Results 61 to 70 of about 1,359,149 (381)

Aberrant DNA Methylation Is Associated with a Poor Outcome in Juvenile Myelomonocytic Leukemia. [PDF]

open access: yesPLoS ONE, 2015
Juvenile myelomonocytic leukemia (JMML), an overlap of myelodysplastic / myeloproliferative neoplasm, is an intractable pediatric myeloid neoplasm. Epigenetic regulation of transcription, particularly by CpG methylation, plays an important role in tumor ...
Hirotoshi Sakaguchi   +18 more
doaj   +1 more source

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald   +18 more
wiley   +1 more source

The relationship of site to transplantability [PDF]

open access: yes, 1963
Thesis (M.A.)--Boston ...
Anderson, Leonard L.
core  

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

Multi-Visceral Transplantation in a 21-Year-Old Man with Prior Pancreatoblastoma

open access: yesInternational Journal of Organ Transplantation Medicine, 2016
Organ transplantation in patients with prior malignancy increases the risk of tumor recurrence post-transplantation due to immunosuppression. Only two cases of liver transplantation have so far been reported in children with hepatic metastases from ...
R Girlanda   +3 more
doaj  

Cadaveric renal transplantation under cyclosporine-steroid therapy [PDF]

open access: yes, 1983
Ninety-seven cadaveric renal transplants were performed upon 96 patients during 1981. The one year patient mortality was 2.1 per cent. Seventy of the recipients were undergoing trasplantation for the first time.
Hakala, TR   +4 more
core  

INFLUENCE OF LIGHT ON THE GROWTH AND MALIGNANCY OF A TRANSPLANTABLE NEOPLASM OF THE RABBIT [PDF]

open access: yesJournal of Experimental Medicine, 1927
An experiment is reported in which an environment of constant and continuous light excluding the shorter ultra-violet rays, and one of constant darkness, have influenced the course and character of a malignant disease of rabbits induced by a transplantable neoplasm.
Louise Pearce, C. M. Van Allen
openaire   +3 more sources

Cutaneous and mucosal neoplasms in bone marrow transplant recipients [PDF]

open access: yesCancer, 1990
Fifty-six long-term survivors of bone marrow allografts were followed for a minimum of 40 months after bone marrow transplantation (BMT) to determine the frequency of secondary malignancies. The 56 patients included ten with severe aplastic anemia (SAA), 16 with acute myeloblastic leukemia (AML), 11 with acute lymphoblastic leukemia (ALL), and 19 with ...
B. Patterson   +7 more
openaire   +3 more sources

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

open access: yesMolecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim   +11 more
wiley   +1 more source

Treatment of hepatic epithelioid hemangioendothelioma with liver transplantation [PDF]

open access: yes, 1988
Ten patients received liver transplants for unresectable epithelioid hemangioendothelioma (EHE). At the time of transplantation, four patients had microscopic metastases to the hilar lymph nodes, and one of the four also had metastases to a rib.
Esquivel, CO   +7 more
core   +1 more source

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