Results 31 to 40 of about 1,488 (152)

Society for Endocrinology Clinical Practice Guideline for the Evaluation of Androgen Excess in Women

Clinical Endocrinology, Volume 103, Issue 4, Page 540-566, October 2025.
ABSTRACT Context Androgen excess is common in women and refers to clinical or biochemical evidence of elevated androgenic steroids such as testosterone. It is associated with underlying polycystic ovary syndrome in the majority of cases. However severe androgen excess is less common and may indicate the presence of underlying adrenal or ovarian ...
Yasir S. Elhassan, James M. Hawley, Leanne Cussen, Ali Abbara, Sophie A. Clarke, Punith Kempegowda, Rima K. Dhillon‐Smith, Puja Thadani, Maureen Busby, Lucy Owusu‐Darkwah, Rachel Marrington, W. Colin Duncan, Robert K. Semple, Richard Quinton, Michael W. O'Reilly   +14 more
wiley   +1 more source

Somatic co‐alteration signatures are prognostic in high‐grade TP53‐mutated myeloid neoplasms

British Journal of Haematology, Volume 206, Issue 4, Page 1103-1108, April 2025.
Summary To assess the relevance of co‐occurring somatic mutations in TP53‐mutated myeloid neoplasms with ≥10% blasts, we pooled 325 individuals from 10 centres. We focused on comparing three published somatic co‐alteration signatures comprising (1) nine MDS‐related genes (‘ICC‐MDSR’), (2) ICC‐MDSR + additional secondary mutations‐related genes (‘Tazi ...
Emily O. Symes, Peng Wang, Payal Sojitra, Madhu P. Menon, Anand A. Patel, Faheema Hasan, Sharmila Ghosh, Gregory W. Roloff, Qianghua Zhou, Anthony Findley, Talha Badar, Jingjing Zhang, Hamza Tariq, Hong Chang, Robert C. Bell, Anamarija M. Perry, Girish Venkataraman   +16 more
wiley   +1 more source

The genetic duet of concurrent RASAL1 and PTEN alterations promotes cancer aggressiveness by cooperatively activating the PI3K–AKT pathway

Molecular Oncology, Volume 19, Issue 1, Page 248-259, January 2025.
Comprehensive analyses of TCGA revealed common coexisting RASAL1 and PTEN alterations and their association with over‐activation of the PI3K–AKT pathway and poor clinical outcomes of cancer, which was recapitulated in mice with double Rasal1–Pten knockout and worsened by coexisting TP53 alterations.
Xiaopei Shen, Jie Tan, Rengyun Liu, Guangwu Zhu, Lisa Rooper, Mingzhao Xing   +5 more
wiley   +1 more source

Successful treatment of young childhood standard‐risk hepatoblastoma with cisplatin monotherapy using a central review system

Pediatric Blood &Cancer, Volume 71, Issue 11, November 2024.
Abstract Background The JPLT3‐S (Japanese Study Group for Pediatric Liver Tumors‐3) study, conducted cisplatin (CDDP) monotherapy for young children (<3 years old) with standard‐risk hepatoblastoma (HB) using a central review system in Japan. In the previous JPLT2 study, cases with resectable tumors without any annotation factors in the PRETEXT ...
Isamu Saeki, Kohmei Ida, Sho Kurihara, Kenichiro Watanabe, Makiko Mori, Tomoro Hishiki, Akiko Yokoi, Junya Fujimura, Shohei Honda, Yuki Nogami, Tomoko Iehara, Takuro Kazama, Masahiro Sekiguchi, Norihiko Kitagawa, Risa Matsumura, Motonari Nomura, Yohei Yamada, Ryo Hanaki, Hide Kaneda, Yuichi Takama, Takeshi Inoue, Yukichi Tanaka, Osamu Miyazaki, Hiroki Nagase, Tetsuya Takimoto, Kenichi Yoshimura, Eiso Hiyama   +26 more
wiley   +1 more source

A review of the current treatment methods for retroperitoneal fibrosis with obstructive uropathy

BJUI Compass, Volume 5, Issue 8, Page 835-845, August 2024.
Abstract Introduction and aims Retroperitoneal fibrosis (RPF) is a fibroinflammatory disease in which patients may suffer obstructive uropathy (OU). The optimum treatment strategy for RPF with secondary OU is currently unclear, and the aim of this literature review is to assess the methods used to treat this patient cohort.
Charles Carey, Gerard Gurumurthy, Richard Napier‐Hemy, Bachar Zelhof   +3 more
wiley   +1 more source

Tratamiento quirúrgico del cáncer de esófago

Cirugía del Uruguay, 2020
Se presentan diez casos de resección de cáncer del esófago. Siete de tercio medio y tres de tercio inferior. Los cánceres-del tercio medio fueron abordados por toracotomía derecha.
Manuel Albo Volonté, Roberto Rubio
doaj  

S1‐Guideline Sebaceous Carcinoma

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 22, Issue 5, Page 730-747, May 2024.
Summary Sebaceous gland carcinomas are rare malignant cutaneous adnexal tumors with sebocytic differentiation. The typical predilection area is the head and neck region, where sebaceous gland carcinomas are the most common malignant adnexal tumors of the skin.
Jochen Utikal, Pia Nagel, Verena Müller, Jürgen C. Becker, Edgar Dippel, Alexander Frisman, Martin Gschnell, Klaus Griewank, Eva Hadaschik, Doris Helbig, Uwe Hillen, Ulrike Leiter, Claudia Pföhler, Lisa Krönig, Mirjana Ziemer, Selma Ugurel   +15 more
wiley   +1 more source

¿Tumoración mediastinal o aneurisma aórtico? Presentación de un caso diagnosticado por videotoracoscopía y operado con cirugía de mínimo acceso

Revista Cubana de Cardiología y Cirugía Cardiovascular, 2011
Se presenta la historia clínica de un paciente afectado por tos pertinaz de seis meses de evolución, el cual produjo polémica diagnóstica entre la aortografía y la tomografía axial computadorizada simple y endovenosa (¿aneurisma aortico o tumor ...
Julio Cesar Echarte Martínez, Fausto Rodríguez Salgueiro, José Dario Barrera Sarduy, José Luis Fonseca Cruz   +3 more
doaj  

CD81 promotes proliferation and predicts survival in lung squamous cell carcinoma

Clinical and Translational Medicine, Volume 16, Issue 4, April 2026.
Ryu Kanzaki, Steven Reid, Paulina Bolivar, Sara Larsson, Yasushi Shintani, Kristian Pietras   +5 more
wiley   +1 more source

The Predictive Role of Lactate in the Emergency Department in Patients with Severe Dyspnea

Emergency Medicine International, Volume 2024, Issue 1, 2024.
Objective. An accurate identification of patients at the need for prioritized diagnostics and care are crucial in the emergency department (ED). Blood gas (BG) analysis is a widely available laboratory test, which allows to measure vital parameters, including markers of ventilation and perfusion.
Maciej Niczewski, Szymon Gawęda, Paulina Kluszczyk, Mikołaj Rycerski, Daria Syguła, Anna Danel, Szymon Szmigiel, Konrad Mendrala, Aleksandra Oraczewska, Czarosław Kijonka, Monika Nowicka, Michał Wita, Tomasz Cyzowski, Grzegorz Brożek, Maciej Dyrbuś, Szymon Skoczyński, Roberto Cirocchi   +16 more
wiley   +1 more source