Molecular Oncology, EarlyView.Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen +12 more
wiley +1 more source
On Hyper-Generalized Recurrent Finsler Spaces [PDF]
arXiv, 2017 The aim of the present paper is to investigate new types of recurrence in Finsler geometry, namely, hyper-generalized recurrence and generalized conharmonic recurrence. The properties of such recurrences and their relations to other Finsler recurrences are studied.
arxiv
609 Endoscopic Management of Duodenal Neoplasms and Factors Leading to Incomplete Resection and Recurrence: Where Are We Now? [PDF]
, 2011 Reem Z. Sharaiha +6 more
openalex +1 more source
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
Molecular Oncology, EarlyView.The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova +18 more
wiley +1 more source
A Solution of Simultaneous Recurrences [PDF]
arXiv, 2013 The paper is devoted to the methods of solving simultaneous recurrences. Specifically, we discuss transformation of matrix recurrences to regular recurrences and propose a way of solving special matrix recurrences of order three by their decomposition to matrix recurrences of order two.
arxiv
Helicobacter pylori Eradication Reduces the Metachronous Recurrence of Gastric Neoplasms by Attenuating the Precancerous Process [PDF]
, 2015 Da Hyun Jung +12 more
openalex +1 more source
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Molecular Oncology, EarlyView.Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte +10 more
wiley +1 more source
Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
Cancer ReportsBackground Cancer trials increasingly use surrogate endpoints, but it is unclear how well recurrence‐free survival (RFS) or disease‐free survival (DFS) specifically predict overall survival (OS) in resectable esophageal cancer (EC).
Uchechukwu Love Anyaduba +5 more
doaj +1 more source
Patterns of recurrence and long-term outcomes in patients who underwent pancreatectomy for intraductal papillary mucinous neoplasms with high grade dysplasia: implications for surveillance and future management guidelines [PDF]
, 2017 Aaron U. Blackham +6 more
openalex +1 more source