Results 61 to 70 of about 5,297,540 (313)

Perioperative chemotherapy in colorectal cancer with peritoneal metastases: A global propensity score matched studyResearch in context

EClinicalMedicine, 2023
Summary: Background: There is a paucity of studies evaluating perioperative systemic chemotherapy in conjunction with cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) in patients with colorectal cancer peritoneal ...
Peter H. Cashin, Jesus Esquivel, Stein G. Larsen, Winston Liauw, Nayef A. Alzahrani, David L. Morris, Vahan Kepenekian, Isabelle Sourrouille, Frédéric Dumont, Jean-Jacques Tuech, Cécilia Ceribelli, Beranger Doussot, Olivia Sgarbura, Francois Quenet, Olivier Glehen, Oliver M. Fisher   +15 more
doaj   +1 more source

Neoadjuvant Therapy for Hepatocellular Carcinoma

Journal of Hepatocellular Carcinoma, 2022
Hepatocellular carcinoma (HCC) is characterized by low resection and high postoperative recurrence rates, and conventional treatment strategies have failed to meet clinical needs.
Z. Yin, Dongying Chen, Shuang Liang, Xiaowu Li   +3 more
semanticscholar   +1 more source

Neoadjuvant anti-PD-1 immunotherapy promotes a survival benefit with intratumoral and systemic immune responses in recurrent glioblastoma. [PDF]

, 2019
Glioblastoma is the most common primary malignant brain tumor in adults and is associated with poor survival. The Ivy Foundation Early Phase Clinical Trials Consortium conducted a randomized, multi-institution clinical trial to evaluate immune responses ...
Arrillaga-Romany, Isabel C, Butowski, Nicholas A, Clarke, Jennifer L, Cloughesy, Timothy F, Cohen, Adam L, Colman, Howard, Davidson, Tom B, de Groot, John F, Du, Lin, Ellingson, Benjamin M, Gaffey, Sarah C, Hugo, Willy, Kaley, Thomas J, Kawaguchi, Eric S, Lee, Alexander H, Lee, Eudocia Q, Li, Gang, Liau, Linda M, Mellinghoff, Ingo K, Mochizuki, Aaron Y, Nghiemphu, Phioanh L, O'Brien, Barbara J, Orpilla, Joey R, Prins, Robert M, Reardon, David A, Rytlewski, Julie A, Sanders, Catherine M, Wang, Anthony C, Wen, Patrick Y, Yong, William H   +29 more
core  

Preoperative Management of Locally Advanced Rectal Cancer and the Role of Restaging MRI: An Australasian Perspective

World Journal of Colorectal Surgery, 2020
Background: Major advances in the management of locally advanced rectal cancer has led to controversies and varying clinical practices among colorectal surgeons, such as patient selection for neoadjuvant therapy and preferred regimen for neoadjuvant ...
Milton Mui, Joseph C. Kong, Glen R. Guerra, Alexander G. Heriot   +3 more
doaj   +1 more source

Neoadjuvant therapy for pancreatic cancer

Updates in Surgery, 2021
Multimodal treatment including surgery and chemotherapy is considered the gold standard treatment of pancreatic cancer by most guidelines. Neoadjuvant therapy (NAT) has been seen as a possible treatment option for resectable, borderline resectable and ...
J. Gugenheim, A. Crovetto, N. Petrucciani   +2 more
semanticscholar   +1 more source

Outcomes and Surgical Management of Malignant Rhabdoid Tumor of the Kidney: A Report From the Pediatric Surgical Oncology Research Collaborative

