Results 171 to 180 of about 691,594 (323)
Dipyridamole Acts as Clinical Ferroptosis Inhibitor to Prevent from Tissue Injury
Advanced Science, EarlyView.Dipyridamole acts as a clinically used compound to suppress ferroptosis. Dipyridamole down‐regulates the expression of RNF126, which is an E3 ligase to ubiquitinate SLC7A11 for proteasome degradation. The deficiency of SLC7A11 largely abolishes the protective role of dipyridamole both in vitro and in vivo.
Xiao Zhuang +22 more
wiley +1 more source
Pancreatic Extract in Neonatal Treatment of Meconium Ileus: Report of a case. [PDF]
, 1969 Norman G. Kirby, B. H. Valentine
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The Role of MCPIP1 in Macrophage Polarization and Cardiac Function Post‐Myocardial Infarction
Advanced Science, EarlyView.Following myocardial infarction, MCPIP1 deficiency in macrophages triggers ferroptosis, driving proinflammatory M1 dominance over reparative M2 phenotypes. This imbalance amplifies splenic monocyte release and sustains cardiac inflammation. Concurrently, excessive inflammatory mediators and insufficient TGF‐β impair fibroblast activation, delaying ...
Xingxu Zhang +8 more
wiley +1 more source
Advanced Science, EarlyView.The FGF13 level is significantly downregulated in premature aging murine hearts subject to D‐galactose and Doxorubicin. FGF13 overexpression and deficiency exacerbated and alleviated Doxorubicin/D‐galactose‐induced myocardial aging characteristics and functional impairment, respectively.
Enzhao Shen +15 more
wiley +1 more source
A computed tomography‐based survey of paramedullary diverticula in extant Aves
The Anatomical Record, Volume 306, Issue 1, Page 29-50, January 2023., 2023 Abstract Avian respiratory systems are comprised of rigid lungs connected to a hierarchically organized network of large, regional air sacs, and small diverticula that branch from them. Paramedullary diverticula are those that rest in contact with the spinal cord, and frequently invade the vertebral canal.
Jessie Atterholt, Mathew J. Wedel
wiley +1 more source
Advanced Science, EarlyView.The aldehyde‐ and catechol‐modified starch (ACS) microparticle (MP) is developed by chemical modifications and freeze‐milling after calcium intercalation for highly absorbent and tissue‐adhesive properties. The ACS‐MP can be self‐gelled upon contact with biological fluids and blood on tissue surfaces, rapidly absorbing them and achieving robust wet ...
Soohwan An +7 more
wiley +1 more source
Morphologies in‐between: The impact of the first steps on the human talus
The Anatomical Record, Volume 306, Issue 1, Page 124-142, January 2023., 2023 Abstract Objective The development of bipedalism is a very complex activity that contributes to shaping the anatomy of the foot. The talus, which starts ossifying in utero, may account for the developing stages from the late gestational phase onwards.
Carla Figus +21 more
wiley +1 more source
South African journal of surgery. Suid-Afrikaanse tydskrif vir chirurgie, 2011 Until recently minimally invastive surgery was not performed in neonates. This was because of their small size and distinct physiological characteristics, neonates were not operated on using minimally invasive surgery until recently. Since the introduction of fine laparoscopic instruments, improvements in the surgical techniques and anaesthetic ...
Numanoglu, Alp, Alexander, Angus
openaire +3 more sources