Results 141 to 150 of about 115,482 (301)

Comparative metabolomics of paired maternal-cord samples identifies pathway-level divergence. [PDF]

Metabolomics
Van Winckel A, Gupta M, Klein R, Puvvula J, Braun JM, Pennell KD, DeFranco EA, Ho SM, Leung YK, Vuong AM, Percy Z, Bhashyam P, Lee R, Jones DP, Tran V, Kim DV, Huang S, Chen A, Manz KE.   +18 more
europepmc   +1 more source

Dual‐Gene Edited Extracellular Vesicles Remodel the Redox Homeostasis to Inhibit Ferroptosis in Intervertebral Disc Degeneration

Advanced Science, EarlyView.
ABSTRACT Intervertebral disc degeneration (IDD) is driven by ferroptosis of nucleus pulposus cells (NPCs) as a core pathological mechanism. Nucleus pulposus progenitor cells (NPPCs), exhibiting stem cell‐like properties, yield extracellular vesicles (PEVs) with high affinity for NPCs and enable targeted phenotypic regulation.
Jing Yan, Yazhou Lin, Shuo Miao, Minghao Chao, Chengbai Dai, Ziwen Hao, Rui Chen, Ming Guan, Bin Pan, Fenglei Gao, Quan Zhou   +10 more
wiley   +1 more source

Clinically Suspected Acute Post-Measles Encephalitis Complicated by Paracetamol-Induced Hepatotoxicity in an Unvaccinated Child: A Case Report from a Resource-Limited Setting

Infection and Drug Resistance
Widad Mohamed Hassan,1 Fartun Abdullahi Hassan Orey,2 Mohamed Saleh Saleh,3 Zubier Abdulkadir Mohamed,4 Rayaan Abdirahman Hassan,1 Abdullahi Hassan Elmi5 1Dr. Sumait Hospitals, Faculty of Medicine and Health Sciences, SIMAD University, Mogadishu, Somalia;
Hassan WM, Orey FAH, Saleh MS, Mohamed ZA, Hassan RA, Elmi AH   +5 more
doaj  

Alobar Holoprosencephaly with Severe Craniofacial Anomalies and Congenital Diaphragmatic Hernia: First Reported Case from Somalia. [PDF]

Pediatric Health Med Ther
Osman IM, Mohamed AM, Abdi KS, Mohamed NM.   +3 more
europepmc   +1 more source

Care of the neonate with neonatal abstinence syndrome

, 2018
Neonatal abstinence syndrome is defined as a condition where neonates have experienced in utero exposure to opioids or other substances used by the mother causing withdrawal symptoms 24-72 hours post birth (Edwards & Brown, 2016).
Flint, Andrea, Needham, Judith
core  

Intrasplenic Thymus Organogenesis from Injectable Tissue Fragments Restores Functional T‐Cell Immunity

Advanced Science, EarlyView.
Clinical intramuscular thymus transplantation yields only short‐lived efficacy and marginal therapeutic benefits. Benefiting from the spleen's intrinsic strengths—rapid vascular perfusion, abundant developmental factors, and resident progenitors—the intrasplenic thymic grafts achieve robust thymic regeneration and substantial T‐cell reconstitution ...
Shaocong Wang, Zijian Zhang, Fulin Dai, Zhijie Yin, Zhen Xing, Yurong Li, Haochong Lei, Junfeng Zhang, Chunyan Liu, Yan Li, Lei Dong   +10 more
wiley   +1 more source

Late Onset Gestational Diabetes Mellitus: Clinical Implications of Delayed Diagnosis and a Pragmatic Approach to Screening: A Narrative Review

Journal of Pregnancy
Ryosuke Shindo, Shigeru Aoki
doaj   +1 more source

What the Dying are Saying to the Living: Mixed Conspecific Alarm Cues Reverse Competitive Hierarchies by Reshaping Genotype-Specific Life Histories. [PDF]

Ecol Evol
Tian X, Zhang Q, Li C, Feng W, Zhang X.
europepmc   +1 more source

ZBTB18 Dysfunction Promotes Neuropathic Pain via CHD4‐based Epigenetic Disinhibition of CLIC1 Channels in Sensory Neurons

Advanced Science, EarlyView.
In this study, we identify a novel functional role of ZBTB18 in regulating trigeminal‐mediated neuropathic pain. Nerve injury reduces ZBTB18 in trigeminal ganglion neurons, impairing CHD4/NuRD recruitment and de‐repressing Clic1. Elevated CLIC1 enhances chloride channel activity and neuronal hyperexcitability, thereby driving pain.
Shoupeng Wang, Zitong Huang, Yu Tao, Yunmei Zhang, Yufang Sun, Dongsheng Jiang, Weiwei Lu, Fuhai Ji, Gang Chen, Min Xu, Yuan Zhang, Jin Tao   +11 more
wiley   +1 more source

Candidemia and invasive candidiasis in children and neonates: transposing adult diagnostic recommendations may undermine end-organ screening. [PDF]

Braz J Infect Dis
Pessoa FS.
europepmc   +1 more source