Results 101 to 110 of about 130,630 (333)

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

Molecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou, Argyro Roumeliotou, Evangelia Pantazaka, Athanasios‐Nasir Shaukat, Athina Christopoulou, Angelos Koutras, Foteinos‐Ioannis Dimitrakopoulos, Vassilis Georgoulias, Anastasia Xagara, Evangelia Chantzara, Fillipos Koinis, Athanasios Kotsakis, Constantinos Stathopoulos, Galatea Kallergi   +13 more
wiley   +1 more source

Explainable machine learning for neoplasms diagnosis via electrocardiograms: an externally validated study [PDF]

arXiv
Background: Neoplasms remains a leading cause of mortality worldwide, with timely diagnosis being crucial for improving patient outcomes. Current diagnostic methods are often invasive, costly, and inaccessible to many populations. Electrocardiogram (ECG) data, widely available and non-invasive, has the potential to serve as a tool for neoplasms ...
arxiv  

The accumulation of myeloid‐derived suppressor cells participates in abdominal infection‐induced tumor progression through the PD‐L1/PD‐1 axis

Molecular Oncology, EarlyView.
This study explores how sepsis affects GC progression by creating an immunosuppressive environment. Our findings reveal that sepsis promotes immune dysregulation, enhancing tumor growth and metastasis. Targeting the PD‐1/PD‐L1 pathway with monoclonal antibodies shows potential for restoring immune function and improving outcomes in cancer patients ...
Yiding Wang, Ting Guo, Xiaofang Xing, Xijuan Liu, Xuejun Gan, Yingai Li, Yan Liu, Fei Shan, Zhouqiao Wu, Jiafu Ji, Ziyu Li   +10 more
wiley   +1 more source

Endoscopic ultrasound in the pre-therapeutic staging of gastroesophageal adenocarcinoma: the diagnostic value in defining patients eligible for a neoadjuvant chemotherapy regimen

Videosurgery and Other Miniinvasive Techniques, 2010
Introduction: Neoadjuvant chemotherapy regimens have been proven to decrease tumour size and stage and significantlyimprove progression-free and overall survival in the treatment of locoregional advanced gastroesophagealadenocarcinomas.
Wilko Staiger, Ulrich Ronellenfitsch, Ralf-Dieter Hofheinz, Philipp Ströbel, Miriam Hahn, Stefan Post, Peter Collet, Georg Kähler, Matthias Schwarzbach   +8 more
doaj  

Low accuracy of endoscopic ultrasonography for detailed T staging in gastric cancer

World Journal of Surgical Oncology, 2012
Background The accuracy of endoscopic ultrasonography (EUS) for preoperative staging of gastric cancer varies. The aim of this study was to investigate the accuracy of EUS tumor (T) and node (N) staging, and to identify the histopathological factors ...
Lee Han, Lim Chul, Park Jae, Cho Yu, Song Kyo, Jeon Hae, Park Cho   +6 more
doaj   +1 more source

Trend of incidence, subsite distribution and staging of colorectal neoplasms in the 15-year experience of a specialised cancer registry [PDF]

, 2004
Maurizio Ponz de Leòn, Massimiliano Marino, Piero Benatti, Giulio Rossi, Mirco Menigatti, Monica Pedroni, Carmela Di Gregorio, Lorena Losi, Francesca Borghi, A Scarselli, Giovanni Ponti, Barbara Roncari, Giovanni Zangardi, G. Abbati, E Ascari, Luca Roncucci   +15 more
openalex   +1 more source

The PTTG1/VASP axis promotes oral squamous cell carcinoma metastasis by modulating focal adhesion and actin filaments

Molecular Oncology, EarlyView.
VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park, Sang Shin Lee, Shihyun Kim, Yeonjun Lee, Gyeonwon Park, Jung Oh Kim, Jongho Choi   +6 more
wiley   +1 more source

Differential Expression of CD200 in B-Cell Neoplasms by Flow Cytometry Can Assist in Diagnosis, Subclassification, and Bone Marrow Staging [PDF]

, 2014
Pramoda Challagundla, L. Jeffrey Medeiros, Rashmi Kanagal‐Shamanna, Roberto N. Miranda, Jeffrey L. Jorgensen   +4 more
openalex   +1 more source

NanoCMSer: a consensus molecular subtype stratification tool for fresh‐frozen and paraffin‐embedded colorectal cancer samples

Molecular Oncology, EarlyView.
Consensus molecular subtypes (CMS1‐4) have been identified to study colorectal cancer heterogeneity and serve as potential biomarkers. In this study, we developed and evaluated NanoCMSer, a NanoString‐based classifier using 55 genes, optimized for FF and FFPE to facilitate the clinical evaluation of CMS subtyping.
Arezo Torang, Simone van de Weerd, Veerle Lammers, Sander van Hooff, Inge van den Berg, Saskia van den Bergh, Miriam Koopman, Jan N. IJzermans, Jeanine M. L. Roodhart, Jan Koster, Jan Paul Medema   +10 more
wiley   +1 more source

Klasifikacija i stadijumi melanoma kože [PDF]

Vojnosanitetski Pregled, 2003
Panajotović Ljubomir
doaj   +1 more source