Results 21 to 30 of about 46,847 (244)

Diversity of Dynamics and Morphologies of Invasive Solid Tumors

, 2012
Complex tumor-host interactions can significantly affect the growth dynamics and morphologies of progressing neoplasms. The growth of a confined solid tumor induces mechanical pressure and deformation of the surrounding microenvironment, which in turn ...
Jiao, Yang, Torquato, Sal
core   +2 more sources

Multiparametric MRI of the bladder: inter-observer agreement and accuracy with the Vesical Imaging-Reporting and Data System (VI-RADS) at a single reference center [PDF]

, 2019
Objectives: To evaluate accuracy and inter-observer variability using Vesical Imaging-Reporting and Data System (VI-RADS) for discrimination between non-muscle invasive bladder cancer (NMIBC) and muscle-invasive bladder cancer (MIBC).
Barchetti, Giovanni, Buccilli, Dorelsa, Campa, Riccardo, Catalano, Carlo, Catto, James W. F., Ceravolo, Isabella, De Berardinis, Ettore, Del Giudice, Francesco, Gallucci, Michele, Panebianco, Valeria, Salvo, Vincenzo, Simone, Giuseppe   +11 more
core   +1 more source

Minimally invasive differential diagnosis of melanocytic intraocular neoplasms

Russian Ophthalmological Journal, 2023
Purpose: to analyze the mutation frequency of the GNAQ/GNA11 gene in circulating tumor DNA and genotypes of the polymorphic marker C3435T of the ABCB1 gene in a large sample of patients with intraocular melanocytic neoplasms (IMN).Material and methods.
A. Yu. Tsygankov, S. V. Saakyan, E. B. Myakoshina, A. M. Burdennyi, V. I. Loginov   +4 more
openaire   +2 more sources

A proteomic approach to identify endosomal cargoes controlling cancer invasiveness [PDF]

, 2017
We have previously shown that Rab17 - a small GTPase associated with epithelial polarity - is specifically suppressed by ERK2 signalling to promote an invasive phenotype.
Diaz-Vera, Jesica, Dornier, Emmanuel, Edwards, Joanne, Hernandez-Fernaud, Juan Ramon, MacPherson, Iain, Mitchell, Louise E., Norman, Jim C., Palmer, Sarah, Zanivan, Sara   +8 more
core   +2 more sources

Tissue engineered platforms for studying primary and metastatic neoplasm behavior in bone [PDF]

, 2021
Cancer is the second leading cause of death in the United States, claiming more than 560,000 lives each year. Osteosarcoma (OS) is the most common primary malignant tumor of bone in children and young adults, while bone is a common site of metastasis for
Griffin, Katherine H, Leach, J Kent, Randall, R Lor, Thai, Victoria L, Thorpe, Steven W   +4 more
core   +1 more source

Gelsolin induces colorectal tumor cell invasion via modulation of the urokinase-type plasminogen activator cascade [PDF]

, 2012
Gelsolin is a cytoskeletal protein which participates in actin filament dynamics and promotes cell motility and plasticity. Although initially regarded as a tumor suppressor, gelsolin expression in certain tumors correlates with poor prognosis and ...
Alan Prem Kumar, Antonio Moschetta, Benedict Yan, Celestial T. Yap, Ee Hong Tan, Hwee Kee Tay, Jingli Zhuo, Lalchhandami Tochhawng, Manikandan Jayapal, Manuel Salto-Tellez, Shing Chuan Hooi, Shiuan Koh, Sutherland K. Maciver, Yaw Chong Goh, Yaw Chyn Lim   +14 more
core   +6 more sources

Non-invasive treatment of epidermal keratinocyte neoplasms [PDF]

, 2018
The number of skin cancer and pre-cancer diagnoses is on the rise in the Netherlands. Approximately 1.4 million Dutch people aged 50 and older have actinic keratosis (AK), or pre-cancerous skin lesions. Photodynamic therapy (PDT) is a treatment method that uses a special medicinal cream and a special lamp. Our research found that laser therapy leads to
openaire   +2 more sources

Pituitary Neoplasm Nomenclature Workshop: Does Adenoma Stand the Test of Time? [PDF]

, 2021
The WHO Classification of Endocrine Tumours designates pituitary neoplasms as adenomas. A proposed nomenclature change to pituitary neuroendocrine tumors (PitNETs) has been met with concern by some stakeholder groups.
Barkan, Ariel, Ben-Shlomo, Anat, Bidlingmaier, Martin, Biermasz, Nienke R., Boguszewski, Margaret, Bollerslev, Jens, Brue, Thierry, Buchfelder, Michael, Camper, Sally, Casanueva, Felipe, Casar-Borota, Olivera, Chanson, Philippe, Fleseriu, Maria, Fowkes, Robert C, Fukuoka, Hidenori, Gadelha, Monica, Greenman, Yona, Grossman, Ashley, Gurnell, Mark, Heaney, Anthony, Ho, Ken, Hoffman, Andrew R, Johannsson, Gudmundur, Kaiser, Ursula, Karavitaki, Niki, Katznelson, Laurence, Korbonits, Marta, Kunz, Pamela, Laws, Edward, Lopes, M. Beatriz, Mamelak, Adam, Melmed, Shlomo, Molitch, Mark, Nishioka, Hiroshi, Osamura, Robert, Oyesiku, Nelson, Pereira, Alberto, Radovick, Sally, Reincke, Martin, Roncaroli , Federico, Rverot, Gerald, Salvatori, Roberto, Shimon, Ilan, Syro, Luis V., Trainer, Peter J, Van Der Lely, A.J., Villa, Chiara, Wass, John, Zatelli, Maria Chiara   +48 more
core   +6 more sources

Prognosis of invasive intraductal papillary mucinous neoplasms of the pancreas

World Journal of Gastrointestinal Surgery, 2010
Intraductal papillary mucinous neoplasms (IPMN) are mucin producing cystic neoplasms of the pancreas histologically classified as having non-invasive and invasive components. The five-year survival rates for non-invasive and associated invasive carcinoma are 90% and 40%, respectively in resected IPMN lesions.
Peter J. Allen, Adam C. Yopp
openaire   +3 more sources

Identification of novel small molecule inhibitors of ETS transcription factors

FEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla, Zary Forghany, Jin Ma, Johan G. Hollander, Ruta Nachane, Karoly Szuhai, Pancras C. W. Hogendoorn, Peter ten Dijke, Dipen Shah, David A. Baker   +9 more
wiley   +1 more source