Results 221 to 230 of about 55,479 (259)

Reducing neonatal Fc receptor binding enhances clearance and brain-to-blood ratio of TfR-delivered bispecific amyloid-β antibody. [PDF]

MAbs
Schlein E, Andersson KG, Dallas T, Syvänen S, Sehlin D.   +4 more
europepmc   +1 more source

Association of the neonatal Fc receptor promoter variable number of tandem repeat polymorphism with immunoglobulin response in patients with chronic inflammatory demyelinating polyneuropathy. [PDF]

Eur J Neurol
Fisse AL, Schäfer E, Hieke A, Schröder M, Klimas R, Brünger J, Huckemann S, Grüter T, Sgodzai M, Schneider-Gold C, Gold R, Nguyen HP, Pitarokoili K, Motte J, Arning L.   +14 more
europepmc   +1 more source

Endocytotic Albumin Uptake Pathways in Human Adipose Stem Cells and Connection to Intracellular Calcium Oscillations and the Neonatal Fc receptor.

Cells Tissues Organs
Morshed MT, Bernhardt A, Wartenberg M, Sauer H.   +3 more
europepmc   +1 more source

The neonatal Fc receptor: Key to homeostasic control of IgG and IgG-related biopharmaceuticals. [PDF]

Am J Transplant, 2019
Baldwin WM, Valujskikh A, Fairchild RL.
europepmc   +1 more source

Neonatal Fc receptor antagonist, efgartigimod, for chronic ITP

Japanese Journal of Thrombosis and Hemostasis
openaire   +1 more source

Some of the next articles are maybe not open access.

Related searches:

FcRn: the neonatal Fc receptor comes of age

Nature Reviews Immunology, 2007
The neonatal Fc receptor for IgG (FcRn) has been well characterized in the transfer of passive humoral immunity from a mother to her fetus. In addition, throughout life, FcRn protects IgG from degradation, thereby explaining the long half-life of this class of antibody in the serum. In recent years, it has become clear that FcRn is expressed in various
Roopenian, D C, Akilesh, S
openaire   +4 more sources

Neonatal Fc Receptor Inhibitor Therapeutics in Neuromuscular Disease

Journal of Clinical Neuromuscular Disease, 2023
Abstract The Neonatal Fc Receptor (FcRn) is integral to a wide variety of processes including IgG recycling, serum albumin turnover, and bacterial opsonization. Thus, targeting FcRn will increase antibody degradation including pathogenic IgGs.
Mustafa Jaffry, Daniel L. Menkes, Anam Shaikh, Kranthi Mandava, Om Kothari, Kazim Jaffry, Nizar Souayah   +6 more
openaire   +2 more sources

Regulation of dendritic cell function by Fc-γ-receptors and the neonatal Fc receptor

Molecular Immunology, 2021
Dendritic cells (DCs) express receptors to sense pathogens and/or tissue damage and to communicate with other immune cells. Among those receptors, Fc receptors (FcRs) are triggered by the Fc region of antibodies produced during adaptive immunity. In this review, the role of FcγR and neonatal Fc receptor (FcRn) in DC immunity will be discussed.
Christophe, Macri, Huw, Morgan, Jose A, Villadangos, Justine D, Mintern   +3 more
openaire   +2 more sources

Targeting neonatal Fc receptor: potential clinical applications in pregnancy

Ultrasound in Obstetrics & Gynecology, 2022
ABSTRACTThe neonatal Fc receptor (FcRn) plays an important role in the transfer of the immunoglobulin G isotype (IgG) from the mother to the fetus. FcRn expressed on endothelial cells also binds to IgG and albumin, regulating the circulating half‐lives of these proteins. Alloimmune and autoimmune IgG antibodies have been implicated in various perinatal
K. J. Moise, D. Oepkes, E. Lopriore, R. G. M. Bredius   +3 more
openaire   +3 more sources