Epithelioid Angiomyolipoma in a Patient With Li-Fraumeni Syndrome: Rare Pathologic Diagnosis
: Objective: Li-Fraumeni syndrome (LFS) is a rare familial cancer syndrome characterized by a high frequency of early onset tumors of various types, including adrenocortical carcinoma.
Sina Jasim, MD, MPH+6 more
doaj +1 more source
A novel therapeutic strategy for pancreatic neoplasia using a novel RNAi platform targeting PDX-1 [PDF]
Bi-functional shRNA (bi-shRNA), a novel RNA interference (RNAi) effector platform targeting PDX-1 utilizing a systemic DOTAP-Cholesterol delivery vehicle, was studied in three mouse models of progressive pancreatic neoplasia.
Charles Brunicardi+13 more
core +1 more source
The role of ras gene in the development of haemic neoplasia in Mytilus trossulus [PDF]
Disseminated neoplasia has been reported in mussels (Mytilus spp) from numerous locations worldwide. This condition is progressive and fatal and the aetiology is unknown.
Barber+9 more
core +2 more sources
Lactation and neonatal nutrition: defining and refining the critical questions. [PDF]
This paper resulted from a conference entitled "Lactation and Milk: Defining and refining the critical questions" held at the University of Colorado School of Medicine from January 18-20, 2012.
Ardythe L. Morrow+37 more
core +2 more sources
Early tumor response to intraarterial or intravenous administration of carboplatin to treat naturally occurring lower urinary tract carcinoma in dogs. [PDF]
BackgroundSurvival times and tumor responses associated with malignant neoplasia of the lower urinary tract are poor despite the vast array of current treatments.
Berent, AC+8 more
core
Immortalization of T-cells is accompanied by gradual changes in CpG methylation resulting in a profile resembling a subset of T-cell leukemias [PDF]
We have previously described gene expression changes during spontaneous immortalization of T-cells, thereby identifying cellular processes important for cell growth crisis escape and unlimited proliferation. Here, we analyze the same model to investigate
Borssén, Magnus+10 more
core +1 more source
When risk becomes illness: The personal and social consequences of cervical intraepithelial neoplasia medical surveillance [PDF]
[Abstract] Background, After the early detection of cervical intraepithelial neoplasia (CIN), medical surveillance of the precancerous lesions is carried out to control risk factors to avoid the development of cervical cancer. Objective.
Coronado, Carmen+3 more
core +1 more source
Muscular metastases (MMs) form an infrequent entity, and their physiopathology is still not well-defined. In this study, we estimated the incidence of MMs that were detected by 18F-fluorodeoxyglucose positron emission tomography/computed tomography and ...
Abderrahim Doudouh+2 more
doaj +1 more source
Mutations of the ret protooncogene in German multiple endocrine neoplasia families: Relation between genotype and phenotype. [PDF]
It has been suggested that not only the position but also the nature of the mutations of the ret protooncogene strongly correlate with the clinical manifestation of the multiple endocrine neoplasm type 2 (MEN 2) syndrome.
Deckart, H. F.+15 more
core +1 more source
Oncocytic Change in Thyroid Pathology
Oncocytes are cells that have abundant eosinophilic cytoplasm due to the accumulation of mitochondria; they are also known as oxyphils. In the thyroid they have been called Hürthle cells but this is a misnomer, since Hürthle described C cells; for this ...
Sylvia L. Asa+4 more
doaj +1 more source