Results 11 to 20 of about 8,267,225 (310)

JAK2V617F variant allele frequency >50% identifies patients with polycythemia vera at high risk for venous thrombosis

Blood Cancer Journal, 2021
Arterial (AT) and venous (VT) thrombotic events are the most common complications in patients with polycythemia vera (PV) and are the leading causes of morbidity and mortality.
Paola Guglielmelli, Giuseppe G. Loscocco, Carmela Mannarelli, Elena Rossi, Francesco Mannelli, Francesco Ramundo, Giacomo Coltro, Silvia Betti, Chiara Maccari, Sara Ceglie, Patrizia Chiusolo, Chiara Paoli, Tiziano Barbui, Ayalew Tefferi, Valerio De Stefano, Alessandro M. Vannucchi   +15 more
doaj   +1 more source

Comprehensive Genomic Profiling of Gastroenteropancreatic Neuroendocrine Neoplasms (GEP-NENs)

Clinical Cancer Research, 2020
Purpose: GEP-NENs are rare malignancies with increasing incidence. Their molecular characteristics are still undefined. We explored the underlying biology of GEP-NENs and the differences between gastrointestinal (GI) and pancreatic (PNEN), high-grade (HG)
A. Puccini, K. Poorman, M. Salem, Davide Soldato, A. Seeber, R. Goldberg, A. Shields, J. Xiu, F. Battaglin, M. D. Berger, R. Tokunaga, M. Naseem, A. Barzi, S. Iqbal, Wu Zhang, S. Soni, Jimmy J. Hwang, P. Philip, S. Sciallero, W. Korn, J. Marshall, H. Lenz   +21 more
semanticscholar   +1 more source

Assessment of deep neural networks for the diagnosis of benign and malignant skin neoplasms in comparison with dermatologists: A retrospective validation study

PLoS Medicine, 2020
Background The diagnostic performance of convolutional neural networks (CNNs) for diagnosing several types of skin neoplasms has been demonstrated as comparable with that of dermatologists using clinical photography.
S. Han, I. Moon, Seong Hwan Kim, J. Na, M. Kim, Gyeong-Hun Park, I. Park, Keewon Kim, Woohyung Lim, J. H. Lee, S. Chang   +10 more
semanticscholar   +1 more source

Effect of colostomy on experimentally produced neoplasms of the colon of the rat [PDF]

Cancer, 1967
As a means of determining the effect of the fecal stream in the pathogenesis of experimentally produced colonic tumors in Wistar strain rats, simple colostomies were performed in the left colon of 57 female rats at approximately 4 cm above the anus. Fifty-four rats received daily subcutaneous injections, 5 days per week, of the carcinogen 3:2'dimethyl ...
Harlan J. Spjut, Antonio Navarrete
openaire   +3 more sources

Significance of HLA-E and its two NKG2 receptors in development of complications after allogeneic transplantation of hematopoietic stem cells

Frontiers in Immunology, 2023
Transplantation of hematopoietic stem cells (HSCT) is a procedure commonly used in treatment of various haematological disorders which is associated with significantly improved survival rates.
Jagoda Siemaszko, Piotr Łacina, Donata Szymczak, Agnieszka Szeremet, Maciej Majcherek, Anna Czyż, Małgorzata Sobczyk-Kruszelnicka, Wojciech Fidyk, Iwona Solarska, Barbara Nasiłowska-Adamska, Patrycja Skowrońska, Maria Bieniaszewska, Agnieszka Tomaszewska, Grzegorz W. Basak, Sebastian Giebel, Tomasz Wróbel, Katarzyna Bogunia-Kubik   +16 more
doaj   +1 more source

Neutrophil-to-lymphocyte ratio is a novel predictor of venous thrombosis in polycythemia vera

Blood Cancer Journal, 2022
We investigated the neutrophil-to-lymphocyte ratio (NLR) as a predictor of thrombosis in polycythemia vera (PV). After a median follow-up of 2.51 years, of 1508 PV patients enrolled in the ECLAP study, 82 and 84 developed arterial and venous thrombosis ...
Alessandra Carobbio, Alessandro Maria Vannucchi, Valerio De Stefano, Arianna Masciulli, Paola Guglielmelli, Giuseppe Gaetano Loscocco, Francesco Ramundo, Elena Rossi, Yogendra Kanthi, Ayalew Tefferi, Tiziano Barbui   +10 more
doaj   +1 more source

BTLA Expression in CLL: Epigenetic Regulation and Impact on CLL B Cell Proliferation and Ability to IL-4 Production

Cells, 2021
In our previous study, while chronic lymphocytic leukemia (CLL) cases showed higher levels of B and T lymphocyte attenuator (BTLA) mRNA compared to controls, lower BTLA protein expression was observed in cases compared to controls.
Lidia Karabon, Anna Andrzejczak, Lidia Ciszak, Anna Tomkiewicz, Aleksandra Szteblich, Agnieszka Bojarska-Junak, Jacek Roliński, Dariusz Wołowiec, Tomasz Wróbel, Agata Kosmaczewska   +9 more
doaj   +1 more source

Raman spectroscopy in noninvasive optical diagnostics of skin neoplasms [PDF]

Наука и инновации в медицине, 2023
Aim to propose a schematic design of a new prototype having a potential for mass production and use in medical institutions for routine diagnostics of skin neoplasms. Material and methods.
Oleg I. Kaganov, Yuliya G. Loginova, Aleksandr A. Moryatov, Sergei V. Kozlov   +3 more
doaj   +1 more source

Solid-pseudopapillary tumor of the pancreas: A single center experience [PDF]

, 2016
open6noAim of this study was to review the institutional experience of solid-pseudopapillary tumors of the pancreas with particular attention to the problems of preoperative diagnosis and treatment.
Alberto Fantin, Cosimo Sperti, Enrico Dalla Bona, Gioia Pozza, Michele Valmasoni, Valentina Beltrame   +5 more
core   +3 more sources

Analysis of the action of Himatanthus drasticus in progression of urethane-induced lung cancer in mice [PDF]

Einstein (São Paulo), 2011
Objective: To evaluate the effect of janaguba in inhibiting the development of lung cancer in an experimental urethane-induced model. Methods: a total of 3mg/kg urethane was injected in 51 Balb-C mice aged 7-13 weeks of life.
Wendy Caroline de Souza Costa França, Ana Cláudia Rodrigues Lopes Amaral de Souza, José Antônio Cordeiro, Patricia Maluf Cury   +3 more
doaj   +3 more sources