Results 21 to 30 of about 4,626,170 (385)

Neoadjuvant therapy with immune checkpoint blockade, antiangiogenesis, and chemotherapy for locally advanced gastric cancer

Nature Communications, 2023
Immune checkpoint inhibitors and antiangiogenic agents have shown some activity in patients with late-stage gastric cancer. Here the authors report the results of a phase II trial of neoadjuvant anti-PD1 (camrelizumab), antiangiogenic agent (apatinib ...
Song Li, Wenbin Yu, Fei Xie, Haitao Luo, Zhimin Liu, Weiwei Lv, Duan-Bo Shi, Dexin Yu, P. Gao, Cheng Chen, Meng Wei, Wenhao Zhou, Jiaqian Wang, Zhikun Zhao, Xin Dai, Qian Xu, Xue Zhang, Miao Huang, Kai Huang, Jian Wang, Jisheng Li, Lei Sheng, Lian Liu   +22 more
semanticscholar   +1 more source

Association between pathologic response and survival after neoadjuvant therapy in lung cancer

Nature Network Boston, 2023
Analysis of the phase 3 CheckMate 816 trial shows that the depth of pathologic response as assessed by percent residual viable tumor is correlated with event-free survival following neoadjuvant immunotherapy plus chemotherapy, supporting pathologic ...
J. Deutsch, A. Cimino-Mathews, Elizabeth Thompson, Mariano Provencio, P. Forde, Jonathan D Spicer, N. Girard, Daphne Wang, Robert A Anders, Edward Gabrielson, Peter B Illei, Jaroslaw Jedrych, Ludmila Danilova, Joel C. Sunshine, Keith M Kerr, Mia Tran, J. Bushong, Junliang Cai, V. Devas, J. Neely, D. Balli, T. Cottrell, Alexander S. Baras, Janis M. Taube   +23 more
semanticscholar   +1 more source

Neoadjuvant Therapy for Locally Advanced Esophageal Cancers

Frontiers in Oncology, 2022
Esophageal carcinoma is one of the most aggressive malignant diseases. At present, neoadjuvant chemotherapy and neoadjuvant chemoradiotherapy are regarded as the standard modalities for the treatments of locally advanced esophageal cancers based on ...
Runkai Huang, Zhenbin Qiu, Chunwen Zheng, Ruijie Zeng, Wanxian Chen, Simeng Wang, Enmin Li, Yiwei Xu, Yiwei Xu   +8 more
doaj   +1 more source

Total neoadjuvant therapy for rectal cancer: a guide for surgeons

Canadian journal of surgery. Journal canadien de chirurgie, 2023
Summary The modern management of rectal cancers continues to evolve. With the release of data from new landmark randomized controlled trials (RAPIDO, PRODIGE-23), total neoadjuvant therapy (TNT) has moved to the forefront of locally advanced rectal ...
Garrett Johnson, Jason Park, R. Helewa, B. Goldenberg, M. Nashed, E. Hyun   +5 more
semanticscholar   +1 more source

Adjuvant and neoadjuvant therapies in melanoma [PDF]

ESMO Open, 2020
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Kok Haw Jonathan Lim, Teresa Amaral
openaire   +6 more sources

Evaluation of the efficacy and surgical-related safety of neoadjuvant immunochemotherapy in advanced resectable none small cell lung cancer (NSCLC)

Frontiers in Oncology, 2023
BackgroundThe emergence of immune checkpoint inhibitors (ICIs) has brought about a paradigm shift in the treatment landscape of non-small cell lung cancer (NSCLC).
Qin Wang, Chen Qi, Jing Luo, Nan Xu, Mao-tian Xu, Yong Qiang, Chi Zhang, Yi Shen   +7 more
doaj   +1 more source

Impact on CD4+ CD25High-CD127low regulatory T (Treg) cells of neoadjuvant therapy for rectal cancer patients

Indian Journal of Pathology and Microbiology, 2023
Background: The efficacy of neoadjuvant therapy for rectal cancer has not been assessed. Objective: To evaluate proportional changes in peripheral blood immune cells in rectal cancer patients after neoadjuvant therapy and assess the relationship between ...
Liu Maoxi, Liu Haiyi
doaj   +1 more source

Neoadjuvant Chemotherapy, Endocrine Therapy, and Targeted Therapy for Breast Cancer: ASCO Guideline

Journal of Clinical Oncology, 2021
PURPOSE To develop guideline recommendations concerning optimal neoadjuvant therapy for breast cancer. METHODS ASCO convened an Expert Panel to conduct a systematic review of the literature on neoadjuvant therapy for breast cancer and provide recommended
L. Korde, M. Somerfield, L. Carey, J. Crews, N. Denduluri, E. Hwang, S. Khan, S. Loibl, E. Morris, Alejandra T. Perez, M. Regan, P. Spears, Preeti K. Sudheendra, W. Symmans, R. Yung, Brittany E. Harvey, D. Hershman   +16 more
semanticscholar   +1 more source

Androgen deprivation therapy plus apalutamide as neoadjuvant therapy prior radical prostatectomy for patients with unresectable prostate cancer

Frontiers in Pharmacology, 2023
Whether neoadjuvant therapy confers a survival benefit in advanced prostate cancer (PCa) remains uncertain. The primary endpoints of previous retrospective and phase II clinical studies that used neoadjuvant therapy, including androgen deprivation ...
Yongbao Wei, Yongbao Wei, Ruochen Zhang, Ruochen Zhang, Dewen Zhong, Zhensheng Chen, Gen Chen, Minggen Yang, Le Lin, Le Lin, Tao Li, Tao Li, Liefu Ye, Liefu Ye, Lili Chen, Lili Chen, Qingguo Zhu, Qingguo Zhu   +17 more
doaj   +1 more source

Neoadjuvant chemotherapy and trastuzumab versus neoadjuvant chemotherapy followed by post-operative trastuzumab for patients with HER2-positive breast cancer [PDF]

, 2016
Neoadjuvant chemotherapy plus trastuzumab (NCT) increases the rate of pathological complete response (pCR) and event-free survival (EFS) compared to neoadjuvant chemotherapy (NC) alone in women with HER2 positive breast cancer (BC).
Ades, Felipe, Ahmed, Riz, Asher, Rebecca, Beresford, Mark, de Azambuja, Evandro, Gojis, Ondrej, Howell, Sacha J., Januszewski, Adam, Lewanski, Conrad, Lythgoe, Daniel, MacPherson, Iain R.J., Owadally, Waheeda, Palmieri, Carlo, Riddle, Pippa, Shah, Deep, Stanley, Barbara, Yan, Kelvin   +16 more
core   +4 more sources