Results 61 to 70 of about 1,704 (212)

Eye Absence Does Not Regulate Planarian Stem Cells during Eye Regeneration [PDF]

, 2018
Dividing cells called neoblasts contain pluripotent stem cells and drive planarian flatworm regeneration from diverse injuries. A long-standing question is whether neoblasts directly sense and respond to the identity of missing tissues during ...
Adler, Adler, Amamoto, Baguñà, Benian, Cebrià, Cowles, Currie, Dubois, Forsthoefel, Guo, Gurley, Hsu, King, Lapan, Lapan, Mangel, Marz, Newmark, Nishimura, Pearson, Pellettieri, Peter W. Reddien, Petersen, Petersen, Poss, Reddien, Reddien, Reddien, Rouhana, Samuel A. LoCascio, Schindelin, Scimone, Scimone, Scimone, Scimone, Sylvain W. Lapan, Sánchez Alvarado, Sánchez Alvarado, Sánchez Alvarado, Tanaka, van Wolfswinkel, Wagner, Wagner, Wenemoser, Witchley   +45 more
core   +1 more source

The Employment of Hydrogen Peroxide in Water Disinfection Poses a Threat to Aquatic Ecosystems Because of Its Toxicity to Nontarget Organisms

Environmental Toxicology, EarlyView.
ABSTRACT Hydrogen peroxide is widely used in water and wastewater treatment, particularly in advanced oxidation processes that aid in the degradation of compounds and microbial disinfection. Despite concerns about potential environmental contamination, its impact on freshwater ecosystems remains inadequately studied.
Letícia Queiroz Almeida, Thayrine Dias Carlos, Leydiane Barbosa Bezerra, Rone S. Barbosa, Nelson Luís Gonçalves Dias Souza, Douglas Henrique Pereira, Renato Almeida Sarmento, Grasiele Soares Cavallini   +7 more
wiley   +1 more source

Fraternal cooperation of hierarchical cancer parallels metazoan multicellularity and eusociality

Biological Reviews, Volume 101, Issue 1, Page 400-418, February 2026.
ABSTRACT Metazoan multicellularity and eusociality — both outcomes of the fraternal major transitions — have numerous features in common such as uneven distribution of group‐establishing potential. In addition to this framework, I argue herein that the group‐forming principles of metazoan multicellularity and eusociality are analogous to hierarchical ...
Jibeom Choi
wiley   +1 more source

Flatworm-specific transcriptional regulators promote the specification of tegumental progenitors in Schistosoma mansoni

eLife, 2018
Schistosomes infect more than 200 million people. These parasitic flatworms rely on a syncytial outer coat called the tegument to survive within the vasculature of their host.
George R Wendt, Julie NR Collins, Jimin Pei, Mark S Pearson, Hayley M Bennett, Alex Loukas, Matthew Berriman, Nick V Grishin, James J Collins III   +8 more
doaj   +1 more source

SUMOylation controls stem cell proliferation and regional cell death through Hedgehog signaling in planarians. [PDF]

, 2017
Mechanisms underlying anteroposterior body axis differences during adult tissue maintenance and regeneration are poorly understood. Here, we identify that post-translational modifications through the SUMO (Small Ubiquitin-like Modifier) machinery are ...
Barghouth, Paul G, Broday, Limor, Oviedo, Néstor J, Thiruvalluvan, Manish, Tsur, Assaf   +4 more
core   +1 more source

Regenerate to “Rejuvenate”: Insights From Adult Resident Stem Cells of Aged Flatworms and Mice

Aging Cell, Volume 24, Issue 11, November 2025.
Resident stem cells from aged planaria and murine skeletal muscle possess some inherent abilities to mitigate signs of aging after tissue regeneration. ABSTRACT Adult resident stem cells are capable of regenerating tissues that manifest signs of “rejuvenation” in flatworms and mice of older ages.
Kevin A. Murach, Cory M. Dungan, Toby L. Chambers, Steve Horvath, Jayakrishnan Nandakumar, Vadim N. Gladyshev, Scott D. Pletcher, Xiaoting Dai, Longhua Guo   +8 more
wiley   +1 more source

Single-Cell Analysis Reveals Functionally Distinct Classes within the Planarian Stem Cell Compartment [PDF]

Planarians are flatworms capable of regenerating any missing body region. This capacity is mediated by neoblasts, a proliferative cell population that contains pluripotent stem cells.
Reddien, Peter, van Wolfswinkel, Josien C., Wagner, Daniel E.   +2 more
core   +1 more source

Planarian Epidermal Stem Cells Respond to Positional Cues to Promote Cell-Type Diversity [PDF]

, 2017
Successful regeneration requires that progenitors of different lineages form the appropriate missing cell types. However, simply generating lineages is not enough.
Oderberg, Isaac Max, Reddien, Peter, Wurtzel, Omri   +2 more
core   +1 more source

Fluid or Melt? Distinguishing Syn‐Deformational Interaction Pathways

Journal of Metamorphic Geology, Volume 43, Issue 8, Page 810-838, October 2025.
ABSTRACT Understanding whether deformation occurred in the presence of aqueous fluid or silicate melt is crucial for interpreting ductile shear zones, impacting their thermal and geochemical evolution, and having rheological consequences. To identify the syn‐deformational fluid type, we investigate contrasting shear zones active during the Alice ...
Hindol Ghatak, Nathan R. Daczko, Sandra Piazolo, Tom Raimondo   +3 more
wiley   +1 more source

Reduced Adult Neurogenesis in Humans Results From a Tradeoff Rather Than Direct Negative Selection

BioEssays, Volume 47, Issue 9, September 2025.
Embryonic radial glia (RG) generate neurons, glial cells, and later adult neural stem cells, which sustain adult neurogenesis (top, left to right). Human‐specific genetic modifications (blue arrow), selected to boost early RG neurogenic activity, may lead to premature RG exhaustion and reduced adult neurogenesis in the human brain (bottom).
David Morizet, Laure Bally‐Cuif
wiley   +1 more source