Results 51 to 60 of about 1,816,312 (333)
Oncogene, 2011 Epithelial–mesenchymal transition (EMT) is a crucial mechanism for the acquisition of migratory and invasive capabilities by epithelial cancer cells. By conducting quantitative proteomics in experimental models of human prostate cancer (PCa) metastasis ...
Shumin M. Zhang +17 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Pathological and Clinical Significance of Tumor Budding and Its Association with Epithelial-Mesenchymal Transition in Colorectal Carcinoma: A Retrospective Observational Study [PDF]
Iranian Journal of Medical SciencesBackground: Metastases, not the primary tumor, account for most cancer-related deaths. Tumor budding, thought to represent epithelial-mesenchymal transition (EMT), has garnered attention due to its association with invasion and migration. This study aims
Bashar Al Hassawi
doaj +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Extensively Invasive Gallbladder Cancer from Intracholecystic Papillary Neoplasm Treated with Pylorus-Preserving Pancreaticoduodenectomy and Extended Cholecystectomy: A Case Report and Literature Review [PDF]
, 2023 Hideki Kumagai +7 more
openalex +1 more source
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
INVASIVE CARCINOMA DERIVED FROM INTRADUCTAL PAPILLARY NEOPLASM
Pancreas, 2007 膵管内乳頭粘液性腫瘍（intraductal papillary-mucinous neoplasms：IPMNs）は，1982年大橋らが主膵管内の多量の粘液貯留に起因する主膵管拡張と十二指腸乳頭口開大などの臨床的特徴を示す予後の良い膵癌として「粘液産生膵癌」と命名し報告して以来，四半世紀の25年が経過した．四半世紀過ぎたことにより"IPMNs由来の浸潤癌"も多く報告がなされており，これらの報告をもとに特徴をまとめると以下のようになる．平均年齢は65歳前後，性差は男性に多い．好発部位は頭部で，60%以上同部がしめる．浸潤部の組織型はほとんど（90%以上）が粘液癌と管状腺癌である．両者の比率はほぼ同様であり，通常の浸潤性膵管癌組織型における粘液癌のしめる頻度から考えると粘液癌の比率が非常に高い ...
openaire +2 more sources
Journal of Korean medical science, 2011 Prediction of malignancy or invasiveness of branch duct type intraductal papillary mucinous neoplasm (Br-IPMN) is difficult, and proper treatment strategy has not been well established. The authors investigated the characteristics of Br-IPMN and explored
D. Hwang +26 more
semanticscholar +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
European Journal of Radiology OpenPurpose: The aim of this study was to explore and develop a preoperative and noninvasive model for predicting spread through air spaces (STAS) status in lung adenocarcinoma (LUAD) with diameter ≤ 3 cm.
Yangfan Su +7 more
doaj +1 more source