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Transmissible Agent Associated with 26 Types of Experimental Mouse Neoplasms [PDF]
Science, 1960 A transmissible agent or factor has been found to be associated with all transplanted and spontaneous experimental tumors examined. This observation was made possible by utilization of a biochemical response of normal animals when inoculated with plasma or organ extracts from tumor-bearing hosts.
Riley, V +3 more
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Experimental spinal cord compression by epidural neoplasms
Neurology, 1977We have developed an experimental model of spinal cord compression in rats. Tumor injected anterior to the T-12 vertebral body grows through the intervertebral foramina to compress the cord and produces paraplegia in 3 to 4 weeks. Evidence for vasogenic edema in spinal cord compressed by tumor includes increased water content, leakage of horseradish ...
William R. Shapiro +3 more
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Tocopherol in Irradiation of Experimental Neoplasms Influence of dose and administration
Acta Radiologica: Oncology, 1981The influence of tocopherol, administered intramuscularly in different single doses, on the effect of local irradiation of a transplanted rat sarcoma was investigated. Tocopherol in doses of 5, 25 or 50 mg/100 g body weight enhanced significantly the tumour growth retardation induced by irradiation. Tocopherol in a dose of 100 mg/100 g body weight as a
H.-I. Peterson, A. Kägerud
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Peripheral neuropathy associated with experimental plasma cell neoplasm in the mouse
Journal of the Neurological Sciences, 1987In order to investigate the role of paraproteins in the production of neuropathy we experimentally induced monoclonal immunoglobulin-producing tumours into 32 BALB/c mice by injecting mineral oil or pristane intraperitoneally. In 11 mice morphologic and histometric studies of the sciatic nerve revealed the presence of neuropathy.
R. Nemni +5 more
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Cryosurgical Treatment of Palpebral Neoplasms: Clinical and Experimental Results
Veterinary Surgery, 1979Cryosurgical treatment of canine eyelid neoplasms has resulted in destruction of the tumors while maintaining acceptable cosmetic results. Both clinical experience and experimental studies have shown the normal canine palpebra to be quite resistant to excessive permanent deformity secondary to freezing.
David L. Holmberg, Stephen J. Withrow
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Pathology, genetics and precursors of human and experimental pancreatic neoplasms: An update
Pancreatology, 2015Over the past decade, there have been substantial improvements in our knowledge of pancreatic neoplasms and their precursor lesions. Extensive genetic analyses, recently using high-throughput molecular techniques and next-generation sequencing methodologies, and the development of sophisticated genetically engineered mouse models closely recapitulating
Katja Steiger +3 more
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An experimental model for selective production of neoplasms of the peripheral nervous system
Acta Neuropathologica, 1973Ninety-three tumors of the peripheral nervous system (PNS) were produced in 30 male Fischer (CDF) rats following intravenous injection of 10 mg/kg of N-methyl N-nitrosourea (MNU) twice weekly for 9 weeks. The high susceptibility of CDF rats to an optimal dose of MNU provides a useful experimental model to study induction and pathogenesis of tumors of ...
James A. Swenberg +2 more
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The oncostatic effect of methyl-CCNU on various experimental lymphoreticular neoplasms
Leukemia Research, 1982Studies on the chemotherapeutic potential of methyl-CCNU on experimental leukemias were undertaken. A number of murine transplantable in vivo lines (chemical carcinogen-induced T and B leukemias; radiation- and viral-induced T leukemias of C57BL/6, C3H/eb and SJL/J origin; radiation-induced myeloid leukemias and spontaneous reticulum cell neoplasms of ...
Nechama Haran-Ghera +3 more
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Treatment of experimental spinal cord compression caused by extradural neoplasms
Journal of Neurosurgery, 1977✓ Epidural spinal cord compression was produced in rats by injection of Walker 256 carcinoma cell suspension anterior to the T-12 or T-13 vertebral body. The tumor grows through the intervertebral foramina to compress the spinal cord and produce paraplegia in 3 to 4 weeks. The effect of several treatments upon clinical signs was assessed. Dexamethasone
William R. Shapiro +4 more
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Effects of intestinal bacteria on the development of colonic neoplasm: an experimental study
European Journal of Cancer Prevention, 1999Effects of intestinal microflora on the development of colonic neoplasm induced by 1,2-dimethylhydrazine (DMH) were observed using conventionalized and gnotobiotic mouse models. The incidence of colonic adenoma in germ-free mice (IQI/jic) (GF), mice conventionalized after DMH injection (Cvz-post-DMH) and conventionalized mice (Cvz, conventionalized ...
H Horie +5 more
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