Results 11 to 20 of about 494,128 (290)

Estrogen-regulated proteins cathepsin D and pS2 in breast carcinoma [PDF]

open access: yesArchive of Oncology, 2006
In addition to classical prognostic/predictive factors, significant biological markers have been identified to provide potentially relevant information regarding natural or clinical course of breast cancer.
Markićević Milan   +3 more
doaj   +1 more source

Correlation of local and systemic expression of survivin with histopathological parameters of cutaneous melanoma [PDF]

open access: yesVojnosanitetski Pregled, 2016
Background/Aim. Survivin is a multifunctional protein abundantly expressed in tumors of various types, including melanoma. There are still sparse data regarding relationship of melanoma cell survivin expression with accepted histopathological ...
Jović Milena   +9 more
doaj   +1 more source

EPLIN, Epithelial protein lost in neoplasm [PDF]

open access: yesOncogene, 1999
We have identified a novel cytoskeletal protein, EPLIN (Epithelial Protein Lost In Neoplasm), that is preferentially expressed in human epithelial cells. Two EPLIN isoforms, a 600 amino acid EPLIN-alpha and a 759 amino acid EPLIN-beta, are detected in primary epithelial cells of oral mucosa, prostate and mammary glands. The expression of EPLIN-alpha is
R S, Maul, D D, Chang
openaire   +2 more sources

Increased levels of a subset of angiogenesis-related plasma proteins in essential thrombocythemia

open access: yesUpsala Journal of Medical Sciences, 2023
Background: Increased local angiogenesis is important for the growth and dissemination of cancer. The myeloproliferative neoplasm essential thrombocythemia (ET) is known to involve increased bone marrow angiogenesis.
Sofia Vikman   +3 more
doaj   +1 more source

Deficient Mismatch Repair Proteins in Gastric Mixed Neuroendocrine Non-Neuroendocrine Neoplasm: A Rare Case Report

open access: yesCase Reports in Oncology, 2023
Mixed neuroendocrine non-neuroendocrine neoplasm (MiNEN) is a rare type of gastric carcinoma with controversial diagnosis and treatment. Recent data implies that deficiency mismatch repair proteins inducing microsatellite instability are considered one ...
Thi Hong Chuyen Nguyen   +7 more
doaj   +1 more source

FOP is a centriolar satellite protein involved in ciliogenesis. [PDF]

open access: yesPLoS ONE, 2013
Centriolar satellites are proteinaceous granules that are often clustered around the centrosome. Although centriolar satellites have been implicated in protein trafficking in relation to the centrosome and cilium, the details of their function and ...
Joanna Y Lee, Tim Stearns
doaj   +1 more source

NDRG1 protein overexpression in malignant thyroid neoplasms [PDF]

open access: yesClinics, 2010
The aim of this study was to examine the expression of the N-myc downstream-regulated gene 1 protein in benign and malignant lesions of the thyroid gland by immunohistochemistry.N-myc downstream-regulated gene 1 encodes a protein whose expression is induced by various stimuli, including cell differentiation, exposure to heavy metals, hypoxia, and DNA ...
Gerhard, Renê   +4 more
openaire   +5 more sources

Proteolysis-targeting chimeras and their implications in breast cancer

open access: yesExploration of Targeted Anti-tumor Therapy, 2021
Breast cancer (BC) is a highly heterogeneous neoplasm of the mammary tissue, causing the deaths of a large number of women worldwide. Nearly 70% and 20% of BC cases are estrogen receptor alpha positive (ERα+) and human epidermal growth factor receptor 2 ...
Angeles C. Tecalco-Cruz   +3 more
doaj   +1 more source

Nonimmune fluorescent protein staining of neoplasms [PDF]

open access: yesExperimental and Molecular Pathology, 1963
Abstract The nonimmunospecific tissue binding of protein-fluorochrome conjugates has been investigated. Such binding was specific in attachment to benign tissue, excluding malignant tissue, when fluorescein or rhodamine isocyanate was use according to the method of Hughes and Louis (1959) .
Miller, Edmund Kenneth   +3 more
openaire   +2 more sources

The Correlation between Proliferative Immunohistochemical Markers and Papillary Thyroid Carcinoma Aggressiveness

open access: yesMedicina, 2023
Background and Objectives: Papillary thyroid carcinoma (PTC) is one of the most common malignancies of the endocrine system. In order to improve the ability to predict tumor behavior, several studies have been conducted to search for surrogate prognostic
Mohammad Sheikh-Ahmad   +10 more
doaj   +1 more source

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