Results 201 to 210 of about 1,240,539 (312)

Zebrafish and CRISPR—A synergistic approach to decipher and cure human diseases

Animal Models and Experimental Medicine, EarlyView.
Zebrafish, with high genetic homology to humans, serves as a powerful vertebrate model for disease modeling and drug discovery. Integration of CRISPR/Cas9 technology enables precise genome editing, facilitating the development of translational models for human diseases.
Manikandan Sivaprakasam, Aashika Raagavi Jeanpierre, Salma Mohammed, Rajesh Srinivasan, Aman Kumar Mohanty   +4 more
wiley   +1 more source

Neonatal Hypoglycemia: A Systematic Review of International and Local Clinical Guidelines with Clinical Implications. [PDF]

J Clin Med
Rusu C, Matyas M, Kramer BW, Dorobanțu FR, Bodog A.   +4 more
europepmc   +1 more source

The neonatal eye [PDF]

Eye, 1992
openaire   +2 more sources

Stem cell–based therapies for type 1 diabetes: Progress in differentiation, clinical translation, and immune protection

Animal Models and Experimental Medicine, EarlyView.
Directed differentiation of pluripotent stem cells into functional pancreatic β cells have emerged as a promising strategy for the radical treatment of type 1 diabetes, with preclinical and early clinical evidence demonstrating reversal of hyperglycemia and insulin independence.
Zifan Li, Yu Kang, Yuyu Niu
wiley   +1 more source

HIF-1α Promotes Macrophage Extracellular Trap Formation and Exacerbates Acute Lung Injury in Neonatal Sepsis. [PDF]

Biomedicines
Zhang H, Huang W, Dai X, Zheng J, Jiang X, Yang Y, Zhong H, Yang G.   +7 more
europepmc   +1 more source

Revertant Mosaicism Obscures Long‐Awaited Molecular Confirmation of Diamond‐Blackfan Anemia

American Journal of Medical Genetics Part A, EarlyView.
Nicholas A. Borja, Mustafa Tekin
wiley   +1 more source

Recent advances in the construction of humanized animal models and applications in translational medicine

Animal Models and Experimental Medicine, EarlyView.
Substantial advances have been achieved in the development of humanized mouse models, which have proven highly valuable in evaluating cancer immunotherapies and elucidating the mechanisms of infectious diseases. There is now a growing shift in research toward larger animal models—such as pigs—that offer greater physiological similarity to humans ...
Yanan Lyu, Yong‐Guang Yang, Zheng Hu
wiley   +1 more source

Placental pathology and maternal risk factors as predictors of adverse neonatal outcomes in small-for-gestational-age births: A prospective cohort study in Northern Uganda. [PDF]

SAGE Open Med
Fahma AA, Ishimwe MPS, Kasujja M, Okello M, Kajabwangu R, Nteziyaremye T, Isse SAS, Okurut E, Mohamed AA, Ebaid AA, Ahmed EM, Araba Rajab BA, Hakizimana T.   +12 more
europepmc   +1 more source

Canine brachycephalic obstructive airway syndrome as a model for studying the effects of obstructive sleep apnea during pregnancy

Animal Models and Experimental Medicine, EarlyView.
We observed a negative effect of brachycephalic obstructive airway syndrome (BOAS) in a staggered manner based on the severity of the condition on respiratory and cardiac patterns, glycemia, acid–base balance, fetal growth, and uterine artery hemodynamics, thus requiring adaptations within the fetal–placental unit. Severely affected bitches had uterine
Roberto Rodrigues da Rosa Filho, Thayná Pantoja Gardés, Maíra Morales Brito, Leticia Lima de Almeida, Camila Infantosi Vannucchi   +4 more
wiley   +1 more source

Perinatal outcomes in pregnancies with one abnormal oral glucose tolerance test value: a retrospective cohort study. [PDF]

J Turk Ger Gynecol Assoc
Ismayilov T, Ateş Ç, Kubat Küçükyurt A.   +2 more
europepmc   +1 more source