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Malignant rhabdoid tumor of the kidney (MRTK) is a rare, aggressive tumor seen in young children. The optimal timing of resection for locally advanced tumors is not well‐defined. The purpose of this study is to evaluate modern oncologic outcomes and the impact of surgical timing. Methods A multicenter retrospective review was performed
Hannah N. Rinehardt, Elisabeth T. Tracy, Anghela Paredes, Catherine Beckhorn, Harold J. Leraas, Joseph Fusco, Katlyn G. McKay, Nelly‐Ange T. Kontchou, Zachary J. Kastenberg, David W. Hoyt, Jonathan Roach, Emily K. Myers, Nicholas G. Cost, Bhargava Mullapudi, Charles R. Marchese, Amanda R. Jensen, Timothy B. Lautz, Michela Carter, Roshni Dasgupta, John Lundstedt, Joseph G. Brungardt, Lindsay Talbot, Andrew M. Davidoff, Andrew J. Murphy, Jennifer H. Aldrink, Sara Mansfield, Nelson Piche, Annie Le‐Nguyen, Dave R. Lal, Brian T. Craig, Jennifer M. Schuh, Barrett P. Cromeens, Sindhu Mannava, Shannon Castle, Adriana Lopez, Kelsey Mello, Joshua Short, Robin T. Petroze, Shay Rajaval, Grace R. Thompson, Peter Mattei, David H. Rothstein, Elizabeth Fialkowski, Kathryn Fowler, Nathan Martchenke, Barrie S. Rich, Richard D. Glick, Erin G. Brown, Kathleen Doyle, Paige Abril, Natashia Seemann, Jacob Davidson, Claire A. Wilson, Hau D. Le, Devashish Joshi, Michael Stellon, Tamer Ahmed, Alexandra Dimmer, Peter F. Ehrlich, Maya Hammoud, Keyonna Williams, Christa N. Grant, Merit Gorgy, Stephanie F. Polites, Julia Debertin, Danielle B. Cameron, Alyssa Stetson, Eugene S. Kim, William G. Lee, Aaron Barkhordar, Mary Austin, Brian A. Coakley, Anastasia Kahan, Joseph T. Murphy, Michael Pitonak, Chloé Boehmer, Marcus M. Malek   +76 more
wiley   +1 more source

F-18-FDG and C-11-choline positron emission tomography in human esophago-gastric cancer : prediction of response to therapy [PDF]

, 2010
Peer reviewedPublisher ...
Hammonds, Solveig, McAteer, Dympna, Nicolson, Marianne, Park, Kenneth, Schweiger, Lutz, Sheehan, Margaret, Smith, Timothy, Suttie, Stuart, Welch, Andrew   +8 more
core   +1 more source

Neoadjuvant therapy induces a potent immune response to sarcoma, dominated by myeloid and B cells.

Clinical Cancer Research, 2022
PURPOSE To characterize changes in the soft tissue sarcoma tumor immune microenvironment induced by standard neoadjuvant therapy with the goal of informing neoadjuvant immunotherapy trial design.
P. Goff, Laura Riolobos, B. LaFleur, M. Spraker, Y. D. Seo, K. Smythe, J. Campbell, R. Pierce, Yuzheng Zhang, Qianchuan He, Edward Y. Kim, S. Schaub, G. Kane, J. Mantilla, E. Chen, R. Ricciotti, Mathew J Thompson, L. Cranmer, M. Wagner, E. Loggers, Robin L. Jones, E. Murphy, W. Blumenschein, T. Mcclanahan, J. Earls, K. Flanagan, N. LaFranzo, Teresa S. Kim, S. Pollack   +28 more
semanticscholar   +1 more source

MYCN Amplification in RB1‐Inactivated Retinoblastoma: Association With High‐Risk Features

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background MYCN amplification occurs in a subset of retinoblastoma cases, both with and without RB1 inactivation. It has been suggested that retinoblastomas with MYCN amplification represent a distinct entity with more aggressive clinical behavior.
Kyriaki Papaioannou, Regina Kubica, Karen Fischhuber, Jasmin Beygo, Madlen Reschke, Petra Ritter‐Sovinz, Eva Biewald, Petra Ketteler, Dietmar Lohmann, Deniz Kanber   +9 more
wiley   +1 more source

DCE-MRI and parametric imaging in monitoring response to neoadjuvant chemotherapy in breast carcinoma : a preliminary report [PDF]

, 2018
Purpose: Neoadjuvant chemotherapy is recommended in patients with locally advanced breast cancer. Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) enables evaluation of the tumour neovasculature that occurs prior to any volume change, which
Fotedar, Vikas, Seam, Rajeev K., Sharma, Anjna, Sharma, Mukesh, Sharma, Sanjiv, Sood, Shikha   +5 more
core   +1 more source