Results 141 to 150 of about 7,836,429 (310)

Biophysical aspects of radiation carcinogenesis [PDF]

, 1982
Becker, Frederick Fenimore, Kellerer, Albrecht M., Rossi, Harald H.   +2 more
core   +1 more source

Experimentally-Induced Neoplasms in the Skin of Mice

Journal of Investigative Dermatology, 1965
Among animals which have been topically treated with chemical carcinogens, differences in susceptibility to tumor induction as a function of age have been reported for both haired (1, 2) and hairless (3) mice. This investigation was undertaken to test a third member of this allelic series, i.e.
openaire   +4 more sources

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Melatonin: does it have utility in the treatment of haematological neoplasms?

British Journal of Pharmacology, 2018
Tian Li, Zhi Yang, Shuai Jiang, Wen-cheng Di, Zhiqiang Ma, Wei Hu, Fulin Chen, R. Reiter, Yang Yang   +8 more
semanticscholar   +1 more source

Summary of the discussion on mammary carcinogenesis in the rat [PDF]

, 1982
Broerse, J. J., Gerber, G. B., Kellerer, Albrecht M.   +2 more
core   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Predicting the Grade of Dysplasia of Pancreatic Cystic Neoplasms Using Cyst Fluid DNA Methylation Markers

Clinical Cancer Research, 2017
Tatsuo Hata, Marco dal Molin, Seung‐Mo Hong, K. Tamura, Masaya Suenaga, Jun Yu, Hiraku Sedogawa, M. Weiss, elliot k fishman, A. Lennon, R. Hruban, M. Goggins   +11 more
semanticscholar   +1 more source

Induction of mammary neoplasms in the ACI rat by 430-keV neutrons, X-rays, and diethylstilbestrol [PDF]

, 1982
Chmelevsky, D., Holtzman, S., Kellerer, Albrecht M., Shellabarger, C. J., Stone, J. P.   +4 more
core   +1 more source

The Effect of Drug Vintage on Survival: Micro Evidence from Puerto Rico's Medicaid Program [PDF]

Using micro data on virtually all of the drugs and diseases of over 500,000 people enrolled in Puerto Rico's Medicaid program, we examine the impact of the vintage (original FDA approval year) of drugs used to treat a patient on the patient's 3-year ...
Frank R. Lichtenberg
core