Results 91 to 100 of about 199,596 (304)

UTILIDAD DEL PET-FDG EN PATOLOGÍA GINECO-ONCOLÓGICA

Revista Chilena de Obstetricia y Ginecología, 2007
El PET-FDG es un estudio de imágenes de cuerpo entero que evalúa el metabolismo glucídico celular. Su mayor utilidad es en oncología tanto en adultos como en niños.
Paulina Sierralta C, M. Josefina Jofré M, Teresa Massardo V, José Canessa G, Patricio González E, Robert Valdebenito B   +5 more
doaj  

Tumour Heterogeneity and Disease Infiltration as Paradigms of Glioblastoma Treatment Resistance

Onco
Isocitrate dehydrogenase wild-type glioblastoma, a Grade 4 malignant brain neoplasm, remains resistant to multimodal treatment, with a median survival of 16 months from diagnosis with no geographical bias.
Pulkit Malhotra, Ruman Rahman
doaj   +1 more source

A case of dysphagia

The Pan African Medical Journal, 2014
Esophageal strictures commonly complicate radiation therapy for neck and thoracic malignancies. We here report a case of radiation induced stricture esophagus and illustrate the classical barium esophagogram in this condition.
George Sarin Zacharia, Sandesh Kolassery
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

O papel da Citometria de Fluxo na avaliação da doença residual mínima em cães com Linfoma B difuso de células grandes [PDF]

, 2019
O linfoma representa um grupo heterógeno de neoplasias com origem na alteração maligna das células linfoides. Dependendo do tipo de células afetadas e do grau de desenvolvimento da doença, o linfoma pode apresentar diferentes comportamentos biológicos ...
Monteiro, Marta Filipa Pimenta Rainho
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Integration of Next-Generation Sequencing in Measurable Residual Disease Monitoring in Acute Myeloid Leukemia and Myelodysplastic Neoplasm

Cancers
Background/Objectives. Recent evidence underscores the prognostic and classificatory relevance of somatic mutations in myelodysplastic neoplasms (MDSs) and acute myeloid leukemia (AML). Methods. This prospective study assessed gene mutation dynamics via next-generation sequencing (NGS) in 84 MDS/AML patients treated with intensive chemotherapy or ...
Elena Crisà, Irene Dogliotti, Giuseppe Lia, Marco Cerrano, Ernesta Audisio, Giuseppe Lanzarone, Lucia Brunello, Daniela Caravelli, Fabrizio Carnevale Schianca, Enrico Berrino, Sara Erika Bellomo, Alice Bartolini, Ludovica Riera, Paola Francia di Celle, Gianluca Gaidano, Monia Lunghi, Luisa Giaccone, Benedetto Bruno   +17 more
openaire   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

The molecular pathogenesis of myeloproliferative neoplasms [PDF]

, 2010
Myeloproliferative neoplasms (MPNs) are a heterogeneous group of haematological stem cellmalignancies characterised by proliferation of one or more cells of the myeloid lineage.
Jones, Amy Victoria
core