Results 191 to 200 of about 1,924,739 (391)

A vitamin K prophylaxis survey among breastfeeding mothers [PDF]

, 2014
A survey was distributed among new breastfeeding mothers in northern England to gain insight into their experiences with different forms of neonatal vitamin K prophylaxis.
Haining, Shona, Howlett, Helen, Limerick, Siobhan, Matthias Strehle, Eugen, Norman, Justine   +4 more
core   +1 more source

Identifying Myeloid‐Derived Suppressor Cells and Lipocalin‐2 as Therapeutic Targets for Intervertebral Disc Degeneration

Advanced Science, EarlyView.
Inflammatory dysregulation drives intervertebral disc degeneration via stage‐dependent immune cellular dynamics. Single‐cell transcriptomics and genetic risk mapping revealed a shift from LCN2high myeloid‐derived suppressor cells maintaining disc repair in early stages to IL1B+ macrophage‐dominated pathology in advanced disease.
Changmeng Zhang, Haoyun Li, Hongfei Wang, Liangyu Shi, Ying Shing Chan, Yu Wang, Graham Ka Hon Shea   +6 more
wiley   +1 more source

Paving the way in implementation of SCID newborn screening in developing nations: feasibility study and strategies to move forward in Malaysia

Frontiers in Immunology
Early diagnosis and effective management of Primary immunodeficiency diseases (PIDs), particularly severe combined immunodeficiency (SCID), play a crucial role in minimizing associated morbidities and mortality.
Gaayathri Kumarasamy, Khayrin Khairiz, Wai Leng Chang, Wai Leng Chang, Thin Thin Aye, Adli Ali, Adli Ali, Adli Ali, Adli Ali   +8 more
doaj   +1 more source

Hypoxia-inducible factor: role in cell survival in superoxide dismutase overexpressing mice after neonatal hypoxia-ischemia. [PDF]

, 2019
BackgroundSixty percent of infants with severe neonatal hypoxic-ischemic encephalopathy die, while most survivors have permanent disabilities. Treatment for neonatal hypoxic-ischemic encephalopathy is limited to therapeutic hypothermia, but it does not ...
Ferriero, Donna M, Jeon, Ga Won, Sheldon, R Ann   +2 more
core  

Neonatal Bact. coli Meningitis [PDF]

, 1948
H. R. Duval, J. T. Burrowes
openalex   +1 more source

Inhibition of Phosphodiesterase 10A by MP‐10 Rescues Behavioral Deficits and Normalizes Microglial Morphology and Synaptic Pruning in A Mouse Model of FOXP1 Syndrome

Advanced Science, EarlyView.
We demonstrate that Foxp1± mice, modeling FOXP1 haploinsufficiency, exhibit behavioral deficits, striatal neuroinflammatory changes including altered microglial complexity and synaptic pruning, and markedly reduced Pde10a expression. Pde10a inhibition starting immediately after birth restores Foxp1± behavior, microglial morphology, and pruning ...
Henning Fröhlich, Jing Wang, Ferdinand Althammer, Tim Schubert, Nina Kluck, Valery Grinevich, Stefanie Schmitteckert, Christian P. Schaaf, Gudrun A. Rappold   +8 more
wiley   +1 more source

Statistical models of economic burden : a case study in medicine [PDF]

, 2019
Purpose: The main aim of this article is to use statistical methods for the estimation of the economic burden and the survival rate of deeply premature babies.
Gindullin, R. V., Lakman, I. A., Maksimenko, Z. V., Shangareeva, R. Kh.   +3 more
core  

Neonatal Response to DTP Vaccines [PDF]

, 1958
Laszlo Goerke, P Roberts, John Chapman
openalex   +1 more source

Gut Metabolite Indole‐3‐Propionic Acid Regulates Macrophage Autophagy Through PPT1 Inhibiting Aging‐Related Myocardial Fibrosis

Advanced Science, EarlyView.
IPA is an intestinal tryptophan metabolite whose effects decline with decreased heart function. Supplementing IPA can alleviate the aging‐related myocardial fibrosis through PPT1. PPT1 is a key protein localized to lysosomes, and IPA can restore macrophage autophagy function by regulating PPT1 expresssions, thereby reducing aging‐related myocardial ...
Jing Lu, Hongyan Wang, Haiyu Zhang, Jiahao Li, Hanqi Li, Qiuyu Chen, Dongyu Han, Jialiang Liu, Lin Lv, Jie Xiong, Keying Yuan, Xianpeng Wei, Siqi Sheng, Fukai Liu, Yuanqi Shi, Zengxiang Dong, Yue Li   +16 more
wiley   +1 more source

Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine

Advanced Science, EarlyView.
Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang, Feng Gao, Liqun Yu, Haokun Chen, Rongrong Zhu   +4 more
wiley   +1 more source