Results 51 to 60 of about 585,185 (390)

The Argos project: The development of a computer-aided detection system to improve detection of Barrett's neoplasia on white light endoscopy

United European Gastroenterology journal, 2019
Background Computer-aided detection (CAD) systems might assist endoscopists in the recognition of Barrett's neoplasia. Aim To develop a CAD system using endoscopic images of Barrett's neoplasia.
J. de Groof, F. van der Sommen, J. A. van der Putten, M. Struyvenberg, S. Zinger, W. Curvers, O. Pech, A. Meining, H. Neuhaus, R. Bisschops, E. Schoon, P. D. De with, J. Bergman   +12 more
semanticscholar   +1 more source

European guidelines from the EHTG and ESCP for Lynch syndrome: an updated third edition of the Mallorca guidelines based on gene and gender

BJS (British Journal of Surgery), EarlyView., 2020
Recommendations for clinical and molecular identification of LS, surgical and endoscopic management of LS‐associated colorectal cancer and preventive measures for cancer were produced. The emphasis was on surgical and gastroenterological aspects of the cancer spectrum.
T. T. Seppälä, A. Latchford, I. Negoi, A. Sampaio Soares, R. Jimenez‐Rodriguez, L. Sánchez‐Guillén, D. G. Evans, N. Ryan, E. J. Crosbie, M. Dominguez‐Valentin, J. Burn, M. Kloor, M. von Knebel Doeberitz, F. J. B. van Duijnhoven, P. Quirke, J. R. Sampson, P. Møller, G. Möslein, on behalf of the European Hereditary Tumour Group (EHTG) and European Society of Coloproctology (ESCP)   +18 more
wiley   +1 more source

Mutations of the ret protooncogene in German multiple endocrine neoplasia families: Relation between genotype and phenotype. [PDF]

, 1996
It has been suggested that not only the position but also the nature of the mutations of the ret protooncogene strongly correlate with the clinical manifestation of the multiple endocrine neoplasm type 2 (MEN 2) syndrome.
Deckart, H. F., Dralle, H., Frank-Raue, K., Frilling, A., Haase, R., Hampel, R., Höppner, W., Kirchner, R., Klempa, J., Kotzerke, J., Mann, K., Raue, F., Rendl, J., Ritter, M. M., Scholz, G. H., Seif, F.   +15 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

A novel therapeutic strategy for pancreatic neoplasia using a novel RNAi platform targeting PDX-1 [PDF]

, 2011
Bi-functional shRNA (bi-shRNA), a novel RNA interference (RNAi) effector platform targeting PDX-1 utilizing a systemic DOTAP-Cholesterol delivery vehicle, was studied in three mouse models of progressive pancreatic neoplasia.
Charles Brunicardi, David Dawson, Donald Rao, Francesco DeMayo, John Nemunaitis, Kelly Stehling, Marie-Claude Gingras, Michael Norman, Nancy Templeton, Neil Senzer, Richard Gibbs, Shi-He Liu, William Fisher, Zhaohui Wang   +13 more
core   +1 more source

Contralateral prophylactic mastectomies. Correlations between primary tumor and histological findings of controlateral breast [PDF]

, 2016
Backgound: In Italy in 2015 48,000 new cases of breast carcinomas were diagnosed. Women who are diagnosed with breast cancer have a significant risk of developing contralateral breast cancer during the rest of their lives and this risk is closely ...
Amanti, Claudio, Argento, Giuseppe, Campanella, L, Cunsolo, G, DI STEFANO, Domenica, Lombardi, Augusto, Maggi, Stefano, Mastrangeli, Mr, Mattei, Ms, Stanzani, G, Vitale, Valeria   +10 more
core   +1 more source

FOXP3 Polymorphism and Upregulation of the CXCL12‐CXCR4‐SNAIL Axis with High Infiltration of M2TAM by STAT3/NFKB Pathways Influence the Survival of Cervical Cancer Patients

Advanced Biology, EarlyView.
This study highlights how cervical carcinoma progression is shaped by immune–tumor interactions within the TME. M2‐TAM infiltration, regulated through STAT3/NF‐κB and linked to CXCL12–CXCR4, promotes immune suppression, angiogenesis, and poor survival.
George A. Lira, Fábio M. de Azevedo, Ingrid G. S. Lins, Janaína C. O. Crispim, Giovanna A. Lira, Rômulo S. Cavalcante, Ricardo Cobucci, Carolina O. Mendes‐Aguiar, Rafaela Torres Dantas Da Silva, Vinícius E. da Silva, Ryan C. Q. Aquino, Raimundo F. Araújo Júnior   +11 more
wiley   +1 more source

Bioengineered Pancreatic Cancer Immunosuppressive Microenvironment Models for Screening Immunotherapies

Advanced Healthcare Materials, EarlyView.
Bioengineering tumor‐stroma pancreatic cancer models with potential to emulate the native immunosuppressive tumor microenvironment. Cancer‐on‐a‐bead models exhibited higher relevance for screening immunotherapies and modulating the protumoral PDAC microenvironment. ABSTRACT Pancreatic cancer is notably resistant to treatment, primarily due to its dense
Maria V. Monteiro, Margarida Henriques‐Pereira, Bruno M. Neves, Vítor M. Gaspar, João F. Mano   +4 more
wiley   +1 more source

Challenges in Cytology Specimens With Hürthle Cells

Frontiers in Endocrinology, 2021
In fine-needle aspirations (FNA) of thyroid, Hürthle cells can be found in a broad spectrum of lesions, ranging from non-neoplastic conditions to aggressive malignant tumors.
Eleni Thodou, Sule Canberk, Sule Canberk, Fernando Schmitt, Fernando Schmitt, Fernando Schmitt   +5 more
doaj   +1 more source

Forty-Year Analysis of Colonoscopic Surveillance Program for Neoplasia in Ulcerative Colitis: An Updated Overview [PDF]

, 2015
C.R.C. was funded by the Derek Willoughby Fund for Inflammatory Research. A.L.H. and T.A.G.
Ailsa L Hart, Alan Askari, Bernstein, Blackstone, Braakhuis, Brian P Saunders, Chang-Ho Ryan Choi, Connell, Connell, Eaden, Greenstein, Gui Han Lee, Hurlstone, Janindra Warusavitarne, Kiesslich, Marion, Matthew D Rutter, Morgan Moorghen, Nugent, Odze, Odze, Riddell, Rubin, Rutter, Rutter, Rutter, Siwan Thomas-Gibson, Trevor A Graham, van Schaik, van Schaik, Vieth, Wanders   +31 more
core   +1 more source