Results 91 to 100 of about 748,361 (308)

Recurrence Plots in Nonlinear Time Series Analysis: Free Software [PDF]

Recurrence plots are graphical devices specially suited to detect hidden dynamical patterns and nonlinearities in data. However, there are few programs available to apply such a mehodology.
Dulce Contreras, Jorge Belaire-Franch
core  

The Impact of Clinical and Pathological Features on Intraductal Papillary Mucinous Neoplasm Recurrence After Surgical Resection: Long-Term Follow-Up Analysis. [PDF]

Ann Surg, 2022
Pflüger MJ, Griffin JF, Hackeng WM, Kawamoto S, Yu J, Chianchiano P, Shin E, Lionheart G, Tsai HL, Wang H, Rezaee N, Burkhart RA, Cameron JL, Thompson ED, Wolfgang CL, He J, Brosens LAA, Wood LD.   +17 more
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Risk factors for intrahepatic recurrence of hepatocellular carcinoma in cirrhotic patients treated by percutaneous ethanol injection

, 1997
Hepatocellular carcinoma (HCC) complicating cirrhosis has a high intrahepatic recurrence rate after treatment by surgical resection or percutaneous ethanol injection (PEI).
Astone, Antonio, Gasbarrini, Giovanni Battista, Rapaccini, Gian Ludovico, Pompili, Maurizio, Augusto Cedrone, Francescantonio de Luca, Maria Rosaria Villani, Gian Ludovico Rapaccini, Anna Grattagliano, Maurizio Pompili, Giovanni Gasbarrini, Eugenio Caturelli, Domenico Angelo Siena, Antonio Astone   +13 more
core   +1 more source

Scalp neoplasm associated with cranium bifidum in a 24-week human fetus [PDF]

, 1986
Prenatal ultrasonography at 24 weeks disclosed a fetus with a large mass protruding from the occiput. The mass was an invasive, undifferentiated mesenchymal neoplasm of the scalp associated with a defect in the occipital bone (cranium bifidum). The tumor
Kathleen P. Heidelberger, Heidelberger, Kathleen P., Mason Barr, Barr, Mason, Katerina Dorovini‐Zis, Dorovini-Zis, Katerina   +5 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Florid cutaneous papillomatosis as a marker of neoplastic recurrence [PDF]

, 2018
Florid cutaneous papillomatosis is a rare paraneoplastic dermatosis, most commonly associated with gastric adenocarcinoma. It is characterized by a sudden onset of hyperkeratotic papules, clinically indistinguishable from viral warts.
Esteves, M, Azevedo, F, Antunes, I, Esteves, M ; Antunes, I ; Azevedo, F, M Esteves, F Azevedo, I Antunes   +6 more
core   +1 more source

Recurrence-free survival stratified by size of HCC.

, 2022
The recurrence-free survival curve for two risk factors; the tumor diameter and the presence of active HCV infection. The recurrence-free survival was shorter in patients with larger tumors (p = 0.012).
Shun Kaneko (8735283), Chiaki Maeyashiki (749428), Kaoru Tsuchiya (793697), Kento Inada (8735286), Jun Itakura (554845), Masayuki Kurosaki (156560), Yuka Takahashi (172894), Kenta Takaura (1807024), Kouji Yamashita (12127220), Leona Osawa (8735289), Namiki Izumi (156627), Hiroyuki Nakanishi (698666), Shuhei Sekiguchi (8735292), Tomohiro Muto (12127223), Sakura Kirino (8735280), Yuka Hayakawa (675583), Yutaka Yasui (33074), Nobuharu Tamaki (793693), Mayu Higuchi (793694)   +18 more
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source