zic-1 Expression in Planarian neoblasts after injury controls anterior pole regeneration. [PDF]
PLoS Genetics, 2014 Mechanisms that enable injury responses to prompt regenerative outgrowth are not well understood. Planarians can regenerate essentially any tissue removed by wounding, even after decapitation, due to robust regulation of adult pluripotent stem cells of ...
Constanza Vásquez-Doorman +1 more
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Decoding Stem Cells: An Overview on Planarian Stem Cell Heterogeneity and Lineage Progression [PDF]
Biomolecules, 2021 Planarians are flatworms capable of whole-body regeneration, able to regrow any missing body part after injury or amputation. The extraordinary regenerative capacity of planarians is based upon the presence in the adult of a large population of somatic ...
M. Dolores Molina, Francesc Cebrià
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Transcriptional signatures of somatic neoblasts and germline cells in Macrostomum lignano
eLife, 2016 The regeneration-capable flatworm Macrostomum lignano is a powerful model organism to study the biology of stem cells in vivo. As a flatworm amenable to transgenesis, it complements the historically used planarian flatworm models, such as Schmidtea ...
Magda Grudniewska +9 more
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Poly (A) binding protein 2 is critical for stem cell differentiation during regeneration in the planarian Schmidtea mediterranea [PDF]
Frontiers in Cell and Developmental BiologyPost-transcriptional regulation has emerged as a key mechanism for regulating stem cell renewal and differentiation, which is essential for understanding tissue regeneration and homeostasis.
Namita Mukundan +8 more
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A transcription factor atlas of stem cell fate in planarians [PDF]
Cell ReportsSummary: Whole-body regeneration requires the ability to produce the full repertoire of adult cell types. The planarian Schmidtea mediterranea contains over 125 cell types, which can be regenerated from a stem cell population called neoblasts.
Hunter O. King +3 more
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Mining differentially expressed genes during paratomy in the transcriptome of the flatworm Stenostomum leucops [PDF]
Scientific ReportsParatomy is an asexual reproductive process that occurs in annelids, flatworms and other groups. During this process, anterior structures are formed in the middle of the body, giving rise to segmented organisms, each segment being called a zooid.
Marcos Trindade da Rosa +1 more
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PLoS Pathogens, 2018 While schistosomiasis remains a significant health problem in low to middle income countries, it also represents a recently recognised threat to more economically-developed regions.
Kathrin K Geyer +5 more
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Open Biology, 2023 Adult planarians can regenerate the gut, eyes and even a functional brain. Proper identity and patterning of the newly formed structures require signals that guide and commit their adult stem cells.
M. Dolores Molina +4 more
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Regeneration of Planarian Auricles and Reestablishment of Chemotactic Ability
Frontiers in Cell and Developmental Biology, 2021 Detection of chemical stimuli is crucial for living systems and also contributes to quality of life in humans. Since loss of olfaction becomes more prevalent with aging, longer life expectancies have fueled interest in understanding the molecular ...
Eugene Matthew P. Almazan +3 more
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Melt-enhanced strain localization and phase mixing in a large-scale mantle shear zone (Ronda peridotite, Spain) [PDF]
Solid Earth, 2023 Strain localization in upper-mantle shear zones by grain size reduction and the activation of grain-size-sensitive deformation mechanisms is closely linked to phase mixing.
S. Tholen +3 more
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