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Retinoblastoma Protein Expression in Ovarian Epithelial Neoplasms
Gynecologic Oncology, 1998Progress has been made in identifying the molecular changes that occur in ovarian carcinoma; still our understanding of these changes and their interactions remains incomplete. In the present study the authors examined the expression of retinoblastoma protein, a tumor suppressor protein, in a spectrum of ovarian epithelial tumors including cystadenomas,
T H, Niemann +4 more
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Differential regulation of urine proteins in urothelial neoplasm
Journal of Proteomics, 2015Urothelial neoplasm of the urinary bladder has a high rate of multifocality and recurrence. To understand this we first need to understand the changes in the molecular level that distinguishes a normal individual from a patient and also a low grade neoplasm from a high grade.
Suchismita, Halder +4 more
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Massive protein plug in intraductal papillary mucinous neoplasm
Pancreatology, 2013A 56-year-old woman with diabetes mellitus visited our hospital for further examination. Abdominal ultrasonography showed an enlarged pancreas head, dilated pancreatic duct, and protrusion-like lesions in the main pancreatic duct, although tumors in the main pancreatic duct were unclear in computed tomography (Fig. 1).
Satoshi, Murao +2 more
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Expression of promyelocytic leukaemia protein in thyroid neoplasms
Histopathology, 2000AimsPromyelocytic leukaemia protein (PML) is an oncoprotein involved in the pathogenesis of acute promyelocytic leukaemia and is localized in distinct PML nuclear bodies. Our previous observation of overexpression of the PML in hormone‐sensitive normal tissues and malignant solid tumours, including the thyroid, led to this analysis of the PML ...
E, Yu, K W, Lee, H J, Lee
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Expression of S-100 protein in renal cell neoplasms
Human Pathology, 2006Polyclonal antibody to S-100 protein has been routinely applied for initial screening of various types of tumors, including, melanocytic tumors and neurogenic tumors. S-100 protein has been shown to have a broad distribution in human tissues, including renal tubules.
Fan, Lin +4 more
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Distinctive patterns of renal neoplasms containing Tamm-Horsfall protein
Virchows Archiv A Pathological Anatomy and Histopathology, 1993Sections of 114 renal neoplasms from adults, and 2 renal rhabdoid tumours from children, were examined by an indirect immunoperoxidase method using two antibodies to Tamm-Horsfall protein. Forty-five of the adult neoplasms were also examined with an antibody to proximal tubular brush border.
A J, Howie, N, Smithson, F, Raafat
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Antiinflammatory proteins associated with human and murine neoplasms
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 1986The immune mechanisms by which a host recognizes and destroys a growing tumor are undoubtedly complex and, as yet, incompletely understood. It is apparent, however, that mononuclear phagocytes play an important role in the defense against neoplastic disease and that the ability of monocytes and macrophages to accumulate at and within a growing tumor is
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Unusual expression of S‐100 protein in histiocytic neoplasms
Journal of Cutaneous Pathology, 1998Twenty‐nine cases of histiocytic neoplasms, some resembling juvenile xanthogranuloma (JXG) and others resembling reticulohistiocytoma (RH), were evaluated. Immunohistochemical stains were performed. In this series, seven cases were identified that expressed S‐100 protein positive cells.
M M, Tomaszewski, G P, Lupton
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Targeting a regulator of protein homeostasis in myeloproliferative neoplasms
Nature Medicine, 2016A new study demonstrates that dysregulation of proteostasis can be a transforming event in hematopoiesis that could prove to be therapeutically actionable for treatment of myeloproliferative neoplasms.
Lindsay M, LaFave, Ross L, Levine
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Immunoreactivity of neurofilament proteins in neuroendocrine neoplasms.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 1991We immunostained histologic sections of formalin-paraffin-processed specimens from 112 neuroendocrine tumors to evaluate the expression of intermediate filaments, especially neurofilament (NF) protein. The commercially available anti-human NF protein monoclonal antibody was raised against the Mr 200,000 and 70,000 components of neurofilaments.
I A, Shah, M O, Schlageter, D, Netto
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