Do Harbour Porpoise Mortality Records Reflect Living Population Structure? A Matrix Population Model Diagnostic. [PDF]
Ecol EvolSøgaard MKSMH, Wahlberg M, Jones OR.
europepmc +1 more source
Advanced Science, EarlyView.CKMT1 inhibits VDAC1 oligomerization via a dual‐region mechanism: its NTD interacts with the VDAC1 C‐terminal domain, while residues 1–39 sterically hinder dimerization, thereby reducing mtDNA leakage and AIM2 inflammasome activation, suppressing neuronal pyroptosis and protecting against cerebral ischemic injury. ABSTRACT Ischemic stroke is one of the
Xiaoyu Wang +17 more
wiley +1 more source
Late-Onset Sepsis and Meningitis Caused by <i>Elizabethkingia meningoseptica</i>: A Case Report. [PDF]
Infect Drug ResistLiao S, Qiu S, Li N, Liu Y, Tang X.
europepmc +1 more source
Applied Economic Perspectives and Policy, EarlyView.ABSTRACT Using nationwide data on the US Environmental Protection Agency's Risk Management Plan (RMP) program, we examine the proportions of underserved populations living near facilities that use extremely hazardous chemicals, both before and after accidents involving fires, explosions, and/or toxic vapors occur.
Karlee Cook +3 more
wiley +1 more source
Voriconazole and Dexamethasone Drug Interaction in a Premature Neonate. [PDF]
J Pediatr Pharmacol TherLiviskie CJ +4 more
europepmc +1 more source
Concurrent Germline RB1 & Mosaic TP53 in a Child With Multiple Childhood Cancers
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT We report a patient with a pathogenic germline variant (PGV) in RB1 and somatic mosaicism for a pathogenic TP53 variant who developed three distinct types of childhood cancer: retinoblastoma, osteosarcoma, and myelodysplastic syndrome (MDS) before the age of 6 years.
Ole Haubjerg Nielsen +8 more
wiley +1 more source
A Rare Case Report of Nosocomial Urosepsis due to <i>Klebsiella pneumoniae</i> in a Preterm Neonate Complicated by Acute Cystitis. [PDF]
Case Rep Infect DisSim B, Kok S, Im S, Bin S.
europepmc +1 more source
COX14 Variants Are Associated With Mitochondrial Complex IV Deficiency Nuclear Type 10 (MC4DN10)
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT COX14 encodes a transmembrane protein essential for cytochrome c oxidase (COX) complex assembly. A homozygous missense variant in COX14 was reported in three siblings from a single consanguineous family with severe, fatal infantile mitochondrial complex IV deficiency nuclear type 10 (MC4DN10; MIM# 619053).
Elias K. Awad +7 more
wiley +1 more source
Risk-adapted first-stage patent ductus arteriosus ligation for an anomalous left brachiocephalic trunk arising from the main pulmonary artery in a critically ill neonate: a case report and literature review. [PDF]
Int J Surg Case RepPeerapatanapong K, Samankatiwat P.
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Heterozygous Variants in LRP1 Cause a Neurodevelopmental Disorder With Congenital Heart Defects
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT LRP1 encodes the low‐density lipoprotein (LDL) receptor‐related protein 1 (LRP1), a transmembrane protein involved in endocytosis and activation of multiple signaling pathways. LRP1 variants have been implicated in the pathogenesis of congenital heart defects (CHD), Alzheimer's disease, and neurodevelopmental disorders (NDD).
Alyssa L. Rippert +31 more
wiley +1 more source