Results 141 to 150 of about 691,594 (323)
Overview of the regulation of intrinsic and extrinsic signals during neurodevelopment. Intrinsic genetic signals from NSCs, in conjunction with cues from microglia and blood vessels, collaboratively regulate the proliferation of NSCs, their fate determination, synaptogenesis, synaptic pruning, neuronal survival, and death, as well as communication ...
Yanyan Wang+4 more
wiley +1 more source
New research reveals that oxytocin signaling during the early postnatal period is critical for regulating brain development and social behavior. Selectively suppressing oxytocin neurons by chemogenetic method shows that early—but not late—disruption leads to autism‐like behaviors.
Zi‐Hui Wang+10 more
wiley +1 more source
Aided by FABP5, abnormally elevated asprosin in hepatocytes enters the nucleus, targets and inhibits PPARα binding to the CPT1A promoter, thereby suppressing FAO. Circulating asprosin exacerbates insulin resistance, collectively driving MASLD progression.
Yuan‐Yuan Yu+13 more
wiley +1 more source
Collodion Skin in the Neonate due to Lamellar Ichthyosis [PDF]
H. V. L. Finlay, J. P. Bound
openalex +1 more source
Die neonatale eenheid behoort só beplan te wees dat dit onnodige toegang uitskakel. Dit behoort verskillende versorgingsafdelings te he om vir verskillende vlakke intensiewe verpleegsorg voorsiening te maak. Gespesialiseerde sorg word verkieslik in ’n groot enkelkamer verskaf, maar opnames in die afdeling behoort eers in ’n afsonderlike kamer aandag te
openaire +4 more sources
RACK7 Interacts with PRC2 Complex to Regulate Astrocyte Development
The study investigates the role of RACK7 in brain development using a conditional knockout mouse model. RACK7 deficiency results in developmental defects and abnormal astrocyte development by disrupting H3K27me3 chromatin binding. The underlying mechanism involves RACK7 interacting with the PRC2 complex to regulate the genomic localization of SUZ12 and
Fangfang Jiao+9 more
wiley +1 more source
Neonatal Ascites Associated with Urethral Obstruction [PDF]
N. E. France, Erik Bäck
openalex +1 more source
Cardiomyocyte‐enriched USP20 regulates the K63‐linked ubiquitination of STAT3, and the cardiomyocyte‐specific USP20‐STAT3‐CARM1 axis exerts a protective role in cardiac hypertrophy. Targeting USP20 through cardiac‐specific gene therapy presents a promising strategy for the treatment of cardiac hypertrophy.
Lingfeng Zhong+15 more
wiley +1 more source