Results 81 to 90 of about 597,042 (307)

Angiosarcoma at the site of nonfunctioning arteriovenous fistula in a kidney transplant recipient

Journal of Vascular Surgery Cases and Innovative Techniques, 2016
Angiosarcoma is a rare malignant neoplasm of the endothelial cells of blood vessels or lymphatics. We report a case of a 46-year-old male patient with a kidney transplant who developed epithelioid angiosarcoma at the site of a nonfunctioning ...
Riyadh A. Aldaabil, MD, Ahmed M. Alkhunaizi, MD, Najla A. Al-Dawsari, MD, Mohamad F. Dawamneh, MD, Rola Rabah, MD   +4 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Brain and bone metastasis of hepatocellular carcinoma after a liver transplantation – Case report

Brazilian Journal of Transplantation, 2015
Liver transplantation has improved the disease-free survival of patients with hepatocellular carcinoma, although local tumor recurrence, and less often extra hepatic metastasis are a possible outcome.
Ilka de Fátima Santana Ferreira Boin, Elaine Cristina Ataíde, Tiago Sevá-Pereira, Cecilia Amélia Fazzio Escanhoela   +3 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Early and late outcomes after heart transplantation in a low-volume transplant centre [PDF]

, 2012
Early (one year) and late (15 year) outcomes after heart transplantation in Malta were evaluated by means of a retrospective analysis of mortality and morbidity, derived from the transplant database.
Manche, Alexander
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

A transplant recipient with a mixed germ-cell ovarian tumor

Saudi Journal of Kidney Diseases and Transplantation, 2008
Immunosuppressed renal transplant recipients seem to be at significantly increased risk of developing neoplasms comparatively to nonimmunosuppressed individuals. A history of malignancy exposes the patient to a high risk for relapse after transplantation.
Ketata Hafed, Bouacida Mahdi, Bouhlel Abdelkader, Sahnoun Ahmed, Bahloul Ali, Yaich Soumaya, Hachicha Jamil, Mhiri Mohamed   +7 more
doaj  

Monomorphic post-transplant lymphoproliferative disorder of the tongue: case report and review of literature

Diagnostic Pathology, 2007
Background Post-transplant lymphoproliferative disorder (PTLD) is a spectrum of hematological diseases arising in context of immunosuppression after organ transplantation. PTLD can involve any organ; however, it is extremely rare in oral cavity.
Zimrin Ann, Gocke Christopher D, Burke Allen P, Tavora Fabio, Gonzalez-Cuyar Luis F, Sauk John J, Zhao Xiafeng F   +6 more
doaj   +1 more source

Transplant arteriosclerosis : an experimental study on risk factors and pathogenetic mechanisms [PDF]

, 2001
In this thesis, we focused on vascular damage inflicted after transplantation, i.e. injury of the graft vasculature as a result of an alloreactive response of the host against the graft, and everal factors in-fluencing this process.
Hillebrands, Jan Lucas, Hillebrands, Jan Lucas,, Hillebrands, Jan Lucas; id_orcid   +2 more
core   +17 more sources

Orthotopic liver transplantation in human-immunodeficiency-virus-positive patients in Germany [PDF]

, 2012
Objectives: This summary evaluates the outcomes of orthotopic liver transplantation (OLT) of HIV-positive patients in Germany. Methods: Retrospective chart analysis of HIV-positive patients, who had been liver-transplanted in Germany between July ...
T. Sauerbruch, J. Kittner, S. Manekeller, A. Paul, Anadol, Evrim, Beckebaum, Susanne, Rockstroh, Jürgen, T. Ganten, Paul, Andreas, Bickel, Markus, J. C. Kalff, Spengler, Ulrich, E. Anadol, M. Stoll, Zoufaly, Alexander, S. Beckebaum, Kittner, Jens Martin, M. Bickel, Hitzenbichler, Florian, Stoll, Matthias, Kalff, Jörg C., A. Zoufaly, Manekeller, Steffen, Ganten, Tom M., C. Berg, F. Hitzenbichler, J. K. Rockstroh, Radecke, Klaus, K. Radecke, Berg, C., U. Spengler, Sauerbruch, Tilman   +31 more
core   +1 more source