Results 71 to 80 of about 691,594 (323)

“Therapies Through Gut:” Targeted Drug Delivery for Non‐Gastrointestinal Diseases by Oral Administration

open access: yesAdvanced Healthcare Materials, EarlyView.
Schematic illustration of the mechanism of targeted delivery of nanoparticles including 1) paracellular, 2) endolysosomal escape, 3) receptor mediated endocytosis, and 4) M cell mediated transport for non‐GI diseases by oral administration such as atherosclerosis, cancer, diabetes, and brain diseases. Abstract Oral drug delivery is a promising approach
Subarna Ray   +2 more
wiley   +1 more source

Car Seat Challenge Test in the Neonatal Intensive Care Unit

open access: yesJournal of Pediatric and Neonatal Individualized Medicine, 2019
Background: In Portugal, there is a Guideline of the Directorate General of Health that requires that newborns with hospital discharge should be transported home in a proper and safe restraint system, aligned with AAP policy statements.
Ana Brás   +5 more
doaj   +1 more source

Engineering Assembloids to Mimic Graft‐Host Skeletal Muscle Interaction

open access: yesAdvanced Healthcare Materials, EarlyView.
This study develops a graft‐host skeletal muscle assembloid model combining neuromuscular organoids with tissue‐engineered constructs. Pre‐seeding decellularized muscles with myogenic cells enhances cell migration and axon invasion from the organoid. The model exhibits regenerative capacity following acute damage, advancing the understanding of human ...
Lucia Rossi   +13 more
wiley   +1 more source

Helping small babies survive: an evaluation of facility-based Kangaroo Mother Care implementation progress in Uganda

open access: yesThe Pan African Medical Journal, 2014
INTRODUCTION: Prematurity is the leading cause of newborn death in Uganda, accounting for 38% of the nation's 39,000 annual newborn deaths. Kangaroo mother care is a high-impact; cost-effective intervention that has been prioritized in policy in Uganda ...
Patrick Aliganyira   +5 more
doaj   +1 more source

Dietary alpha-Lipoic Acid Alters Piglet Neurodevelopment

open access: yesFrontiers in Pediatrics, 2016
Introduction: Alpha-lipoic acid (a-LA) is an antioxidant shown to ameliorate age-associated impairments of brain and cardiovascular function. Human milk is known to have high antioxidant capacity, however the role of antioxidants in the developing brain ...
Austin T Mudd   +7 more
doaj   +1 more source

Mathematical modelling indicates that lower activity of the haemostatic system in neonates is primarily due to lower prothrombin concentration [PDF]

open access: yes, 2018
Haemostasis is governed by a highly complex system of interacting proteins. Due to the central role of thrombin, thrombin generation and specifically the thrombin generation curve (TGC) is commonly used as an indicator of haemostatic activity. Functional characteristics of the haemostatic system in neonates and children are significantly different ...
arxiv   +1 more source

NRTS: A Client-Server architecture for supporting data recording, transmission and evaluation of multidisciplinary teams during the neonatal resuscitation simulation scenario [PDF]

open access: yesarXiv, 2023
In this technical report, we describe Neonatal Resuscitation Training Simulator (NRTS), an Android mobile app designed to support medical experts to input, transmit and record data during a High-Fidelity Simulation course for neonatal resuscitation. This mobile app allows one to automatically send all the recorded data from "Neonatal Intensive Care ...
arxiv  

Bioprinting Perfusable and Vascularized Skeletal Muscle Flaps for the Treatment of Volumetric Muscle Loss

open access: yesAdvanced Healthcare Materials, EarlyView.
Volumetric muscle loss (VML) due to trauma or surgery, often leads to physical impairments. Traditional treatments rely on autologous flaps, limited by muscle availability often leading to donor site morbidity. This study presents multimodal bioprinting as an innovative approach for fabricating vascularized muscle flaps with 3D‐printed macrovessels ...
Eliana O. Fischer   +8 more
wiley   +1 more source

GABA Measurement in a Neonatal Fragile X Syndrome Mouse Model Using 1H-Magnetic Resonance Spectroscopy and Mass Spectrometry

open access: yesFrontiers in Molecular Neuroscience, 2020
Fragile X syndrome (FXS) is the leading monogenetic cause of autism spectrum disorder and inherited cause of intellectual disability that affects approximately one in 7,000 males and one in 11,000 females.
Samantha T. Reyes   +8 more
doaj   +1 more source

Neonatal leukaemia [PDF]

open access: yesBritish Journal of Haematology, 2018
SummaryNeonatal leukaemia is defined as occurring within the first 28 days of life and most, if not all, cases are congenital. With the exception of Down syndrome‐associated transient abnormal myelopoiesis, which is not considered here, neonatal leukaemias are rare.
Irene Roberts   +3 more
openaire   +4 more sources

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