The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Appendiceal Mucinous Neoplasms and Inflammatory Bowel Disease: Systematic Review of the Literature [PDF]
Alessandro Bonomi +4 more
openalex +1 more source
Explaining the Current Status of General Medicine Curriculum from the Perspective of Cancer Education Based on SWOT Analysis [PDF]
Introduction: Given the rapid advancements in the field of medicine, it is essential to review current status of curricula both quantitatively and qualitatively.
Dariush Muslimi +5 more
doaj
Acanthomatous Ameloblastoma: A Rare Entity
Ameloblastoma is a slow-growing and locally aggressive true neoplasm of enamel organ-type tissue which does not undergo differentiation to the point of enamel formation.
Kiran Vallamchetla +3 more
doaj +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Temporal trends of incidence of colorectal cancer in Isfahan, Iran, 2000–2011
Background: Case finding was improved to the population-based method at the Isfahan Cancer Registry (ICR) during 2005–2008. However, its effects on the number of registered colorectal cancer (CRC) cases and patients' age are not investigated.
Mehri Rejali +4 more
doaj +1 more source
Fine needle aspiration of thyroid nodules in a general teaching hospital setting performing moderate number of biopsies: Outcome of indeterminate cytologic results [PDF]
Introduction: Our aim was to assess the usefulness of fine-needle aspiration cytologic biopsy (FNA) of the thyroid in our general teaching hospital with average health care facility performing moderate number of such procedures and to evaluate the ...
Azarhoush, R. +2 more
core
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Neoplasm formation, a non-meristematic tissue growth on young field pea (Pisum sativum L.) pods is triggered in the absence of UV light and/or in response to oviposition by pea weevil (Bruchus pisorum L.).
Abel eTeshome +4 more
doaj +1 more source

