Results 11 to 20 of about 525,558 (314)
Increased levels of a subset of angiogenesis-related plasma proteins in essential thrombocythemia
Background: Increased local angiogenesis is important for the growth and dissemination of cancer. The myeloproliferative neoplasm essential thrombocythemia (ET) is known to involve increased bone marrow angiogenesis.
Sofia Vikman +3 more
doaj +1 more source
Mixed neuroendocrine non-neuroendocrine neoplasm (MiNEN) is a rare type of gastric carcinoma with controversial diagnosis and treatment. Recent data implies that deficiency mismatch repair proteins inducing microsatellite instability are considered one ...
Thi Hong Chuyen Nguyen +7 more
doaj +1 more source
NDRG1 protein overexpression in malignant thyroid neoplasms [PDF]
The aim of this study was to examine the expression of the N-myc downstream-regulated gene 1 protein in benign and malignant lesions of the thyroid gland by immunohistochemistry.N-myc downstream-regulated gene 1 encodes a protein whose expression is induced by various stimuli, including cell differentiation, exposure to heavy metals, hypoxia, and DNA ...
Gerhard, Renê +4 more
openaire +5 more sources
FOP is a centriolar satellite protein involved in ciliogenesis. [PDF]
Centriolar satellites are proteinaceous granules that are often clustered around the centrosome. Although centriolar satellites have been implicated in protein trafficking in relation to the centrosome and cilium, the details of their function and ...
Joanna Y Lee, Tim Stearns
doaj +1 more source
Nonimmune fluorescent protein staining of neoplasms [PDF]
Abstract The nonimmunospecific tissue binding of protein-fluorochrome conjugates has been investigated. Such binding was specific in attachment to benign tissue, excluding malignant tissue, when fluorescein or rhodamine isocyanate was use according to the method of Hughes and Louis (1959) .
Miller, Edmund Kenneth +3 more
openaire +2 more sources
Proteolysis-targeting chimeras and their implications in breast cancer
Breast cancer (BC) is a highly heterogeneous neoplasm of the mammary tissue, causing the deaths of a large number of women worldwide. Nearly 70% and 20% of BC cases are estrogen receptor alpha positive (ERα+) and human epidermal growth factor receptor 2 ...
Angeles C. Tecalco-Cruz +3 more
doaj +1 more source
Common features between neoplastic and preneoplastic lesions of the biliary tract and the pancreas [PDF]
The bile duct system and pancreas show many similarities due to their anatomical proximity and common embryological origin. Consequently, preneoplastic and neoplastic lesions of the bile duct and pancreas share analogies in terms of molecular ...
Alvaro, D +10 more
core +1 more source
p53 protein overexpression in astrocytic neoplasms
Abnormalities of the p53 gene are the most common molecular change in human cancer. In the central nervous system, mutant p53 gene is frequently identified in the tumors with astrocytic differentiation. To investigate the relation between histologic subtypes and p53 protein overexpression, we examined 81 cases of astrocytic neoplasms (24 benign ...
M Y, Cho, S H, Jung, T S, Kim
openaire +2 more sources
Background and Objectives: Papillary thyroid carcinoma (PTC) is one of the most common malignancies of the endocrine system. In order to improve the ability to predict tumor behavior, several studies have been conducted to search for surrogate prognostic
Mohammad Sheikh-Ahmad +10 more
doaj +1 more source
Aim Chemoresistance is a major cause of treatment failure in colorectal cancer (CRC) therapy. In this study, the impact of the IGF2BP family of RNA-binding proteins on CRC chemoresistance was investigated using in silico, in vitro, and in vivo approaches.
Sandra Kendzia +28 more
doaj +1 more source

