Cells, 2021 In our previous study, while chronic lymphocytic leukemia (CLL) cases showed higher levels of B and T lymphocyte attenuator (BTLA) mRNA compared to controls, lower BTLA protein expression was observed in cases compared to controls.
Lidia Karabon +9 more
doaj +1 more source
Experimental Modeling of Myeloproliferative Neoplasms
Genes, 2019 Myeloproliferative neoplasms (MPN) are genetically very complex and heterogeneous diseases in which the acquisition of a somatic driver mutation triggers three main myeloid cytokine receptors, and phenotypically expresses as polycythemia vera (PV), essential thrombocytosis (ET), and primary myelofibrosis (PMF).
Olga Babosova +3 more
openaire +2 more sources
Neural Transformers for Intraductal Papillary Mucosal Neoplasms (IPMN) Classification in MRI images [PDF]
, 2022 Early detection of precancerous cysts or neoplasms, i.e., Intraductal Papillary Mucosal Neoplasms (IPMN), in pancreas is a challenging and complex task, and it may lead to a more favourable outcome. Once detected, grading IPMNs accurately is also necessary, since low-risk IPMNs can be under surveillance program, while high-risk IPMNs have to be ...
arxiv +1 more source
Exploring the interdependencies of research funders in the UK [PDF]
, 2014 Investment in medical research is vital to the continuing improvement of the UK's health and wealth. It is through research that we expand our understanding of disease and develop new treatments for patients.
Crane, P +13 more
core +1 more source
Raman spectroscopy in noninvasive optical diagnostics of skin neoplasms [PDF]
Наука и инновации в медицине, 2023 Aim to propose a schematic design of a new prototype having a potential for mass production and use in medical institutions for routine diagnostics of skin neoplasms. Material and methods.
Oleg I. Kaganov +3 more
doaj +1 more source
Mathematical modelling, selection and hierarchical inference to determine the minimal dose in IFN$α$ therapy against Myeloproliferative Neoplasms [PDF]
Mathematical Medicine and Biology: A Journal of the IMA, Volume
41, Issue 2, June 2024, Pages 110-134, 2021 Myeloproliferative Neoplasms (MPN) are blood cancers that appear after acquiring a driver mutation in a hematopoietic stem cell. These hematological malignancies result in the overproduction of mature blood cells and, if not treated, induce a risk of cardiovascular events and thrombosis. Pegylated IFN$\alpha$ is commonly used to treat MPN, but no clear
arxiv +1 more source
Journal of Immunology Research, 2020 Chronic lymphocytic leukemia (CLL) is characterized by the peripheral accumulation of neoplastic B cells and is frequently complicated by the systemic immunosuppression associated with an impairment in B and T lymphocyte activation.
L. Karabon +10 more
doaj +1 more source
Chromogranin A: From Laboratory to Clinical Aspects of Patients with Neuroendocrine Tumors [PDF]
, 2018 Background. Neuroendocrine tumors (NETs) are characterized by having behavior and prognosis that depend upon tumor histology, primary site, staging, and proliferative index.
Baldelli, Roberto +8 more
core +1 more source
Low-Grade Appendiceal Mucinous Neoplasm Involving the Endometrium and Presenting with Mucinous Vaginal Discharge. [PDF]
, 2016 Primary appendiceal mucinous lesions are uncommon and represent a spectrum from nonneoplastic mucous retention cysts to invasive adenocarcinoma. Low-grade appendiceal mucinous neoplasms (LAMNs) represent an intermediate category on this spectrum and can ...
Baumgartner, Joel M +4 more
core +4 more sources
MDHGI: Matrix Decomposition and Heterogeneous Graph Inference for miRNA-disease association prediction. [PDF]
PLoS Computational Biology, 2018 Recently, a growing number of biological research and scientific experiments have demonstrated that microRNA (miRNA) affects the development of human complex diseases.
Xing Chen, Jun Yin, Jia Qu, Li Huang
doaj +1 more source