Results 31 to 40 of about 1,635 (162)
Frontiers in Cellular and Infection Microbiology, 2023 BackgroundTapeworm larvae cause important diseases in humans and domestic animals. During infection, the first larval stage undergoes a metamorphosis where tissues are formed de novo from a population of stem cells called germinative cells.
Jimena Montagne +2 more
doaj +1 more source
Tissue Degeneration following Loss of Schistosoma mansoni cbp1 Is Associated with Increased Stem Cell Proliferation and Parasite Death In Vivo. [PDF]
PLoS Pathogens, 2016 Schistosomiasis is second only to malaria in terms of the global impact among diseases caused by parasites. A striking feature of schistosomes are their ability to thrive in their hosts for decades. We have previously demonstrated that stem cells, called
Julie N R Collins, James J Collins
doaj +1 more source
Biology, 2023 We have studied the effect of two glucocorticoid hormones: hydrocortisone and its synthetic analogue methylprednisolone on the regeneration activity of head and tail blastema of the Girardia tigrina planarian.
Artem Ermakov +3 more
doaj +1 more source
Transcriptome analysis reveals strain-specific and conserved stemness genes in Schmidtea mediterranea. [PDF]
PLoS ONE, 2012 The planarian Schmidtea mediterranea is a powerful model organism for studying stem cell biology due to its extraordinary regenerative ability mediated by neoblasts, a population of adult somatic stem cells. Elucidation of the S.
Alissa M Resch +4 more
doaj +1 more source
Pharmaceutics, 2023 Djeya1 (RKLAFRYRRIKELYNSYR) is a very effective cell penetrating peptide (CPP) that mimics the α5 helix of the highly conserved Eya domain (ED) of eyes absent (Eya) proteins.
Sarah Jones +4 more
doaj +1 more source
The regenerative flatworm Macrostomum lignano, a model organism with high experimental potential [PDF]
, 2018 Understanding the process of regeneration has been one of the longstanding scientific aims, from a fundamental biological perspective, as well as within the applied context of regenerative medicine.
Berezikov, Eugene +3 more
core +5 more sources
eLife, 2022 Planarians have become an established model system to study regeneration and stem cells, but the regulatory elements in the genome remain almost entirely undescribed. Here, by integrating epigenetic and expression data we use multiple sources of evidence
Jakke Neiro +3 more
doaj +1 more source
Flow Cytometry Analysis of Planarian Stem Cells Using DNA and Mitochondrial Dyes
Bio-Protocol, 2022 Planarians are free-living flatworms that emerged as a crucial model system to understand regeneration and stem cell biology. The ability to purify neoblasts, the adult stem cell population of planaria, through fluorescence-activated cell sorting (FACS ...
Mohamed Mohamed Haroon +2 more
doaj +1 more source
The CCR4-NOT complex mediates deadenylation and degradation of stem cell mRNAs and promotes planarian stem cell differentiation. [PDF]
PLoS Genetics, 2013 Post-transcriptional regulatory mechanisms are of fundamental importance to form robust genetic networks, but their roles in stem cell pluripotency remain poorly understood.
Jordi Solana +7 more
doaj +1 more source
DNA damage and tissue repair: What we can learn from planaria. [PDF]
, 2019 Faithful renewal of aging and damaged tissues is central to organismal lifespan. Stem cells (SCs) generate the cellular progeny that replenish adult tissues across the body but this task becomes increasingly compromised over time. The age related decline
Barghouth, Paul G +3 more
core +1 more source