Results 31 to 40 of about 46,847 (244)

Determination of Malignant and Invasive Predictors in Branch Duct Type Intraductal Papillary Mucinous Neoplasms of the Pancreas: A Suggested Scoring Formula [PDF]

, 2011
Prediction of malignancy or invasiveness of branch duct type intraductal papillary mucinous neoplasm (Br-IPMN) is difficult, and proper treatment strategy has not been well established. The authors investigated the characteristics of Br-IPMN and explored
Baik Hwan Cho, Bernard, Chang-Sup Lim, Chiu, Chul Kyoon Cho, Dae Wook Hwang, Dong Wook Choi, Dong-Shik Lee, Hee Chul Yu, Ho-Seong Han, Hong-Jin Kim, Hwang, Hyun Jong Kim, In-Sang Song, Jang, Jang, Jin Seok Heo, Jin-Young Jang, Kawamoto, Koo Jung Kang, Kubo, Kuroki, Kyung Yul Hur, Longnecker, Moons, Mun Sup Sim, Ohashi, Okabayashi, Paik, Sahani, Salvia, Salvia, Sang Geol Kim, Sang-Jae Park, Schmidt, Seong Ho Choi, Seong-Sik Han, Serikawa, Seung Eun Lee, Sohn, Sugiyama, Sun-Whe Kim, Sung-Su Yun, Tae Jin Lim, Tanaka, Waters, Wiesenauer, Yamao, Yoo-Seok Yoon, Young Joon Ahn, Young Kook Yun   +50 more
core   +2 more sources

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

Inhibitive effect of triptolide on invasiveness of human fibrosarcoma cells by downregulating matrix metalloproteinase—9 expression [PDF]

, 2011
ObjectiveTo explore the molecular mechanisms of antitumor properties of triptolide, a bioactive component isolated from the Chinese herb Tripterygium wolfordii Hook F.MethodsHuman fibrosarcoma HT-1080 cells were treated with different doses of triptolide
Gu, Can, Huang, Jinhua, Kang, Jian, Lu, Qianjin, Wen, Haiquan, Yang, Shengbo, Zhang, Guiying   +6 more
core   +1 more source

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

FEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

Genetic structure of community acquired methicillin-resistant Staphylococcus aureus USA300. [PDF]

, 2012
BackgroundCommunity-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) is a significant bacterial pathogen that poses considerable clinical and public health challenges.
Bansal, Vikas, Bradley, John S, Cannavino, Christopher R, Leake, John AD, Schork, Nicholas J, Tewhey, Ryan, Topol, Eric J, Torkamani, Ali   +7 more
core   +2 more sources

Autophagy in cancer and protein conformational disorders

FEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Evolutionary interplay between viruses and R‐loops

FEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi, Zita Képes, Zoltán Szabó, Eszter Csoma, Lóránt Székvölgyi   +4 more
wiley   +1 more source

Alterations of FHIT and P53 genes in keratocystic odontogenic tumor, dentigerous and radicular cyst [PDF]

, 2008
BACKGROUND: The purpose of this study was to determine fragile histidine triad (FHIT) and p53 protein expression, and to analyze FHIT and p53 gene status in keratocystic odontogenic tumor (KOT), dentigerous cysts (DC) and radicular cysts (RC ...
Anić, Ivica, Jukić, Silvana, Kapitanović, Sanja, Krušlin, Božo, Malčić, Ana, Pavelić, Božidar, Pavelić, Krešimir   +6 more
core   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

Molecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever, Renske D. M. Steenbergen   +1 more
wiley   +1 more source

Feline vestibular disorders. Part II: diagnostic approach and differential diagnosis. [PDF]

, 1999
Results of a neurological examination usually permit localisation of a vestibular disorder to either the central or peripheral parts of the vestibular system. Many different disorders located in the same part of the vestibular system will produce similar
LeCouteur, RA, Vernau, KM
core