dMMR phenotype may arise from an inherited pathogenic variant in the context of Lynch syndrome and is most frequently observed in ...
Martin Duval, Antoine Dardenne, Thomas Samaille, Leo Mas, Jérémie H. Lefèvre, Xavier Dray, Mathilde Wagner, Romain Cohen, Thierry André   +8 more
wiley   +1 more source

Factors associated with neoadjuvant therapy insensitivity and its prognostic impact in HER2-positive breast cancer. [PDF]

Chin J Cancer Res
Han Y, Lan B, Peng Z, Jia Y, Ji D, Tian X, Yang Y, Sang D, Xue X, Wang J, Ma F, Luo Y, Zhang P, Xu B, Fan Y.   +14 more
europepmc   +1 more source

Distribution and prognostic value of T‐cells in primary colorectal cancer and adjacent non‐tumor mucosa in stage IV versus stage I–III patients

International Journal of Cancer, EarlyView.
What's New? While colonic mucosa lymphocytes have been quantified in the context of inflammatory diseases, T‐cells in non‐tumor mucosa adjacent to colorectal cancer remain understudied. This study found that in stage IV colorectal cancer (synchronous liver metastasis), higher Foxp3+ T‐cell density and Foxp3+/CD4+ and Foxp3+/CD8+ T‐cell ratios in non ...
Esraa Ali, Wenjing Ye, Sergii Pavlov, Lenka Červenková, Filip Ambrozkiewicz, Ondřej Vyčítal, Petr Hošek, Ondřej Daum, Václav Liška, Kari Hemminki, Andriy Trailin   +10 more
wiley   +1 more source

Total Neoadjuvant Therapy Versus Conventional Chemoradiotherapy in Rectal Cancer: Impact on Tumor Regression Grade and the Predictive Value of CEA. [PDF]

Medicina (Kaunas)
Sarafi A, Leventi A, Athitaki K, Stamou K, Papaconstantinou I, Korkolis D.   +5 more
europepmc   +1 more source

Combined computed tomography-measured tumor density and RECIST for evaluating neoadjuvant therapy in locally advanced gastrointestinal stromal tumors

, 2018
Wei‐Chih Su, Hsiang‐Lin Tsai, Yung‐Sung Yeh, Ching-Wen Huang, Cheng‐Jen Ma, Chau-Yun Chen, Tsung‐Kun Chang, Jaw‐Yuan Wang   +7 more
openalex   +1 more source

Targeting GRP78 and the Proteostasis Network to Break the Therapeutic Ceiling in Neuroendocrine Prostate Cancer

iNew Medicine, EarlyView.
ABSTRACT HSPA5 (also known as GRP78/BiP) is a master regulator of the endoplasmic reticulum (ER) stress response and a key node in the proteostasis network. In neuroendocrine prostate cancer (NEPC), an aggressive, therapy‐refractory lineage that emerges under pressure from androgen receptor (AR) directed therapies, GRP78 is upregulated and co‐opted to ...
Amos Olalekan Akinyemi, Md Rakibul Alam, Mithu Howlader, Mohammad Esfini Farahani, Lixiang Gu, Chun Li, Chripus Ngule, Kevin Fulp, Bolaji Owoyemi, Xinyi Wang, Samuel Nwadialo, Fatemeh Selani, Makumba Esoe, Obaleye Oluwafunminiyi, Zhiguo Li   +14 more
wiley   +1 more source

Molecular predictors of treatment resistance and recurrence following neoadjuvant therapy in rectal cancer. [PDF]

BMC Cancer
Huang F, McLeod MC, Irwin RK, Smithson M, Gao M, Hardiman KM, Chong Z.   +6 more
europepmc   +1 more source

MRI-based vector radiomics for predicting breast cancer HER2 status and its changes after neoadjuvant therapy

Lan Zhang, Quan‐Xiang Cui, Li Zhou, Xinyi Wang, Hongxia Zhang, Yuemin Zhu, Xi‐Qiao Sang, Zi‐Xiang Kuai   +7 more
openalex   +2 more sources