Results 31 to 40 of about 525,558 (314)

Using Neural Networks for Relation Extraction from Biomedical Literature

, 2020
Using different sources of information to support automated extracting of relations between biomedical concepts contributes to the development of our understanding of biological systems.
A Koike, A Lamurias, A Lamurias, A Lamurias, A Lamurias, A Singhal, AV Aho, B Xu, CD Manning, CH Alves, D Westergaard, D Zhou, E Guresen, F Rinaldi, HC Wang, HM Müller, J Hastings, L Aroyo, M Ashburner, MY Kim, N Ma, N Peng, P Goyal, P Zweigenbaum, PN Robinson, Q Li, QL Nguyen, S HayKin, S Hochreiter, TR Gruber, W Wang, WWM Fleuren, Y Hao, Y Luo, Y Xu   +34 more
core   +1 more source

Pre-B-cell acute lymphoblastic leukemia with bulk extramedullary disease and chromosome 22 (EWSR1) rearrangement masquerading as Ewing sarcoma [PDF]

, 2010
We report a 2-year-old female with a subcutaneous tumor who was initially misdiagnosed as suffering from Ewing sarcoma with a positive EWSR1 rearrangement and EWS/FLI1 transcript.
Jakovljević, Gordana, Kardum-Skelin, Ika, Krušlin, Božo, Mrsić-Davidović, Sanja, Nakić, Melita, Rogošić, Srđan, Zadro, Renata   +6 more
core   +1 more source

Myeloid transformation of plasma cell myeloma: molecular evidence of clonal evolution revealed by next generation sequencing

Diagnostic Pathology, 2018
Background Plasma cell myeloma (PCM) is a neoplasm of terminally differentiated B lymphocytes with molecular heterogeneity. Although therapy-related myeloid neoplasms are common in plasma cell myeloma patients after chemotherapy, transdifferentiation of ...
Jonathon H. Gralewski, Ginell R. Post, Frits van Rhee, Youzhong Yuan   +3 more
doaj   +1 more source

Molecular markers of recurrence of basal cell skin cancer [PDF]

Vestnik Dermatologii i Venerologii, 2023
Basal cell carcinoma is the most common malignant neoplasm, andits incidence has been rapidly increasing worldwide. This malignancy is a serious public health problem that can lead to disability and severe aesthetic damage. The results of the analysis
Rifat R. Saytburkhanov, Alexey A. Kubanov, Irina N. Kondrakhina, Xenia I. Plakhova   +3 more
doaj   +1 more source

Downregulating Notch counteracts KrasG12D-induced ERK activation and oxidative phosphorylation in myeloproliferative neoplasm. [PDF]

, 2019
The Notch signaling pathway contributes to the pathogenesis of a wide spectrum of human cancers, including hematopoietic malignancies. Its functions are highly dependent on the specific cellular context. Gain-of-function NOTCH1 mutations are prevalent in
Chang, Yuan-I, Hofmann, Inga, Kong, Guangyao, Letson, Christopher, Liu, Yangang, Loh, Mignon, Padron, Eric, Pear, Warren S, Qian, Shuiming, Rajagopalan, Adhithi, Ranheim, Erik A, Stieglitz, Elliot, Wen, Zhi, Yang, David, You, Xiaona, Zhang, Jing, Zhang, Jingfang, Zhang, Xinmin, Zhong, Xuehua, Zhou, Lan, Zhou, Yun   +20 more
core   +1 more source

Role of hypoxia-related proteins in adenoid cystic carcinoma invasion

Diagnostic Pathology, 2020
Background Among cancers affecting the oral cavity, adenoid cystic carcinoma (ACC) is a relatively common malignant neoplasm. It has high rates of metastasis and recurrence and is associated with significant morbidity.
Raíssa Pinheiro de Mendonça, Giordanna Pereira Chemelo, Geovanni Pereira Mitre, Dimitra Castelo Branco, Natacha Malu Miranda da Costa, Fabrício Mesquita Tuji, Maria Sueli da Silva Kataoka, Ricardo Alves Mesquita, Sérgio de Melo Alves Júnior, João de Jesus Viana Pinheiro   +9 more
doaj   +1 more source

A case of hepatic small vessel neoplasm without previously reported hotspot mutation of alpha subfamily of G proteins

Human Pathology Reports, 2022
Hepatic small vessel neoplasm (HSVN) is a very rare and recently described entity. Moreover, it is a vascular neoplasm of the liver composed of small vessels with infiltrative borders that mimic hepatic angiosarcoma.
Minako Yamamura, Yasunori Sato, Kenta Takahashi, Hiep Nguyen Canh, Zihan Li, Kazuyoshi Hosomichi, Atsushi Tajima, Takuro Terada, Yasuni Nakanuma, Kenichi Harada   +9 more
doaj   +1 more source

The SMAC mimetic LCL-161 selectively targets JAK2V617F mutant cells. [PDF]

, 2020
Background:Evasion from programmed cell death is a hallmark of cancer and can be achieved in cancer cells by overexpression of inhibitor of apoptosis proteins (IAPs).
Craver, Brianna M, Fleischman, Angela G, Huynh, Christy, Morse, Sarah J, Nguyen, Hellen, Nguyen, Jenny, Nguyen, Thanh Kim   +6 more
core  

Repurposing drugs to target nonalcoholic steatohepatitis [PDF]

, 2019
Nonalcoholic fatty liver disease (NAFLD) is a complex disorder that has evolved in recent years as the leading global cause of chronic liver damage.
Pirola, Carlos José, Sookoian, Silvia Cristina   +1 more
core   +1 more source

Immunolocalization of the Bcl-2 protein within hematopoietic neoplasms [PDF]

Blood, 1991
Abstract The Bcl-2 proto-oncogene was discovered at the t(14;18) breakpoint found in most follicular B-cell lymphomas and some diffuse large-cell lymphomas. Bcl-2 is unique among proto-oncogenes, being localized to mitochondria and extending cell survival by blocking programmed cell death.
M, Zutter, D, Hockenbery, G A, Silverman, S J, Korsmeyer   +3 more
openaire   +3 more sources