Results 151 to 160 of about 571,072 (310)

Image Segmentation of Skin Neoplasms Using the Active Contour Method

Computer vision technologies are being actively introduced into modern life, including medical practice. The development of such technologies has led to the emergence of computer systems that allow the detection and classification of skin diseases with a
Solomatin M.A., Sergeev V.Yu., Voronin A.E., Arkhangelskaya I.V., Petukhova A.I., Nikitaev V.G., Pronichev A.N., Tamrazova O.B., Zanegina T.P., Sergeev Yu.Yu., Bagnova P.Yu., Soshnina A.V.   +11 more
core   +1 more source

MV-HAGCN: Prediction of miRNA-Disease Association Based on Multi-View Hybrid Attention Graph Convolutional Network. [PDF]

Int J Mol Sci
Xing K, Zhang Y, Zhu W.
europepmc   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Mapping metabolic reprogramming in lung and breast cancer through integrative bioinformatics. [PDF]

PLoS One
Al-Damook N, Sakkal M, Khair M, Mousa WK, Ghemrawi R.   +4 more
europepmc   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Multi-source Feature Classification Model of Pancreatic Mucinous and Serous Cystic Neoplasms Based on Deep Learning

This study aims to classify and differentiate mucinous and serous cystic neoplasms of the pancreas using a multi-source feature classification model based on deep learning for preoperative auxiliary diagnosis.
HUANG Ziheng, XU Zhenshun, SHAO Chengwei, WU Jie, YUAN Xiaohan, BIAN Yun   +5 more
core   +1 more source

Myeloid Mir34a suppresses initiation and progression of intestinal and colitis-induced colon cancers in APC^min mice. [PDF]

Cell Death Dis
Chen Y, Liu F, König J, Bouznad N, Hermeking H.   +4 more
europepmc   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Editorial: Evaluating differentiation therapy and biomarkers in myeloid malignancies. [PDF]

Front Oncol
Noguera NI, Hasan SK, Cicconi L.
europepmc   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source