Results 111 to 120 of about 88,069 (217)

Clinically Suspected Acute Post-Measles Encephalitis Complicated by Paracetamol-Induced Hepatotoxicity in an Unvaccinated Child: A Case Report from a Resource-Limited Setting

Infection and Drug Resistance
Widad Mohamed Hassan,1 Fartun Abdullahi Hassan Orey,2 Mohamed Saleh Saleh,3 Zubier Abdulkadir Mohamed,4 Rayaan Abdirahman Hassan,1 Abdullahi Hassan Elmi5 1Dr. Sumait Hospitals, Faculty of Medicine and Health Sciences, SIMAD University, Mogadishu, Somalia;
Hassan WM, Orey FAH, Saleh MS, Mohamed ZA, Hassan RA, Elmi AH   +5 more
doaj  

Human Infection with Japanese Encephalitis Virus Genotype V, China, 2025. [PDF]

Emerg Infect Dis
Zou W, Peng Y, Li J, Cai L, Tang W, Yang J, Li X, Xu J, Liang G.   +8 more
europepmc   +1 more source

Astrocyte‐Associated ABCA1/APOE Responses Accompany Hippocampal Lipid Remodeling and Ectopic Neuronal Accumulation During Epileptogenesis

Advanced Science, EarlyView.
During kainic acid‐induced epileptogenesis, astrocyte‐associated ATP‐binding cassette transporter A1 (ABCA1) and apolipoprotein E (APOE) responses accompany ectopic neurons and exploratory lipid alterations. In separate cohorts, bexarotene pretreatment and treatment on days 14–21 are associated with fewer ectopic hilar neurons and lower chronic seizure
Lu Chen, Xiao‐Rui Shi, Jia‐Yi Chen, Ying‐Ting Wang, Le Du, Yang Ni, Jun‐Min Chen, An‐Chen Guo, Qian Wu, Jian‐Ping Wu, Qun Wang   +10 more
wiley   +1 more source

Comparative metabolomics of paired maternal-cord samples identifies pathway-level divergence. [PDF]

Metabolomics
Van Winckel A, Gupta M, Klein R, Puvvula J, Braun JM, Pennell KD, DeFranco EA, Ho SM, Leung YK, Vuong AM, Percy Z, Bhashyam P, Lee R, Jones DP, Tran V, Kim DV, Huang S, Chen A, Manz KE.   +18 more
europepmc   +1 more source

Astrocytic Ketogenesis Protects Central Nervous System Injury via CPT1A Stabilization and Epigenetic Regulation

Advanced Science, EarlyView.
A distinct astrocyte subpopulation, enriched at the lesion border, drives CNS repair through enhanced ketone body metabolism. This process promotes neuronal survival and axonal sparing via CPT1A stabilization and H3K9bhb‐dependent epigenetic reprogramming, positioning astrocytic ketogenesis as a promising therapeutic target for tissue regeneration ...
Dishui Pan, Haoming Shu, Rui Gao, Yilong Ren, Wu Ye, Xuhui Ge, Yao Gu, Yufeng Zhu, Xiaokun Wang, Honglin Teng, Xuhui Zhou, Wei Liu, Yang Gao, Jianquan Zhao, Weihua Cai   +14 more
wiley   +1 more source

A Rare Constellation of Omphalocele, Myelomeningocele, and Encephalocele in a Neonate Born to a Mother With Type 2 Diabetes Mellitus: A Case Report. [PDF]

Clin Case Rep
Amin JHJ, Shakeel N, Mohammed ASK, Mohammed R, Omer AMB, Mahgoob AM.   +5 more
europepmc   +1 more source

Macrophage GLUD1 is Essential for Redox Balance and Immune Homeostasis in Cardiac Injury

Advanced Science, EarlyView.
Excessive free radical production and dysregulated immune responses are key contributors to myocardial ischemia‐reperfusion (IR) injury. Macrophage GLUD1 activity safeguards against HIF‐1α accumulation and maladaptive responses to IR‐induced ROS production.
Tingting Jin, Chaojie Lai, Qingyan Zhou, Ruilin Wang, Yiping Tong, Wentao Chen, Nikola Rabrenovic, Tingyu Zhang, Xinrong Ren, Chengchen Huang, Jiawen Chen, Ran Li, Luyang Yu, Massimiliano Mazzone, Wenbin Zhang, Guosheng Fu, Min Shang   +16 more
wiley   +1 more source

What the Dying are Saying to the Living: Mixed Conspecific Alarm Cues Reverse Competitive Hierarchies by Reshaping Genotype-Specific Life Histories. [PDF]

Ecol Evol
Tian X, Zhang Q, Li C, Feng W, Zhang X.
europepmc   +1 more source

Arhgef1 Deletion Disrupts Early Cortical Neurogenesis via PAK1 Overactivation and Causes Motor Dysfunction in Adulthood

Advanced Science, EarlyView.
ARHGEF1 plays a pivotal role in both embryonic cortical neurogenesis and adult motor function. During early development, it governs genesis of deep‐layer cortical neurons by negatively regulating RAC1/CDC42‐PAK1‐Cofilin signaling. In adulthood, ARHGEF1 is important for the maintenance of neuronal morphology and activity in the motor cortex, ensuring ...
Liuren Li, Xuanyue Ma, Zhenyu Ding, Bang Sun, Linglin Liu, Hei Matthew Yip, Wei Wang, Tianying Wu, Yuan Guo, Yinghui Peng, Shiqing Zhang, Jacque Pak Kan Ip, Li Zhang, Keshen Li, Lei Shi   +14 more
wiley   +1 more source

Lenticulostriate vasculopathy in neonates: An imaging marker with heterogeneous clinical significance. [PDF]

Radiol Case Rep
El Azouzi M, Belkouchi L, El Haddad S, Allali N, Chat L.   +4 more
europepmc   +1 more source