Results 21 to 30 of about 20,569 (202)

A multilevel perspective on MSH6‐associated Lynch syndrome: Integrating molecular, biological, and clinical insights

International Journal of Cancer, EarlyView.
Abstract Lynch syndrome (LS) is the most common hereditary colorectal cancer syndrome, caused by a germline pathogenic variant in one of the mismatch repair (MMR) genes. Among these, MSH6‐associated LS represents a distinct subtype with unique molecular and clinical characteristics.
Salwa Ben Yahia, Anne‐Sophie van der Werf‐'t Lam, Madalina Cabuta, Maartje Nielsen, Noah C. Helderman   +4 more
wiley   +1 more source

EPIDEMIOLOGIA DAS INTERNAÇÕES HOSPITALARES POR NEOPLASIA MALIGNA DE CÓLON NO BRASIL ENTRE 2009 E 2024

Revista de Epidemiologia e Saúde Pública
Objetivo: Investigar o perfil epidemiológico das internações hospitalares por neoplasia maligna de cólon no Brasil, no período de 2009 a 2024. Métodos: Estudo ecológico de perfil epidemiológico realizado no Brasil entre 2009 e 2024, com dados do SIH/SUS (
Jasmine Truppel Simas
doaj   +1 more source

Neoplasia Neuroendocrina - No Neuroendocrina de Colon (MINEN): Unificando Conceptos

Revista Argentina de Coloproctología
Las neoplasias neuroendócrinas representan un 1% de todas las neoplasias malignas del tubo digestivo, de las cuales, el 14-20% corresponden al colon y solo el 1 a 3% a neoplasias rectales. El 85% de las neoplasias colónicas son carcinomas neuroendocrinos pobremente diferenciados que contienen un componente no-neuroendocrino en el 25-40% de los casos ...
Rocio Soledad Perez Dominguez, Guillermina Candia, Rosario O. Martiarena, Sergio F. Schlain   +3 more
openaire   +1 more source

Artificial Intelligence in Colonoscopy Surveillance for Lynch Syndrome: Emerging Evidence, Lessons Learned From Average‐Risk Populations, and Future Directions

International Journal of Cancer, EarlyView.
ABSTRACT Lynch syndrome (LS) is the most common hereditary colorectal cancer (CRC) syndrome and is characterized by an accelerated adenoma‐carcinoma sequence, a relatively higher prevalence of flat and subtle CRC precursor lesions, and exceptionally high adenoma miss rates despite intensive colonoscopy surveillance.
Robert Hüneburg, Querijn N. E. van Bokhorst, Evelien Dekker, Jacob Nattermann   +3 more
wiley   +1 more source

Can the Parallel or Tandem Combination of Questionnaire‐Based Risk Assessment and Fecal Immunochemical Test Improve the Efficiency of Colorectal Cancer Screening?

International Journal of Cancer, EarlyView.
Colorectal cancer screening reduces disease burden, but the comparative performance of screening strategies remains unclear. This population‐based study shows that the tandem strategy (positive results from both questionnaire‐based risk assessment and fecal immunochemical testing) substantially improved the detection rates of colorectal cancer and ...
Ruyue Liu, Junyi Ji, Xiaolin Wei, Chao Zheng, Nan Zhang, Qiang Sun   +5 more
wiley   +1 more source

Colorectal Cancer Screening in Hereditary and Familial High‐Risk Populations: Best Practices and Future Directions

International Journal of Cancer, EarlyView.
ABSTRACT Colorectal cancer (CRC) remains a leading cause of cancer‐related morbidity and mortality worldwide yet is largely preventable through effective screening and surveillance. While most CRC cases are sporadic, a substantial proportion occur in individuals at increased risk due to hereditary cancer syndromes or family history who require tailored
Ophir Gilad, Francesc Balaguer, Elizabeth E. Half, Kevin J. Monahan, Elena M. Stoffel, Sonia S. Kupfer   +5 more
wiley   +1 more source

A case report of Peutz–Jeghers syndrome in a child with Crohn's disease

JPGN Reports, EarlyView.
Abstract Peutz–Jeghers syndrome (PJS) is a rare genetic disorder characterized by hamartomatous polyps and mucocutaneous hyperpigmented freckles, whereas Crohn's disease (CD) is a condition characterized by chronic intestinal inflammation. Here, we present a rare case report of an 11‐year‐old male who presented with both CD and PJS.
Hasala Rannulu, Eve May, Bethany Cunningham, Eric Cochran, Rachel Zdenek, Stefany H. Garrity   +5 more
wiley   +1 more source

Colonoscopia ou sigmoidoscopia: risco de lesões isoladas no cólon direito Colonoscopy or flexible sigmoidoscopy: risk of isolated right colon lesions

Arquivos de Gastroenterologia, 2001
Racional — Atualmente existem dúvidas quanto ao método ideal de rastreio e vigilância para o câncer colorretal. A retossigmoidoscopia é preconizada, já que é barata, eficaz e causa pouco desconforto, mas não pode diagnosticar tumores do cólon ...
Frank Shigueo NAKAO, Marcelo de Souza CURY, Angelo Paulo FERRARI Jr.   +2 more
doaj   +1 more source

A case report of non‐syndromic colonic ganglioneuroma in a patient with juvenile polyposis

JPGN Reports, EarlyView.
Abstract Colonic ganglioneuromas in children are rare, particularly without associated hereditary syndromes like multiple endocrine neoplasia (MEN2B), neurofibromatosis type 1(NF1), or Phosphatase and tensin homolog hamartoma tumor syndrome (PHTS). We report a 12‐year‐old male with a history of juvenile polyposis syndrome (JPS) and segmental colonic ...
Holly Coffey, Kshitij Arora, Matthew J. Giefer   +2 more
wiley   +1 more source

Aspectos clinicoepidemiológicos e histológicos en pacientes con cáncer de colon de la provincia de Guantánamo

Medisan, 2023
Introducción: El cáncer colorrectal es una de las neoplasias de mayor morbilidad y mortalidad a escala mundial. En Cuba ocupa la tercera causa de muerte por tumores malignos.
Raquel Onoria Cayon Poyeaux, Aurora Cayon Simonó, Yasnai Rivera Soto, Yamile Calzadilla Navarro, Erodis Hechavarría Matos   +4 more
doaj