Results 61 to 70 of about 62,173 (364)

Aberrant DNA Methylation Is Associated with a Poor Outcome in Juvenile Myelomonocytic Leukemia. [PDF]

PLoS ONE, 2015
Juvenile myelomonocytic leukemia (JMML), an overlap of myelodysplastic / myeloproliferative neoplasm, is an intractable pediatric myeloid neoplasm. Epigenetic regulation of transcription, particularly by CpG methylation, plays an important role in tumor ...
Hirotoshi Sakaguchi, Hideki Muramatsu, Yusuke Okuno, Hideki Makishima, Yinyan Xu, Yoko Furukawa-Hibi, Xinan Wang, Atsushi Narita, Kenichi Yoshida, Yuichi Shiraishi, Sayoko Doisaki, Nao Yoshida, Asahito Hama, Yoshiyuki Takahashi, Kiyofumi Yamada, Satoru Miyano, Seishi Ogawa, Jaroslaw P Maciejewski, Seiji Kojima   +18 more
doaj   +1 more source

Mechanism of T-Cell Lymphomagenesis: Transformation of Growth-Factor-Dependent T-Lymphoblastoma Cells to Growth-Factor-Independent T-Lymphoma Cells [PDF]

, 1984
In a previous paper we described the induction by x-irradiation or radiation-induced leukemia virus-in-oculation of two classes of lymphoid T-cell neoplasms: The first class, designated T-cell lymphoblastoma (TCLB), consists of growth-factor-dependent ...
Altman, Amnon, Bogart, Mark H., Haas, Martin, Jones, O. W., Rothenberg, Ellen   +4 more
core   +1 more source

Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance

Molecular Oncology, EarlyView.
In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang, Haimei Wen, Ying Chen, Jingya Ning, Di Hu, Yujiao Dong, Chenyu Yao, Bo Yuan, Shuanying Yang   +8 more
wiley   +1 more source

Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value

Molecular Oncology, EarlyView.
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song, Zhe Wang, Guangji Zhang, Jiangxue Hou, Kaiqi Liu, Shuning Wei, Yan Li, Chunlin Zhou, Dong Lin, Min Wang, Hui Wei, Jianxiang Wang, Tao Cheng, Yingchang Mi   +13 more
wiley   +1 more source

Risk factors for relapse after allogeneic transplantation in acute myeloid leukemia

Haematologica, 2016
Acute myeloid leukemia is a clonal neoplasm derived from myeloid progenitor cells with a varying outcome. The initial goal of treatment is the achievement of complete remission, defined for over 40 years by morphology.
Gert J. Ossenkoppele, Jeroen J.W.M. Janssen, Arjan A. van de Loosdrecht   +2 more
doaj   +1 more source

A population-based study on myelodysplastic syndromes in the Lazio Region (Italy), medical miscoding and 11-year mortality follow-up. The Gruppo Romano-Laziale Mielodisplasie experience of retrospective multicentric registry [PDF]

, 2017
Data on Myelodysplastic Syndromes (MDS) are difficult to collect by cancer registries because of the lack of reporting and the use of different classifications of the disease.
Agabiti, Nera, Aloe Spiriti, Maria Antonietta, Andriani, Alessandro, Breccia, Massimo, Buccisano, Francesco, Cimino, Giuseppe, Criscuolo, Marianna, Davoli, Marina, De Fabritiis, Paolo, Faglioni, Laura, Fenu, Susanna, Fianchi, Luana, Gumenyuk, Svitlana, Latagliata, Roberto, Mancini, Stefano, Maurillo, Luca, Mayer, Flavia, Niscola, Pasquale, Nobile, Carolina, Piccioni, Anna Lina, Ricci, Roberto, Tafuri, Agostino, Tatarelli, Caterina, Trapã, Giulio, Voso, Maria Teresa, Zini, Gina   +25 more
core   +2 more sources

INFLUENCE OF LIGHT ON THE GROWTH AND MALIGNANCY OF A TRANSPLANTABLE NEOPLASM OF THE RABBIT [PDF]

Journal of Experimental Medicine, 1927
An experiment is reported in which an environment of constant and continuous light excluding the shorter ultra-violet rays, and one of constant darkness, have influenced the course and character of a malignant disease of rabbits induced by a transplantable neoplasm.
Louise Pearce, C. M. Van Allen
openaire   +3 more sources

Enhancing kidney transplantation through multi-agent kidney exchange programs: A comprehensive review and optimization models [PDF]

International Journal of Industrial Engineering Computations, 16(2). Growing Science (2024)
This paper presents a comprehensive review of the last two decades of research on Kidney Exchange Programs (KEPs), systematically categorizing and classifying key contributions to provide readers with a structured understanding of advancements in the field.
arxiv   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source

Multi-Visceral Transplantation in a 21-Year-Old Man with Prior Pancreatoblastoma

International Journal of Organ Transplantation Medicine, 2016
Organ transplantation in patients with prior malignancy increases the risk of tumor recurrence post-transplantation due to immunosuppression. Only two cases of liver transplantation have so far been reported in children with hepatic metastases from ...
R Girlanda, A Pozzi, CS Matsumoto, TM Fishbein   +3 more
doaj