Results 91 to 100 of about 163,967 (338)

Aplication of two-staged plasty for postoperative defect after Buschke – Löwenstein tumor removal

Инновационная медицина Кубани, 2019
The pointed condylomas caused by human papilloma virus (HPV) are more common seen among infections of anogenital area and they are sexually transmitted.
A. G. Baryshev, V. V. Polovinkin, A. S. Dikarev, S. B. Bogdanov, N. V. Khachaturyan, D. A. Valyakis, I. V. Pavlov, A. J. Mostovaya   +7 more
doaj   +2 more sources

Organoid Culture of Isolated Cells from Patient-derived Tissues with Colorectal Cancer

Chinese Medical Journal, 2016
Background: Colorectal cancer (CRC) is a heterogeneous disease; current research relies on cancer cell lines and animal cancer models, which may not precisely imitate inner human tumors and guide clinical medicine. The purpose of our study was to explore
Bing-Ying Xie, Ai-Wen Wu
doaj   +1 more source

Adenomatoid tumors of the male and female genital tract are defined by TRAF7 mutations that drive aberrant NF-kB pathway activation. [PDF]

, 2018
Adenomatoid tumors are the most common neoplasm of the epididymis, and histologically similar adenomatoid tumors also commonly arise in the uterus and fallopian tube.
Bastian, Boris C, Garg, Karuna, Goode, Benjamin, Grenert, James P, Joseph, Nancy M, Onodera, Courtney, Phillips, Joanna J, Rabban, Joseph T, Solomon, David A, Stevers, Meredith, Talevich, Eric, Van Ziffle, Jessica, Yeh, Iwei, Zaloudek, Charles   +13 more
core   +1 more source

Exploring cardiac impact of oral nicotine exposure in a transplantable Neoplasm Mice Model: Insights from biochemical analysis, morphometry, and molecular docking: Chlorella vulgaris green algae support

, 2023
Amany Abdel-Rahman Mohamed, Gihan G. Moustafa, Khlood M. El Bohy, Taghred M. Saber, Mohamed M.M. Metwally, Heba El Desoukey Mohammed, Ali H. El‐Far, Badriyah S. Alotaibi, Manal E. Alosaimi, Samah S. Abuzahrah, Leena S. Alqahtani   +10 more
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

FK 506 FOR LIVER, KIDNEY, AND PANCREAS TRANSPLANTATION [PDF]

, 1989
FK 506 was given for immunosuppression in 14 liver recipients. The drug was used in the first 10 cases because the recipients under conventional immunosuppression had rejection, nephrotoxicity, or both.
AnthonyJ. Demetris, Ashok Jain, Calne, John Fung, Kino, Murase, Ochiai, Ochiai, Raman Venkataramman, Satoru Todo, Starzl, Starzl, Starzl, Tamura, Thiru, ThomasE. Starzl, Todo, Todo, Todo, Todo   +19 more
core   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Pancreatic transplantation at the University of Pittsburgh. [PDF]

, 2004
Campath-1H preconditioning with tacrolimus monotherapy is an effective immunosuppressive regimen for pancreas transplantation, with acceptable patient and graft survival rates early after transplantation.
Abu-Elmagd, K, Basu, A, Bond, G, Khan, A, Marcos, A, Mazariegos, G, Reyes, J, Shapiro, R, Sindhi, R, Starzl, TE, Tan, HP, Thai, NL, Tom, K   +12 more
core  

Idiopathic noncirrhotic portal hypertension: current perspectives [PDF]

, 2016
The term idiopathic noncirrhotic portal hypertension (INCPH) has been recently proposed to replace terms, such as hepatoportal sclerosis, idiopathic portal hypertension, incomplete septal cirrhosis, and nodular regenerative hyperplasia, used to describe ...
D'AMATI, Giulia, Gioia, Stefania, Nicoletti, Valeria, PENTASSUGLIO, ILARIA, RIGGIO, Oliviero, VALENTE, MICHELE   +5 more
core   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source