Results 41 to 50 of about 650,274 (148)

Uncovering the Genetic Landscape of Spinal Dysraphism: A Retrospective Analysis of 150 Fetal Cases

Prenatal Diagnosis, Volume 46, Issue 5-6, Page 849-861, May 2026.
ABSTRACT Objective Spinal dysraphism (SD) results from incomplete neural tube closure and encompasses a heterogeneous group of congenital anomalies with genetic and environmental etiologies. Although genetic contributions are recognized, causative variants remain insufficiently defined, and the clinical implications of extended genetic testing on ...
I. Bedei, A. Feresin, R. Zemet, D. Berner, D. Polidori, K. Fröbius, A. Skakkebæk, R. Axt‐Fliedner, M. Shoukier, C. Keil   +9 more
wiley   +1 more source

Topical Minoxidil and Low‐Dose Oral Minoxidil in Onychodystrophy: A Proposed Treatment Algorithm

Journal of Cosmetic Dermatology, Volume 25, Issue 4, April 2026.
ABSTRACT Background Onychodystrophy includes diverse nail disorders that may impair function and quality of life. Because nails grow slowly, adjunctive therapies that promote nail growth are of increasing interest. Aim This review examines the evidence for minoxidil in nail growth and nail disorders and proposes a treatment algorithm for its adjunctive
Aditya K. Gupta, Mesbah Talukder, Shari R. Lipner   +2 more
wiley   +1 more source

Maternal and Pediatric Precision in Therapeutic Knowledge Portal (MPRINT‐KP): Landscape Analysis of Pharmacology Research in Maternal and Pediatric Patient Populations

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 46, Issue 3, March 2026.
ABSTRACT Pregnant women and children have been underrepresented in clinical studies due to ethical concerns and perceived vulnerabilities. This resulted in a significant gap in knowledge regarding the safety and efficacy of medications for these populations.
Xiaofu Liu, Aditi Shendre, Lei Wang, Aislinn O'Kane, Hanson Ma, Chien‐Wei Chiang, Syed S. Zaidi, Omar A. Aboshady, Gerald So, Emma M. Tillman, Lindsey M. Kirkpatrick, Maged Costantine, Shaun Grannis, Colin M. Rogerson, Christopher Bartlett, Saurabh Rahurkar, Lijun Cheng, Jiayi Ouyang, Ping Wei, Zhimo Zhu, Shangjia Li, Yirui Huang, Lingling Wang, Weidan Cao, Haoran Jiang, Jianing Liu, Samuel‐Richard Oteng, Andrew Goodwin, Jiezel Ann Faith Deypalubos, Shijun Zhang, Robert Bies, Sara K. Quinney, Lang Li   +32 more
wiley   +1 more source

Herpès Néonatal à Localisation Périnéale : À Propos de Deux Cas Illustrant les Défis du Diagnostic Précoce au Gabon

Health Research in Africa
RÉSUMÉ L’herpès néonatal est une urgence pédiatrique rare mais dévastatrice, dont le pronostic dépend de la précocité du traitement. Sa présentation est souvent atypique, retardant la prise en charge.
Koumba Maniaga R, Minto’o Rogombe S, Lembet Mikolo MA, Nzila Matoumba GM, Mboungani M, Dibungg D’Yfungg GA, Kuissi Kamgaing E, Ategbo S   +7 more
doaj   +1 more source

Heat Stress Modulates WDR5‐Mediated H3K4me3 Modification to Induce Melanogenesis via Activating CX3CL1/CX3CR1 Axis

Advanced Science, Volume 13, Issue 7, 3 February 2026.
This study elucidates the mechanism by which heat stress regulates skin pigmentation: heat stress upregulates CX3CL1 through the MYC‐WDR5‐H3K4me3 axis, thereby activating the CX3CL1/CX3CR1‐JNK signaling pathway and ultimately promoting melanogenesis. These findings provide novel potential therapeutic targets for pigmentary skin disorders.
Yushan Zhang, Ling Jiang, Yibo Hu, Chuhan Fu, Jinhua Huang, Jing Chen, Qinghai Zeng   +6 more
wiley   +1 more source

Recognizing Presentations of Pemphigoid Gestationis: A Case Study

Case Reports in Obstetrics and Gynecology, 2014
Introduction. Pemphigoid gestationis (PG) is an autoimmune blistering disease that occurs in approximately 1 in 50,000 pregnancies. Failing to recognize PG may lead to inadequate maternal treatment and possible neonatal complications. Case Report.
Sadie Henry
doaj   +1 more source

Molecular Identification and Evaluation of Resistance to Antifungal Drugs in Candida Species Isolated From Diaper Rash of Neonates

Health Science Reports, Volume 9, Issue 2, February 2026.
ABSTRACT Background Diaper dermatitis, also recognized as diaper rash, is one of the most frequent skin conditions in neonates. Materials and Methods A total of 100 babies participated in the study. Eligibility included neonates aged 5–28 days and full‐time diaper wearers.
Fariba Shirvani, Mahsa Fattahi, Abdollah Karimi, Shahnaz Armin, Seyed Alireza Fahimzad, Sedigheh Rafiei Tabatabaei, Roxana Mansour Ghanaei, Fatemeh Fallah, Alireza Firooz, Shahrzad Tabatabaee, Mitra Radfar, Dorsa Kalani, Hossein Foroozan, Afagh firoozgaeean Galoogah, Pegah Tamimi   +14 more
wiley   +1 more source

Spesolimab for treatment of generalized pustular psoriasis of pregnancy

Pregnancy, Volume 2, Issue 1, January 2026.
Abstract Introduction Generalized pustular psoriasis (GPP) is a severe, desquamating skin disorder associated with pregnancy that presents as fever, fatigue, malaise and sterile pustules. It is associated with profound maternal morbidity, maternal mortality, placental insufficiency and stillbirth.
Jason Bunn, Christine Henricks, Aaminah Azhar, Cristina Thomas, Edward Hadeler, Alexandra Smith, R. Nicholas Burns, Jarad Levin, Marvin Williams, Hugh Nadeau   +9 more
wiley   +1 more source

Acometimento neonatal do pênfigo vulgar: relato de caso

, 2020
Os penfigos sao dermatoses bolhosas autoimunes, em que ha a producao de autoanticorpos direcionados contra moleculas de adesao dos epitelios, levando a perda da coesao celular.
Mariana das Neves Melo, E. Pegas
semanticscholar   +1 more source

Mapping VEXAS‐associated and rare UBA1 variants in the United Kingdom: Insights from patient cohorts and the general population

British Journal of Haematology, Volume 208, Issue 1, Page 116-128, January 2026.
VEXAS syndrome is a late‐onset inflammatory disorder with rheumatological and haematological features. Epidemiological studies of VEXAS syndrome so far have been limited. Analysis of various UK cohorts estimates the incidence of VEXAS to be 1.51/100 000, or 171 new cases in the population of men over the age of 50 who are being investigated for myeloid
Ana Martinez Rodriguez, Leon Chang, Dorota Rowczenio, Alexandra Smith, Ebun Omoyinmi, James A. Poulter, Andrew McGregor, Sebastian Francis, Roochi Trikha, Adam Al‐Hakim, Kar Lok Kong, David G. Kent, Helen Lachmann, Austin Kulasekararaj, Catherine Cargo, Sinisa Savic   +15 more
wiley   +1 more source