Neurobehavioral consequences of chronic intrauterine opioid exposure in infants and preschool children: a systematic review and meta-analysis [PDF]
<b>Background</b><p></p> It is assumed within the accumulated literature that children born of pregnant opioid dependent mothers have impaired neurobehavioral function as a consequence of chronic intrauterine opioid use.<p>&
A Baldacchino +86 more
core +12 more sources
Neonatal abstinence syndrome: Diagnostic dilemmas in the maternity ward [PDF]
Introduction. Neonatal abstinence syndrome (NAS) refers to a newborn neurological, gastrointestinal and/or respiratory disorder if a newborn was exposed to psychoactive substances in the intrauterine period.
Lazić-Mitrović Tanja +6 more
doaj +1 more source
Neonatal abstinence syndrome: a never ending story!
Neonatal Abstinence syndrome (NAS) is the result of fetal exposure to illicit or prescription drugs (for example opioids, benzodiazepines, and selective serotonin reuptake inhibitors) taken by the mother prenatally.
Johannes N. van den Anker
doaj +1 more source
BackgroundNeonatal abstinence syndrome (NAS) is common, expensive, and hurts opioid addicted women and their families. Current treatments do not sufficiently address comorbid addictions, especially tobacco use, among pregnant buprenorphine-maintained ...
Sarah Tabi +8 more
doaj +1 more source
Maternal methadone use in pregnancy : factors associated with the development of neonatal abstinence syndrome and implications for healthcare resources [PDF]
The objectives of this study were to investigate factors associated with the development of neonatal abstinence syndrome (NAS) and to assess the implications for healthcare resources of infants born to drug-misusing women. Design.
Dryden, C. +3 more
core +1 more source
Vibrotactile stimulation: A non-pharmacological intervention for opioid-exposed newborns. [PDF]
To examine the therapeutic potential of stochastic vibrotactile stimulation (SVS) as a complementary non-pharmacological intervention for withdrawal in opioid-exposed newborns.A prospective, within-subjects single-center study was conducted in 26 opioid ...
Ian Zuzarte +5 more
doaj +1 more source
This case report highlights the difficulties in diagnosing non-ketotic hyperglycinemia in a neonate with maternal substance abuse and neonatal abstinence syndrome.
Hirad Houjaghani, Reza Behmadi
doaj +1 more source
Neonatal outcomes following in utero exposure to buprenorphine/naloxone or methadone
Objectives: To study neonatal outcomes following buprenorphine/naloxone and methadone exposure during pregnancy. Methods: This study is a retrospective review of clinical and demographic information of 58 infants whose mothers were treated with ...
Kristen M Gawronski +5 more
doaj +1 more source
Neonatal abstinence syndrome is a potential cause of low TREC copy number
Severe combined immunodeficiency (SCID) is a rare genetic condition characterized by significant T cell lymphopenia and impaired T cell function. Many jurisdictions use the quantitation of T cell receptor excision circles (TRECs) to screen for SCID in ...
Adil Adatia +4 more
doaj +1 more source
Process Improvement for Maximized Therapeutic Innovation Outcome. [PDF]
Deconvoluting key biological mechanisms forms the framework for therapeutic discovery. Strategies that enable effective translation of those insights along the development and regulatory path ultimately drive validated clinical application in patients ...
Terzic, Andre, Waldman, Scott A.
core +2 more sources

