Results 111 to 120 of about 1,359,149 (381)
Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations
Advanced Functional Materials, EarlyView.Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan +4 more
wiley +1 more source
An Attempt to Induce a Specific Immunity to Transplantable Neoplasms [PDF]
The American Journal of Cancer, 1937 From the numerous experimental studies on acquired immunity to transplantable tumors one unquestionable fact emerges, namely that animals in which such neoplasms have regressed spontaneously are resistant to future inoculations with the same tumor strain (Clowes; Gaylord, Clowes and Baeslack; Sticker; Lewin; Rous and Murphy; Pearce and Brown).
openaire +1 more source
Advanced Functional Materials, EarlyView.Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana +2 more
wiley +1 more source
PLoS Medicine, 2009 Background Neural stem cells are currently being investigated as potential therapies for neurodegenerative diseases, stroke, and trauma. However, concerns have been raised over the safety of this experimental therapeutic approach, including, for example,
N. Amariglio +12 more
semanticscholar +1 more source
Advanced Functional Materials, EarlyView.A biomimetic nanomedicine (RBLN) constructed by loading natural antioxidants to clinically used layered double hydroxide nanoparticles is surface coated with fresh or senescent red blood cell membrane for balanced drug delivery to hepatocytes and KCs, thereby simultaneously alleviating liver oxidant stress and inflammation for effective drug‐induced ...
Jiahui Shao +8 more
wiley +1 more source
Adalimumab‐Poloxamer Conjugate for Bio‐Better: Enhanced Stability and Function
Advanced Functional Materials, EarlyView.Antibody‐polymer conjugates, particularly poloxamer conjugates, enhance antibody stability by improving tolerance to physicochemical stress and attenuating proteolysis by proteases. Furthermore, the higher affinity observed with poloxamer conjugation compared to standard PEGylation results in improved therapeutic efficacy in rheumatoid arthritis mouse ...
Jaewon Roh +3 more
wiley +1 more source
Seronegative Herpes simplex Associated Esophagogastric Ulcer after Liver Transplantation
Case Reports in Gastroenterology, 2008 Herpes simplex infection is characterized by acute or subacute infection, often followed by a chronic carrier state. Consecutive recurrences may flare up if immunocompromise occurs.
Edouard Matevossian +6 more
doaj +1 more source
THE BEHAVIOR IN TRANSPLANT OF LYMPHOCYTIC NEOPLASMS ARISING FROM PARENTAL THYMIC GRAFTS IN IRRADIATED, THYMECTOMIZED HYBRID MICE [PDF]
, 1956 L. W. Law, M Potter
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Advanced Functional Materials, EarlyView.A potent anionic citric acid‐based 3D‐printed scaffold is developed for the sustained and controlled release of orthobiologics to enhance orthopedic therapeutic efficacy. Comprehensive in vivo studies demonstrated effective bone fusion and high safety at a low dose of BMP‐2 delivered by the system, establishing it as a promising platform for safe ...
Se‐Hwan Lee +12 more
wiley +1 more source