Results 81 to 90 of about 1,938,552 (387)

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

FEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile, Daniela Ratto, Giorgia Rastelli, Ottavia Eleonora Ferraro, Caterina Temporini, Sunil Kumar, Simona Boncompagni, Paola Rossi, Monica Canepari   +8 more
wiley   +1 more source

FAKTOR­-FAKTOR RISIKO TERJADINYA ASFIKSIA NEONATORUM DI RSD JOMBANG PERIODE 1 JANUARI ­- 31 DESEMBER 2007 [PDF]

, 2009
Neonatal Asphyxia is an emergency condition when the baby failed to breath spontaneously and regularly after they were born. Neonatal asphyxia remains the main cause of neonatal mortality as well as permanent neurological abnormality.
SUNDARI TIKA, TRI
core  

A Neonate with Worms [PDF]

Clinical Infectious Diseases, 2008
Diagnosis: Dipylidium caninum infection. The sample tapeworm was M cm in length and was longer than it was wide (figure 1). On examination in the microbiology laboratory, it was determined that the segment was most consistent with D. caninum. Both the patient and his brother were treated with single doses of oral praziquantel (10 mg/kg).
Martin E. Weisse, Kathryn Moffett, Philip A. Mackowiak, Jeffrey K. Mullins   +3 more
openaire   +4 more sources

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

Molecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li, Zhijie Cao, Haiyan Xing, Zhenya Xue, Wenbing Liu, Jiayuan Chen, Yihan Mei, Runxia Gu, Hui Wei, Shaowei Qiu, Min Wang, Qing Rao, Jianxiang Wang   +12 more
wiley   +1 more source

Blocking the voltage‐gated sodium channel hNav1.5 as a novel pH‐dependent mechanism of action for tamoxifen

FEBS Open Bio, EarlyView.
Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr, Michael Fauler, Thomas Zimmer, Bettina Jungwirth, Hubert Schrezenmeier, David Alexander Christian Messerer   +5 more
wiley   +1 more source

HUBUNGAN FAKTOR MATERNAL DAN PERAWATAN BAYI DENGAN KEMATIAN NEONATAL PADA KELUARGA MISKIN DI KABUPATEN PADANG PARIAMAN TAHUN 2004 (RELATION OF MATERNAL FACTOR AND BABY NURSING WITH DEATH OF NEONATAL AT IMPECUNIOUS FAMILY OF YEAR 2004) [PDF]

, 2005
Kematian bayi merupakan indikator utama dalam pembangunan kesehatan. 50% Angka Kematian Bayi terdiri dari Angka Kematian Neonatal. Di Kabupaten Padang Pariaman Angka Kematian Bayi sebesar 1,9%, 87,9% dari kematian bayi berasal dari neonatal, dan 75,2 ...
YANDRIDA, ROSLIDAR
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Characterization of porcine endogenous retrovirus expression in neonatal and adult pig pancreatic islets [PDF]

, 2017
BACKGROUND: Pig islets represent an alternative to the current modes of treatment for patients with diabetes. However, the concerns over pathogen transmission including that of PERV limit their immediate, widespread usage in humans.
Akiyoshi, Bittmann, Claire Crossan, Clemenceau, Clemenceau, Cooper, Denner, Denner, Denner, Dieckhoff, Fishman, Gazda, Guo, Irgang, Kimsa, Korbutt, Linda Scobie, Matsumoto, Mazurek, Moon, Morozov, Mourad, Mueller, Nizar I. Mourad, Patience, Pierre Gianello, Pizzato, Schuurman, Scobie, Spizzo, Sypniewski, Tacke, Tucker, Victoria Cruikshank, Wynyard, Wynyard, Zhang   +36 more
core   +1 more source

BCS1L‐Associated Disease: 5′‐UTR Variant Shifts the Phenotype Towards Axonal Neuropathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To investigate the consequences of a pathogenic missense variant (c.838C>T; p.L280F) and a 5′‐UTR regulatory variant (c.‐122G>T) in BCS1L on disease pathogenesis and to understand how regulatory variants influence disease severity and clinical presentation.
Rotem Orbach, Nunziata Maio, Russell J. Butterfield, A. Reghan Foley, Sarah Silverstein, Yan Li, Katherine Chao, Tanya J. Lehky, Abigail Potticary, Tracey A. Rouault, Sandra Donkervoort, Carsten G. Bönnemann   +11 more
wiley   +1 more source

Expertise and the interpretation of computerized physiological data: implications for the design of computerized monitoring in neonatal intensive care [PDF]

, 2001
This paper presents the outcomes from a cognitive engineering project addressing the design problems of computerized monitoring in neonatal intensive care.
ALBERDI, ALBERDI, ALBERDI, ANDY LYON, AZEVEDO, BARNARD, BOSHUIZEN, CARD, CARROLL, CHASE, CHI, CLAESSEN, COIERA, COIERA, COIERA, CUNNINGHAM, CUNNINGHAM, DEERE, EDWORTHY, EGAN, ELSTEIN, ELSTEIN, ERICSSON, ERICSSON, ERICSSON, ERICSSON, EUGENIO ALBERDI, FELTOVICH, FELTOVICH, GILHOOLY, GILHOOLY, GRAY, GREEN, GREEN, GREMY, HAIMOWITZ, JAN REISS, JIM HUNTER, JOSEPH, JULIE-CLARE BECHER, KEN GILHOOLY, LANDAUER, LARKIN, LARKIN, LEMIEUX, LESGOLD, LESGOLD, LOGIE, LONG, LONG, MCINTOSH, MORGAN, NEIL MCINTOSH, NENOV, NORMAN, PATEL, PATEL, PATEL, PATEL, PATEL, ROBERT LOGIE, SALATIAN, SCHMIDT, SCHMIDT, TABOADA, WICKENS   +65 more
core   +1 more source

Neurobehavior of term neonates with neonatal hyperbilirubinemia

Journal of Pediatric Neurosciences, 2013
To find the effect of neonatal hyperbilirubinemia on neurobehavior of term infants.This study was undertaken in the neonatal unit of our tertiary care hospital. Term neonates who developed jaundice with serum bilirubin value of above 15 mg/dl within 1(st) week of life were enrolled in the study.
Noyal Mariya Joseph, Thirunavukkarasu Arun Babu, B Vishnu Bhat   +2 more
openaire   +4 more sources