Results 81 to 90 of about 851,717 (305)

Immunophenotypic patterns in precursor T-cell neoplasm

open access: yes, 2007
T-cell lymphoproliferative disorders are a heterogeneous group of lymphoid neoplasm that can mimic both benign conditions and non-hematopoietic tumors. In routine clinical practice, morphology and immunophenotyping forms the basis of their diagnosis.
Gupta, R.   +3 more
core   +2 more sources

The Effect of Histological Subtypes on Outcomes of Stage IV Epithelial Ovarian Cancer

open access: yesFrontiers in Oncology, 2018
Introduction: To examined survival outcome by histological subtypes in de novo stage IV epithelial ovarian cancer (EOC).Methods: Between 2004 and 2015, patients with stage IV EOC were included using the Surveillance, Epidemiology, and End Results program.
Juan Zhou   +6 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Preliminary Real-World Outcomes of Adjuvant Immunotherapy in Resected Esophageal Cancer: A Retrospective Study from Taiwan

open access: yesJournal of Chest Surgery
Background: The CheckMate 577 trial demonstrated that adjuvant nivolumab improves disease-free survival in patients with resected esophageal cancer following neoadjuvant chemoradiotherapy.
Chia Liu   +5 more
doaj   +1 more source

Tumour Heterogeneity and Disease Infiltration as Paradigms of Glioblastoma Treatment Resistance

open access: yesOnco
Isocitrate dehydrogenase wild-type glioblastoma, a Grade 4 malignant brain neoplasm, remains resistant to multimodal treatment, with a median survival of 16 months from diagnosis with no geographical bias.
Pulkit Malhotra, Ruman Rahman
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

UTILIDAD DEL PET-FDG EN PATOLOGÍA GINECO-ONCOLÓGICA

open access: yesRevista Chilena de Obstetricia y Ginecología, 2007
El PET-FDG es un estudio de imágenes de cuerpo entero que evalúa el metabolismo glucídico celular. Su mayor utilidad es en oncología tanto en adultos como en niños.
Paulina Sierralta C   +5 more
doaj  

A case of dysphagia

open access: yesThe Pan African Medical Journal, 2014
Esophageal strictures commonly complicate radiation therapy for neck and thoracic malignancies. We here report a case of radiation induced stricture esophagus and illustrate the classical barium esophagogram in this condition.
George Sarin Zacharia, Sandesh Kolassery
doaj   +1 more source

Peripheral giant cell granuloma

open access: yesContemporary Clinical Dentistry, 2012
Peripheral giant cell granuloma or the so-called "giant cell epulis" is the most common oral giant cell lesion. It normally presents as a soft tissue purplish-red nodule consisting of multinucleated giant cells in a background of mononuclear stromal ...
Padam Narayan Tandon   +4 more
doaj   +1 more source

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