Results 11 to 20 of about 524,005 (214)
FOP is a centriolar satellite protein involved in ciliogenesis. [PDF]
PLoS ONE, 2013 Centriolar satellites are proteinaceous granules that are often clustered around the centrosome. Although centriolar satellites have been implicated in protein trafficking in relation to the centrosome and cilium, the details of their function and ...
Joanna Y Lee, Tim Stearns
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Proteolysis-targeting chimeras and their implications in breast cancer
Exploration of Targeted Anti-tumor Therapy, 2021 Breast cancer (BC) is a highly heterogeneous neoplasm of the mammary tissue, causing the deaths of a large number of women worldwide. Nearly 70% and 20% of BC cases are estrogen receptor alpha positive (ERα+) and human epidermal growth factor receptor 2 ...
Angeles C. Tecalco-Cruz +3 more
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Medicina, 2023 Background and Objectives: Papillary thyroid carcinoma (PTC) is one of the most common malignancies of the endocrine system. In order to improve the ability to predict tumor behavior, several studies have been conducted to search for surrogate prognostic
Mohammad Sheikh-Ahmad +10 more
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Molecular Cancer, 2023 Aim Chemoresistance is a major cause of treatment failure in colorectal cancer (CRC) therapy. In this study, the impact of the IGF2BP family of RNA-binding proteins on CRC chemoresistance was investigated using in silico, in vitro, and in vivo approaches.
Sandra Kendzia +28 more
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Frontiers in Oncology, 2020 Uveal melanoma, in spite of its rarity, represents the most common primitive intraocular malignant neoplasm of the adults; it affects choroid, ciliary bodied and iris and remains clinically silent for a long time, being accidentally discovered by routine
Giuseppe Broggi +11 more
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Biomolecules & Biomedicine, 2012 Interdigitating dendritic cell sarcoma is extremely rare neoplasm that mainly occurs in the lymph nodes. Only 45 cases have been reported in the literature to date.
Svjetlana Radović +6 more
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Faecal Proteomics and Functional Analysis of Equine Melanocytic Neoplasm in Grey Horses
Veterinary Sciences, 2022 Equine melanocytic neoplasm (EMN) is a common disease in older grey horses. The purpose of this study was to examine the potential proteins throughout EMN stages from faecal proteomic outlining using functional analysis.
Parichart Tesena +6 more
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Canine Transmissible Venereal Tumors: Aspects Related to Programmed Cell Death
Brazilian Journal of Veterinary Pathology, 2011 Canine transmissible venereal tumor (CTVT) is a neoplasm transmitted by the physical transfer of viable tumor cells by direct contact with injured skin and/or mucous tissue.
Daniela Stockmann +5 more
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Diagnostic Pathology, 2018 Background Plasma cell myeloma (PCM) is a neoplasm of terminally differentiated B lymphocytes with molecular heterogeneity. Although therapy-related myeloid neoplasms are common in plasma cell myeloma patients after chemotherapy, transdifferentiation of ...
Jonathon H. Gralewski +3 more
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Characteristics and clinical significance of polyploid giant cancer cells in laryngeal carcinoma
Laryngoscope Investigative Otolaryngology, 2021 Objectives We aimed to construct an induction system for polyploid giant cancer cells (PGCCs), as well as to investigate PGCC features and clinical significance.
Hui‐Ting Liu +9 more
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