Results 101 to 110 of about 349,059 (308)
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Florid cutaneous papillomatosis as a marker of neoplastic recurrence [PDF]
, 2018 Florid cutaneous papillomatosis is a rare paraneoplastic dermatosis, most commonly associated with gastric adenocarcinoma. It is characterized by a sudden onset of hyperkeratotic papules, clinically indistinguishable from viral warts.
Esteves, M, Azevedo, F, Antunes, I
core +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Risk factors for intrahepatic recurrence of hepatocellular carcinoma in cirrhotic patients treated by percutaneous ethanol injection [PDF]
, 1997 Hepatocellular carcinoma (HCC) complicating cirrhosis has a high intrahepatic recurrence rate after treatment by surgical resection or percutaneous ethanol injection (PEI).
Astone, Antonio +3 more
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Low-Grade Appendiceal Mucinous Neoplasm Presenting as a Surgical Emergency: A Case Report [PDF]
, 2009 We present the case of a female patient admitted to our University Hospital with acute abdominal pain mimicking an intraperitoneal septic condition caused possibly by acute appendicitis.
Fotini Karasavvidou +7 more
core +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Low-grade mucinous neoplasm of the appendix managed with laparoscopic appendectomy [PDF]
, 2013 Mucocele of the appendix is uncommon and caused by a variety of pathologies. While the gold standard approach to these lesions has historically been exploratory laparotomy and right hemicolectomy, there is increasing experience with a minimally invasive ...
Jonas P DeMuro
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Frontiers in OncologyObjectiveTo evaluate the value of Gd-EOB-DTPA-enhanced MRI in the early diagnosis of occult intrahepatic recurrence after curative ablation for hepatocellular carcinoma (HCC).Materials and methodsThis retrospective study included 74 HCC patients who ...
Zhi Zhu +7 more
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Cystic nephroma: A multicystic renal neoplasm [PDF]
, 2014 A 42-year-old female presented with a complaint of abdominal pain for 3 months. Deep palpation revealed tenderness in the left lumbar region. Ultrasonography and contrast-enhanced computed tomography revealed a multiloculated cyst in the left kidney. The
Biswas, Prosenjit +13 more
core +1 more source