Results 1 to 10 of about 57,085 (307)

Hypothermia for encephalopathy in low and middle-income countries (HELIX): study protocol for a randomised controlled trial [PDF]

Trials, 2017
Background Therapeutic hypothermia reduces death and disability after moderate or severe neonatal encephalopathy in high-income countries and is used as standard therapy in these settings.
Sudhin Thayyil, Vania Oliveira, Peter J. Lally, Ravi Swamy, Paul Bassett, Mani Chandrasekaran, Jayashree Mondkar, Sundaram Mangalabharathi, Naveen Benkappa, Arasar Seeralar, Mohammod Shahidullah, Paolo Montaldo, Jethro Herberg, Swati Manerkar, Kumutha Kumaraswami, Chinnathambi Kamalaratnam, Vinayagam Prakash, Rema Chandramohan, Prathik Bandya, Mohammod Abdul Mannan, Ranmali Rodrigo, Mohandas Nair, Siddarth Ramji, Seetha Shankaran, for the HELIX Trial group   +24 more
doaj   +3 more sources

A bibliometric study on clinical research in neonatal encephalopathy [PDF]

Frontiers in Pediatrics
This research presents a comprehensive review of studies on neonatal encephalopathy conducted between 2005 and 2024, utilizing knowledge graph analysis through CiteSpace and VOSviewer software.
Shujun Tan, Shujun Tan, Shujun Tan, Shujun Tan, Gulizuohere Alimujiang, Gulizuohere Alimujiang, Gulizuohere Alimujiang, Gulizuohere Alimujiang, Nuerya Rejiafu, Nuerya Rejiafu, Nuerya Rejiafu   +10 more
doaj   +2 more sources

Neonatal Encephalopathy due to Glutaminase Deficiency in a Neonate [PDF]

Clinical Case Reports
Identifying neurometabolic disorders that lead to neonatal encephalopathy is difficult, and access to exome sequencing is a significant advantage in developing countries.
Unnati Achanta, Shrinidhi Krishnan, Ashok Chandrasekaran, Robert Wilson S, Senthil Kumar Aiyappan, Subash Sundar   +5 more
doaj   +2 more sources

Neonatal encephalopathy: a systematic review of reported treatment outcomes [PDF]

BMJ Paediatrics Open
Background Neonatal encephalopathy (NE) is a multi-organ condition potentially leading to death or long-term neurodisability. Therapeutic hypothermia is the standard treatment for NE; however, long-term impairments remain common.
James Webbe, Karen Walker, Mandy Daly, Eleanor Molloy, Malcolm Battin, Jamie J Kirkham, Tim Hurley, Declan Devane, Linda Biesty, Patricia Healy, Shireen Meher, Fiona Quirke, David M Haas, Elaine Ní Bhraonáin, Frank Harry Bloomfield, Elaine Finucane   +15 more
doaj   +2 more sources

Risk factors of mortality in neonates with neonatal encephalopathy in a tertiary newborn care unit in Zimbabwe over a 12-month period.

PLOS Global Public Health, 2022
Neonatal encephalopathy (NE) accounts for ~23% of the 2.4 million annual global neonatal deaths. Approximately 99% of global neonatal deaths occur in low-resource settings, however, accurate data from these low-resource settings are scarce.
Hannah Gannon, Gwendoline Chimhini, Mario Cortina-Borja, Tarisai Chiyaka, Marcia Mangiza, Felicity Fitzgerald, Michelle Heys, Samuel R Neal, Simbarashe Chimhuya   +8 more
doaj   +2 more sources

Multi-Round versus Real-Time Delphi survey approach for achieving consensus in the COHESION core outcome set: a randomised trial

Trials, 2023
Background Delphi surveys are commonly used to prioritise critical outcomes in core outcome set (COS) development. This trial aims to compare a three-round (Multi-Round) Delphi (MRD) with a Real-Time Delphi (RTD) in the prioritisation of outcomes for ...
Fiona A. Quirke, Malcolm R. Battin, Caitlin Bernard, Linda Biesty, Frank H. Bloomfield, Mandy Daly, Elaine Finucane, David M. Haas, Patricia Healy, Tim Hurley, Sarah Koskei, Shireen Meher, Eleanor J. Molloy, Maira Niaz, Elaine Ní Bhraonáin, Christabell Omukagah Okaronon, Farhana Tabassum, Karen Walker, James R. H. Webbe, Matthew J. Parkes, Jamie J. Kirkham, Declan Devane   +21 more
doaj   +1 more source

Core outcomes in neonatal encephalopathy: a qualitative study with parents

BMJ Paediatrics Open, 2022
Objective To identify the outcomes considered important to parents or caregivers of infants diagnosed with neonatal encephalopathy, hypoxic ischaemic encephalopathy or birth asphyxia in high-income and low- to middle-income countries (LMiCs), as part of ...
Karen Walker, Mandy Daly, Eleanor Molloy, Malcolm Battin, Jamie J Kirkham, Shabina Ariff, Tim Hurley, Frank H Bloomfield, Declan Devane, Linda Biesty, Patricia Healy, Shireen Meher, Fiona Quirke, Caitlin Bernard, David M Haas, Vincent Kibet, Sarah Koskei, Maira Niaz, Elaine Ní Bhraonáin, Christabell Omukagah Okaronon, Farhana Tabassum   +20 more
doaj   +1 more source

KCNQ2 Encephalopathy Showing a Distinct Ictal Amplitude-Integrated Electroencephalographic Pattern [PDF]

Neonatal Medicine, 2020
KCNQ2 mutations induce a neonatal-onset epileptic encephalopathy of widely varying severity, ranging from benign familial neonatal epilepsy to severe refractory epileptic encephalopathy.
Naeun Kwak, Yun Jeong Lee, Dongsub Kim, Su-Kyeong Hwang, Soonhak Kwon, Eun Joo Lee   +5 more
doaj   +1 more source

COHESION: core outcomes in neonatal encephalopathy (protocol)

Trials, 2021
Background Neonatal encephalopathy is a complex syndrome in infants that predominantly affects the brain and other organs. The leading cause is a lack of oxygen in the blood reaching the brain.
Fiona A. Quirke, Patricia Healy, Elaine Ní Bhraonáin, Mandy Daly, Linda Biesty, Tim Hurley, Karen Walker, Shireen Meher, David M. Haas, Frank H. Bloomfield, Jamie J. Kirkham, Eleanor J. Molloy, Declan Devane   +12 more
doaj   +1 more source

Mimicking Hypoxic-Ischemic Encephalopathy in a Newborn with 21q Deletion Originating from Ring Chromosome 21

Children, 2023
Partial deletion of the long arm (q) in chromosome 21 is an extremely rare condition with various phenotypes, including microcephaly, neurodevelopmental delay, dysmorphic features, and epileptic seizures. Neonatal hypoxic-ischemic encephalopathy (HIE) is
Ja Un Moon, Sook Kyung Yum
doaj   +1 more source