Results 41 to 50 of about 571,072 (310)

Incidence and multiplicity of hepatic neoplasms and FCA in the experimental mice.

, 2015
aSignificantly different from group 3 by Fisher's exact probability test (P < 0.05)Incidence and multiplicity of hepatic neoplasms and FCA in the experimental mice.
Hisashi Tsurumi (455722), Masaya Kubota (724802), Masahito Shimizu (455716), Takahiro Kochi (455718), Atsushi Baba (724801), Yohei Shirakami (455717), Tomohiko Ohno (724800), Takuji Tanaka (9733), Hisataka Moriwaki (455724)   +8 more
core   +1 more source

Optimizing IFN Alpha Therapy against Myeloproliferative Neoplasms

, 2023
International audienceMyeloproliferative Neoplasms (MPNs) are hematological malignancies that result from acquired driver mutations in hematopoietic stem cells (HSCs), causing overproduction of blood cells and an increased risk of thrombo-hemorrhagic ...
Isabelle Plo, Gurvan Hermange, Plo, Isabelle, Hermange, Gurvan, Paul-Henry Cournède, Cournède, Paul-Henry   +5 more
core   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

Primary Neoplasms of Bones in Mice

, 2011
To compare and summarize the mechanisms, frequencies of occurrence, and classification schemes of spontaneous, experimental, and genetically engineered mouse skeletal neoplasms, the literature was reviewed, and archived case material at The Jackson ...
O. Foreman, J. P. Sundberg, A. M. Kavirayani   +2 more
core   +1 more source

CircRNAs Are Here to Stay: A Perspective on the MLL Recombinome

Frontiers in Genetics, 2019
Chromosomal translocations harbored by cancer genomes are important oncogenic drivers. In MLL rearranged acute leukemia (MLLre) MLL/KMT2A fuses with over 90 partner genes.
Anna Dal Molin, Silvia Bresolin, Enrico Gaffo, Caterina Tretti, Elena Boldrin, Lueder H. Meyer, Paola Guglielmelli, Alessandro M. Vannucchi, Geertruij te Kronnie, Stefania Bortoluzzi   +9 more
doaj   +1 more source

Increased Risk of Sarcomas in Children With Congenital Anomalies: Findings From the Genetic Overlap Between Anomalies and Cancer in Kids (GOBACK) Registry Linkage Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters, Ji Yun Tark, Tiffany M. Chambers, Tania A. Desrosiers, Michael E. Scheurer, Charles Shumate, Wendy N. Nembhard, Mahsa M. Yazdy, Eirini Nestoridi, Amanda E. Janitz, Jean Paul Tanner, Russell S. Kirby, Jason L. Salemi, Yao Yu, Chad D. Huff, Sharon E. Plon, Philip J. Lupo, Jeremy M. Schraw   +17 more
wiley   +1 more source

Pathology, genetics and precursors of human and experimental pancreatic neoplasms: An update.

, 2015
Over the past decade, there have been substantial improvements in our knowledge of pancreatic neoplasms and their precursor lesions. Extensive genetic analyses, recently using high-throughput molecular techniques and next-generation sequencing ...
Esposito, Irene;Segler, Angela;Steiger, Katja;Klöppel, Günter
core   +1 more source

Prognostic stratification in venetoclax-based acute myeloid leukemia treatments: the molecular prognostic risk signature tested in a real-world setting

Haematologica
Not available.
Gaia Ciolli, Matteo Piccini, Francesco Mannelli, Giacomo Gianfaldoni, Barbara Scappini, Laura Fasano, Francesca Crupi, Elisa Quinti, Andrea Pasquini, Jessica Caroprese, Giada Rotunno, Fabiana Pancani, Leonardo Signori, Chiara Maccari, Fiorenza I. Vanderwert, Paola Guglielmelli, Alessandro M. Vannucchi   +16 more
doaj   +1 more source

Efficient framework for predicting MiRNA-disease associations based on improved hybrid collaborative filtering

BMC Medical Informatics and Decision Making, 2021
Background Accumulating studies indicates that microRNAs (miRNAs) play vital roles in the process of development and progression of many human complex diseases.
Ru Nie, Zhengwei Li, Zhu-hong You, Wenzheng Bao, Jiashu Li   +4 more
doaj   +1 more source

Prognosis of Long‐Term Continuous Renal Replacement Therapy and the Impact of Combined Continuous Intravenous Sodium Infusion Therapy

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients requiring long‐term continuous renal replacement therapy (CRRT) generally have poor prognoses. This study evaluated whether adding continuous intravenous sodium infusion (cIVNa) is associated with improved hemodynamics and outcomes in patients undergoing long‐term CRRT for ≥ 7 days.
Akinori Yamaguchi, Atsuyoshi Mita, Kosuke Sonoda, Makoto Harada, Koji Hashimoto, Hiroshi Imamura, Yuji Kamijo   +6 more
wiley   +1 more source