Results 21 to 30 of about 57,085 (307)

Early changes in brain structure correlate with language outcomes in children with neonatal encephalopathy. [PDF]

, 2017
Global patterns of brain injury correlate with motor, cognitive, and language outcomes in survivors of neonatal encephalopathy (NE). However, it is still unclear whether local changes in brain structure predict specific deficits.
Barkovich, A James, Ferriero, Donna M, Gano, Dawn, Glass, Hannah C, Gorno-Tempini, Maria Luisa, Kim, Hosung, Mandelli, Maria Luisa, Rogers, Elizabeth E, Shapiro, Kevin A, Xu, Duan   +9 more
core   +2 more sources

Bi-allelic GAD1 variants cause a neonatal onset syndromic developmental and epileptic encephalopathy. [PDF]

, 2020
Developmental and epileptic encephalopathies are a heterogeneous group of early-onset epilepsy syndromes dramatically impairing neurodevelopment. Modern genomic technologies have revealed a number of monogenic origins and opened the door to therapeutic ...
Alix, E, Alkaya, DU, Ashrafzadeh, F, Becker, F, Bilguvar, K, Chatron, N, de Bellescize, J, EuroEpinomics-RES consortium AR working group, Gunes, N, Hardies, K, Hussien, H, Karimiani, EG, Kok, F, Labalme, A, Lerche, H, Lesca, G, Maroofian, R, May, P, Morsy, H, Moslemi, A-R, Nabil, A, Najafi, M, Omar, T, Poulat, A-L, Ramos, L, Roselli, S, Sanlaville, D, Schmidts, M, Tajsharghi, H, Tuysuz, B, Weckhuysen, S   +30 more
core   +2 more sources

Electrographic Seizures in Neonates with a High Risk of Encephalopathy

Children, 2022
Background: Neonatal encephalopathy is caused by a wide variety of acute brain insults in newborns and presents with a spectrum of neurologic dysfunction, such as consciousness disturbance, seizures, and coma.
Wan-Hsuan Chen, Oi-Wa Chan, Jainn-Jim Lin, Ming-Chou Chiang, Shao-Hsuan Hsia, Huei-Shyong Wang, En-Pei Lee, Yi-Shan Wang, Cheng-Yen Kuo, Kuang-Lin Lin, on the behalf of the iCNS Group   +10 more
doaj   +1 more source

Moderate hypothermia within 6 h of birth plus inhaled xenon versus moderate hypothermia alone after birth asphyxia (TOBY-Xe): a proof-of-concept, open-label, randomised controlled trial [PDF]

, 2015
Background Moderate cooling after birth asphyxia is associated with substantial reductions in death and disability, but additional therapies might provide further benefit.
Azzopardi, D, Bainbridge, A, Cady, E, Charles-Edwards, G, Deierl, A, Edwards, AD, Fagiolo, G, Franks, NP, Griffiths, J, Hajnal, J, Juszczak, E, Kapetanakis, B, Linsell, L, Maze, M, Omar, O, Robertson, NJ, Strohm, B, Tusor, N   +17 more
core   +2 more sources

Hypothermia and Neonatal Encephalopathy [PDF]

Pediatrics, 2014
This Clinical Report was reaffirmed September 2021. Data from large randomized clinical trials indicate that therapeutic hypothermia, using either selective head cooling or systemic cooling, is an effective therapy for neonatal encephalopathy. Infants selected for cooling must meet the criteria outlined in published clinical trials.
Lu-Ann, Papile, Jill E, Baley, William, Benitz, James, Cummings, Waldemar A, Carlo, Eric, Eichenwald, Praveen, Kumar, Richard A, Polin, Rosemarie C, Tan, Kasper S, Wang   +9 more
openaire   +2 more sources

High blood pressure, a red flag for the neonatal manifestation of urea cycle disorders

Orphanet Journal of Rare Diseases, 2019
Background Neonatal manifestation of life-threatening hyperammonemic encephalopathy in urea cycle disorders (UCD) is often misdiagnosed as neonatal sepsis, resulting in significantly delayed start of specific treatment and poor outcome.
Ulrike Teufel, Peter Burgard, Jochen Meyburg, Martin Lindner, Johannes Poeschl, Peter Ruef, Georg F. Hoffmann, Stefan Kölker   +7 more
doaj   +1 more source

Effect of intra-partum Oxytocin on neonatal encephalopathy: a systematic review and meta-analysis

BMC Pregnancy and Childbirth, 2021
Background Oxytocin is widely used for induction and augmentation of labour, particularly in low- and middle-income countries (LMICs). In this systematic review and meta-analysis, we examined the effect of intra-partum Oxytocin use on neonatal ...
Constance Burgod, Stuti Pant, Maria Moreno Morales, Paolo Montaldo, Phoebe Ivain, Ramyia Elangovan, Paul Bassett, Sudhin Thayyil   +7 more
doaj   +1 more source

Serum Hsp70 antigen: Early diagnosis marker in perinatal asphyxia [PDF]

, 2015
BACKGROUND: Perinatal asphyxia is an important cause of mortality and permanent neurological and developmental deficit. Early and accurate diagnosis would help to establish the likely prognosis and may also help in determining the most appropriate ...
Boskabadi, Hassan, Ferns, Gordon A A, Mobarhan, Majid Ghayour, Mohammadi, Shabnam, Omidian, Masoud, Parizadeh, Mostafa, Tavallai, Shima   +6 more
core   +1 more source

THE MAIN HEMOSTATIC PROFILES OF NEWBORN INFANT WITH NEONATAL ENCEPHALOPATHY IN WINTER PERIOD

Паёми Сино, 2017
Objective: To establish the character and intensity of the disorders of the coagulability and fibrinolytic systems at the full-term newborn infants with neonatal encephalopathy in the winter period.
M.N. KHOTAMOVA, J.S. DODKHOEV, G.S. MAMADZHANOVA, KH.J. AMINOV   +3 more
doaj   +1 more source

Severe hepatopathy and neurological deterioration after start of valproate treatment in a 6-year-old child with mitochondrial tryptophanyl-tRNA synthetase deficiency [PDF]

, 2018
Background: The first subjects with deficiency of mitochondrial tryptophanyl-tRNA synthetase (WARS2) were reported in 2017. Their clinical characteristics can be subdivided into three phenotypes (neonatal phenotype, severe infantile onset phenotype ...
De Bruyne, Ruth, Menten, Björn, Roels, Frank, Roeyers, Herbert, Smet, Joél, Stepman, Hedwig, Van Coster, Rudy, Vanlander, Arnaud, Vantroys, Elise, Vergult, Sarah   +9 more
core   +1 more source