Results 81 to 90 of about 349,059 (308)

Spindle Cell Neoplasm of the Urinary Bladder in a Young Male: A Rare Case [PDF]

open access: yes, 2019
Case report: A 28‐year‐old male with no significant past medical history presented to the Emergency Department with clot retention and hypovolaemic shock. Emergency TURBT revealed a large solid bladder mass which was resected down to muscle.
Ali, Ahmad   +4 more
core   +1 more source

The effects of surgical margins on local control and survival in extremity soft tissue sarcomas

open access: yesActa Orthopaedica et Traumatologica Turcica, 2021
Objectives: We evaluated the effects of surgical margins and other prognostic factors on local control and survival in extremity soft tissue sarcomas. \nMethods: The study included 40 patients (34 males, 6 females; mean age 45 years; range 13 to 77 years)
Cemil Yildiz   +4 more
doaj  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Solid and Cystic Papillary Neoplasm of the Pancreas in a 18-Year-Old Female: A Case Report [PDF]

open access: yes, 2013
Context Solid and cystic papillary neoplasm of the pancreas is an extremely rare neoplasm that mostly affects young females in the mean age of 25 years and accounts for about 0.2-2.7% of all pancreatic tumors.
Abdelhady, Hosam, Fakhry, Hussein
core   +2 more sources

Squamous cell carcinoma of the palm: a case report

open access: yesActa Orthopaedica et Traumatologica Turcica, 2021
Squamous cell carcinoma (SCC) arising from the palm skin is very rare, having a very aggressive course and poor outcome. A 74-year-old male patient presented with a painful and rapidly growing nodular lesion, 20 mm in size, in the distal part of the ...
Hakan Agir   +2 more
doaj  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Extrahepatic intraductal papillary neoplasms of bile duct and Klatskin tumor: simultaneous occurrence and recurrence? [PDF]

open access: yes
This case report presents a 64-year-old woman with unique occurrence and recurrence of 2 different neoplastic entities, extrahepatic intraductal papillary neoplasm of bile duct and Klatskin tumor (hilar cholangiocarcinoma or central bile duct carcinoma),
Füzesi, Laszlo   +6 more
core   +1 more source

Anesthesia Options and the Recurrence of Cancer: What We Know so Far?

open access: yesLocal and Regional Anesthesia, 2020
Juan P Cata,1,2 Carlos Guerra,3 German Soto,4 Maria F Ramirez1,2 1Department of Anesthesiology and Perioperative Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; 2Anesthesiology and Surgical Oncology Research Group, Houston,
Cata JP, Guerra C, Soto G, Ramirez MF
doaj  

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

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