Results 121 to 130 of about 191,052 (217)

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Colorectal Cancer in Inflammatory Bowel Disease: How to Minimize the Risk. [PDF]

open access: yesCancers (Basel)
Nassera B   +8 more
europepmc   +1 more source

Lewy Body Disease Across Aging: Clinical and Neuropathological Correlates in a Population Brain Bank

open access: yesMovement Disorders, EarlyView.
Abstract Background Lewy body disease (LBD) is defined by neuronal α‐synuclein pathology, but how Braak‐staged LBD relates to mixed neuropathology and clinical manifestations within a single population‐based cohort remains incompletely characterized. This is especially relevant in cohorts enriched for younger individuals, which may better inform real ...
Vitor Ribeiro Paes   +13 more
wiley   +1 more source

TGF‐β Inhibition Attenuates Tau Accumulation and Neurodegeneration in Progressive Supranuclear Palsy Patient‐Derived Organoids

open access: yesMovement Disorders, EarlyView.
Abstract Background Progressive supranuclear palsy (PSP) is a devastating 4‐repeat tauopathy with no approved disease‐modifying treatments. Recent evidence showed increased transforming growth factor‐β (TGF‐β) levels in PSP patient‐derived ventral midbrain organoids (vMOs) and serum neuronally derived exosomes. Objective This study investigated whether
Mariagrazia Talarico   +8 more
wiley   +1 more source

AI‐Driven Rational Design of Nanotherapeutics for Pancreatic Ductal Adenocarcinoma

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) remains a formidable malignancy characterized by late diagnosis, high recurrence rates, and pronounced chemoresistance. While nanoparticle‐based drug delivery systems (NDDS) offer theoretical advantages over conventional therapies, their clinical translation in PDAC has been severely limited.
Seohyun Choo   +4 more
wiley   +1 more source

Primary Tumor Location and Lymphatic Spread in Papillary Thyroid Carcinoma

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Papillary thyroid carcinoma (PTC) frequently metastasizes to cervical lymph nodes. Surgical planning is often based on the presumed central‐to‐lateral pattern of spread. The extent of central and lateral neck dissection remains controversial, with recommendations largely derived from small series. The study aimed to determine whether
Isabelle Fournier   +23 more
wiley   +1 more source

Pink Polypoid Papulo‐Vesicles on Labia Majora

open access: yes
JEADV Clinical Practice, EarlyView.
Maria Chiara Mercuri   +3 more
wiley   +1 more source

Human Prostate Cell Lines: Derivation, Molecular Characteristics and Appropriate Use

open access: yesThe Prostate, EarlyView.
ABSTRACT Background Research on prostate cancer and benign prostatic hyperplasia depends on a small number of immortalized human cell lines established between 1977 and 2001, most of them from advanced metastatic disease. The cell lines differ from one another in androgen receptor status, prostate‐specific antigen secretion, p53 status, karyotype and ...
Hamza Abohamra, Keenau Mark Pearce
wiley   +1 more source

A 3D lymph node model for chronic lymphocytic leukaemia recapitulates microenvironmental features and drug response in vitro

open access: yesDisease Models & Mechanisms
Daniela Belloni   +12 more
doaj   +1 more source

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