Results 161 to 170 of about 510,515 (305)

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Predictive performance of image processing techniques in the diagnosis of bone metastasis: A meta-analysis of a confusion matrix. [PDF]

Oncol Lett
Hu Y, Liao W, Er Y, Tao Q.
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Cervical metastasis from occult neoplasm

, 1970
In about 8% of cases presenting with metastatic disease in cervical lymph nodes, there is initial failure to find the primary lesion. Correct management of such a case consists in searching for a primary lesion in the head and neck and, if unsuccessful, elsewhere.
openaire   +1 more source

Multidisciplinary care in the management of pleomorphic dermal sarcoma: A single-center case series and review. [PDF]

JAAD Case Rep
Mehta J, Wardeh L, Suriano J, Dasgupta R, Hafer R, Elder A, Bhatti S, Lee JB, Mallick AB, Nikbakht N.   +9 more
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Solitary Parotid Metastasis as an Atypical Site of Recurrence in Lung Squamous Cell Carcinoma: A Diagnostic Difficulty. [PDF]

Cureus
Prateaux MA, Haouane MA, Rharrassi I, Azami MA.   +3 more
europepmc   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Scalp and Neck Metastasis From HER2-Positive Gastric Cancer: A Case Report and Literature Review. [PDF]

Case Rep Oncol Med
Fernández-Ferreira R, Montaño-Hernández J, Cantú-Pedraza RG, Delgado-Gutierrez F, Flores-Vazquez RA, Durán-Aceves ML, Bautista-Piña V, Vicuña-González RM, Burguete-Bojalil MD, De-Lucio-Chavero GI.   +9 more
europepmc   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source